Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Megumu Higaki"'
Autor:
Masahiro Kamono, Takahiko Mine, Akihiro Ueda, Akiko Taoda, Yusuke Kabeya, Tomohiro Matsumoto, Megumu Higaki, Atsushi Takagi, Terumitsu Hasebe, Eiseki Sohara
Publikováno v:
Journal of Medical Microbiology & Diagnosis.
Identifying the causative pathogens in patients with pyogenic vertebral osteomyelitis is important for optimizing antibiotic therapy. Thus, we examined patient characteristics and investigated the efficacy of the combined use of blood culture and ima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::519041fb04a52c629a4e4e81e30eafdd
https://doi.org/10.4172/2161-0703.1000261
https://doi.org/10.4172/2161-0703.1000261
Autor:
Takahiko Mine, Akiko Taoda, Tomohiro Matsumoto, Megumu Higaki, Terumitsu Hasebe, Masahiro Kamono, Toshihiko Hayashi
Publikováno v:
Cardiovascular and interventional radiology. 40(1)
To retrospectively describe the feasibility and efficacy of CT fluoroscopy-guided transsacral intervertebral drainage for pyogenic spondylodiscitis at the lumbosacral junction with a combination of two interventional radiological techniques-CT-guided
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1da9cfe5ef28b837261bd701119ee0
https://pubmed.ncbi.nlm.nih.gov/27558115
https://pubmed.ncbi.nlm.nih.gov/27558115
Autor:
Tomoko Kaburagi, Keiko Satoi, Megumu Higaki, Haruka Yoshino, Kazuto Sato, Keiji Nishimoto, Natsuko Sato-Mito, Hitomi Hayashi
Publikováno v:
Nutrition. 28:1109-1114
Objective We assessed whether disease activity was associated with dietary habits, nutritional status, adipokines, and oxidative stress in patients with rheumatoid arthritis. Methods The subjects were 37 patients with RA. The assessment of the nutrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776e5d1987e181d5bd9ace17370d5419
https://doi.org/10.1016/j.nut.2012.02.009
https://doi.org/10.1016/j.nut.2012.02.009
Publikováno v:
International Journal of Pharmaceutics. 385:170-175
We have prepared polymeric nanoparticles using a blend of poly(lactic acid) and monomethoxy-polyethyleneglycol(PEG)-polylactide block copolymer along with betamethasone disodium phosphate (BP). Nanoparticles have been screened for anti-inflammatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b6a77e655389a02bdddf97c75aa607
https://doi.org/10.1016/j.ijpharm.2009.10.025
https://doi.org/10.1016/j.ijpharm.2009.10.025
Autor:
Kanae Kodera, Tsutomu Ishihara, Megumu Higaki, Hideko Kanazawa, Yutaka Mizushima, Maoko Goto, Yasuko Murakami
Publikováno v:
Drug Delivery. 16:153-159
To achieve the effective intracellular delivery of siRNA and silence specific genes, various types of conjugates between cell-penetrating peptides (CPPs; Transportan, Penetratin, Tat) and cationic peptides were developed. Uptake, intracellular locali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ed37a78d56c1a287039e2c3bebd885
https://doi.org/10.1080/10717540902722774
https://doi.org/10.1080/10717540902722774
Publikováno v:
The Journal of Dermatology. 36:144-149
Psoriasis is a chronic inflammatory skin disease characterized by epidermal hyperproliferation and infiltration of inflammatory leukocytes. The aim of this study was to clarify the role of innate immunity involving dendritic cells (DC) and keratinocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa6bd06bd95819b66db1644416bb94a3
https://doi.org/10.1111/j.1346-8138.2009.00609.x
https://doi.org/10.1111/j.1346-8138.2009.00609.x
Publikováno v:
International Journal of Pharmaceutics. 365:200-205
Solid nanoparticles consisting of biodegradable polymers have emerged as a promising carrier for various drugs, but unfortunately the encapsulation of drugs remains challenging. In this study, a technique for encapsulation of water-soluble drugs in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206c6f3ae8346983daea2347fe65c166
https://doi.org/10.1016/j.ijpharm.2008.08.030
https://doi.org/10.1016/j.ijpharm.2008.08.030
Autor:
Megumu Higaki
Publikováno v:
Drug Delivery System. 24:394-401
臨床的に有用な薬剤であるステロイドをコンプライアンス・薬効の向上，および副作用の軽減のため高分子ナノキャリアーに封入した．ナノサイズによりEPR効果による炎症局所への標的
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6df6aa4ac6cc99e755a318e2c365df00
https://doi.org/10.2745/dds.24.394
https://doi.org/10.2745/dds.24.394
Autor:
Kotaro Matsunaga, Yasuhiro Asahina, Shozo Miyake, K. Ueda, Takanori Hosokawa, Masayuki Kurosaki, F. Doi, Hiroyuki Nakanishi, Megumu Higaki, N. Umeda, T. Kitamura, Kaoru Tsuchiya, M. Uchihara, Namiki Izumi
Publikováno v:
Journal of Viral Hepatitis. 14:396-403
This study investigated the molecular and pharmacokinetic mechanisms of the enhanced antiviral efficacy associated with pegylated interferon (PEG-IFN) alpha-2b and ribavirin. The study involved comparing the expression of serial double-stranded RNA-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ebc245e655aa3a08382359ab51bb0d
https://doi.org/10.1111/j.1365-2893.2006.00803.x
https://doi.org/10.1111/j.1365-2893.2006.00803.x
Autor:
Satoko Asano, Hirokazu Hamano, Hidenobu Aizawa, Yutaka Mizushima, Jong-Won Park, Yoshitsugu Harada, Shigeru Kurosawa, Megumu Higaki
Publikováno v:
Biosensors and Bioelectronics. 22:409-414
To detect dioxin using a quartz crystal microbalance (QCM) immunosensor, anti-2,3,7,8-tetrachloro-p-dibenzodioxin (TCDD) monoclonal antibodies (MAbs) were produced as types of IgG1 and IgM, with mono 6-(2,3,6,7-tetrachloroxanthene-9-ylidene) hexyl su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7367d4071a297c042b720580efe7af19
https://doi.org/10.1016/j.bios.2006.05.002
https://doi.org/10.1016/j.bios.2006.05.002