Uniting Native Capillary Electrophoresis and Multistage Ultraviolet Photodissociation Mass Spectrometry for Online Separation and Characterization of Escherichia coli Ribosomal Proteins and Protein Complexes.

Autor: Mehaffey MR; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States., Xia Q; CMP Scientific Corporation, Brooklyn, New York, New York 11226, United States., Brodbelt JS; Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2020 Nov 17; Vol. 92 (22), pp. 15202-15211. Date of Electronic Publication: 2020 Nov 06.

Elusive structural changes of New Delhi metallo-β-lactamase revealed by ultraviolet photodissociation mass spectrometry.

Autor: Mehaffey MR; Department of Chemistry, University of Texas at Austin Austin TX 78712 USA jbrodbelt@cm.utexas.edu., Ahn YC; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin Austin TX 78712 USA walt.fast@austin.utexas.edu., Rivera DD; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin Austin TX 78712 USA walt.fast@austin.utexas.edu., Thomas PW; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin Austin TX 78712 USA walt.fast@austin.utexas.edu., Cheng Z; Department of Chemistry and Biochemistry, Miami University Oxford OH 45056 USA., Crowder MW; Department of Chemistry and Biochemistry, Miami University Oxford OH 45056 USA., Pratt RF; Department of Chemistry, Wesleyan University Middletown CT 06459 USA., Fast W; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas at Austin Austin TX 78712 USA walt.fast@austin.utexas.edu., Brodbelt JS; Department of Chemistry, University of Texas at Austin Austin TX 78712 USA jbrodbelt@cm.utexas.edu.

Publikováno v: Chemical science [Chem Sci] 2020 Aug 11; Vol. 11 (33), pp. 8999-9010. Date of Electronic Publication: 2020 Aug 11.

Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb.

Autor: Mayfield JE; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Irani S; Department of Chemical Engineering, University of Texas at Austin, Austin, United States., Escobar EE; Department of Chemistry, University of Texas at Austin, Austin, United States., Zhang Z; Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, United States., Burkholder NT; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Robinson MR; Department of Chemistry, University of Texas at Austin, Austin, United States., Mehaffey MR; Department of Chemistry, University of Texas at Austin, Austin, United States., Sipe SN; Department of Chemistry, University of Texas at Austin, Austin, United States., Yang W; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Prescott NA; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Kathuria KR; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States., Liu Z; Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, United States., Brodbelt JS; Department of Chemistry, University of Texas at Austin, Austin, United States., Zhang Y; Department of Molecular Biosciences, University of Texas at Austin, Austin, United States.; Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, United States.

Publikováno v: ELife [Elife] 2019 Aug 06; Vol. 8. Date of Electronic Publication: 2019 Aug 06.

Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line.

Autor: Meinke JL; Department of Molecular Biosciences , The University of Texas at Austin , Austin , Texas 78712 , United States., Mehaffey MR; Department of Chemistry , The University of Texas at Austin , Austin , Texas 78712 , United States., Wagner DT; Department of Molecular Biosciences , The University of Texas at Austin , Austin , Texas 78712 , United States., Sun N; Department of Molecular Biosciences , The University of Texas at Austin , Austin , Texas 78712 , United States., Zhang Z; Department of Chemistry , The University of Texas at Austin , Austin , Texas 78712 , United States., Brodbelt JS; Department of Chemistry , The University of Texas at Austin , Austin , Texas 78712 , United States., Keatinge-Clay AT; Department of Molecular Biosciences , The University of Texas at Austin , Austin , Texas 78712 , United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2018 Dec 21; Vol. 13 (12), pp. 3306-3314. Date of Electronic Publication: 2018 Nov 09.

Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.

Autor: Bergstrom A; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Katko A; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Adkins Z; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Hill J; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Cheng Z; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Burnett M; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Yang H; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Aitha M; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Mehaffey MR; Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States., Brodbelt JS; Department of Chemistry, University of Texas at Austin , Austin, Texas 78712, United States., Tehrani KHME; Department of Chemical Biology and Drug Discovery Utrecht Institute for Pharmaceutical Sciences, Utrecht University , Universiteitsweg 99, 3584 CG Utrecht, The Netherlands., Martin NI; Department of Chemical Biology and Drug Discovery Utrecht Institute for Pharmaceutical Sciences, Utrecht University , Universiteitsweg 99, 3584 CG Utrecht, The Netherlands., Bonomo RA; Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center , 10701 East Boulevard, Cleveland, Ohio 44106, United States., Page RC; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Tierney DL; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States., Fast W; Division of Chemical Biology and Medicinal Chemistry, College of Pharmacy, University of Texas , 107 W. Dean Keeton, Austin, Texas 78712, United States., Wright GD; Michael G DeGroote Institute for Infectious Disease and Department of Biochemistry and Biomedical Sciences, McMaster University , 1280 Main Street West, Hamilton, Ontario L8S4L8, Canada., Crowder MW; Department of Chemistry and Biochemistry, Miami University , 650 East High Street, Oxford, Ohio 45056, United States.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2018 Feb 09; Vol. 4 (2), pp. 135-145. Date of Electronic Publication: 2017 Nov 09.