Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Megumi Yoshikawa"'
Publikováno v:
The Journal of organic chemistry. 81(1)
The highly regioselective hydroselenation of N-vinyl lactams has been revealed to successfully afford the corresponding N,Se-acetals as Markovnikov adducts. In the case of terminal N-vinyl lactams, Markovnikov-selective hydroselenation proceeds effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e6136f76739dee8de17a2b7ee9f4a2f
https://pubmed.ncbi.nlm.nih.gov/26618473
https://pubmed.ncbi.nlm.nih.gov/26618473
Autor:
J.N. Yue, Xiaomin Luo, Ding-An Zhou, C. Almeida, Akiko Ito, Shigeru Kohno, Valentina Lombardi, Hisahiro Yoshida, A. Maleddu, Yoji Ikegami, Kazumi Sano, R.S. Guo, Carlo Barone, E. Martín-Mazuelos, M.A. Pantaleo, M.C. Serrano, Jiayong Chen, Yoichi Nakamura, Yong-Chang Yang, A. Valverde, Koen De Vis, S. Fanti, Annamaria Piscazzi, Jian Li, Yi Zhang, Paolo Pedrazzoli, Giuseppe Daidone, Xiaoting Wu, Matteo Landriscina, Farheen Shah-Khan, Hiroshi Soda, Sung Yong Oh, J.Y. Li, Ilaria Schiavetto, Qi Hu, G. Samonis, Hyun Jin Kim, Megumi Yoshikawa, A.T. Zisiou, Probodh Shah, E. Mantadakis, Wen Liu, Z.W. Quan, Tae Hyo Kim, Yong Yuan, Giovanni Brandi, Ya-Li Zeng, Dai-Wen Xiao, Mauro Cignarelli, Lin Li, Benedetta Maggio, T. Anastasopoulos, Lili Fu, Alberto Fersini, Salvatore Siena, J. Pemán, D.P. Kofteridis, S. Maraki, Mikio Oka, Wen-Fang Huang, Jung Hun Kang, Daoming Liang, G. Notas, M. Farsad, Vera Basilico, Maria Valeria Raimondi, Gyeong-Won Lee, S. Fanello, Demetrio Raffa, Xishan Xiong, Maria Grazia Cusimano, Bo Huang, Stella Cascioferro, Annarita Fabiano, Domenico Schillaci, G. Biasco, Guo-Qiang Xu, M. Nannini, Changlin Mei, Liang-Min Chuan, Michele Santodirocco, Hoon Gu Kim, C. Castro, G. Papazoglou, Hong Liu, M. Di Battista, Y.Y. Qin, Hirofumi Nakano, Kurika Satake, S.G Li, G. Ercolani, Seigo Sawada
Publikováno v:
Chemotherapy. 54:I-VI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e857f2cbd6992ec17f23dd74c404152
https://doi.org/10.1159/000165691
https://doi.org/10.1159/000165691
Autor:
Mikio Oka, Kurika Satake, Hirofumi Nakano, Hiroshi Soda, Yoji Ikegami, Seigo Sawada, Hisahiro Yoshida, Megumi Yoshikawa, Yoichi Nakamura, Kazumi Sano, Akiko Ito, Shigeru Kohno
Publikováno v:
Chemotherapy. 54:485-491
Background: Gefitinib competes with topoisomerase I inhibitors at drug efflux pumps in vitro. We evaluated the effects of oral gefitinib on pharmacokinetic parameters of orally coadministered irinotecan. Methods: We measured the serum pharmacokinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0e1245423e14cf8f0ee943f9c46651
https://doi.org/10.1159/000159625
https://doi.org/10.1159/000159625
Autor:
Kurita Satake, Hisahiro Yoshida, Megumi Yoshikawa, Shinzo Tanabe, Toshihisa Ishikawa, Shinya Hayasaka, Yoji Ikegami, Kazumi Sano, Seigo Sawada
Publikováno v:
Journal of Chromatography B. 795:25-34
SN-38 (7-ethyl-10-hydroxycamptothecin) is an active metabolite derived from the semi-synthetic compound camptothecin (CPT) named Irinotecan (CPT-11). The antitumor activity of SN-38 is 1000-fold more potent than the parent CPT-11. Fourteen new deriva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1174d2949ebfb0e1ca9818e9cbdf2ba
https://doi.org/10.1016/s1570-0232(03)00485-9
https://doi.org/10.1016/s1570-0232(03)00485-9
Autor:
Mikio Oka, Kunihiko Murase, Junji Tsurutani, Hisahiro Yoshida, Katsumi Nakatomi, Douglas D. Ross, Yoichi Nakamura, Yoji Ikegami, Shigeru Kohno, Megumi Yoshikawa, Yohei Mizuta, Seiji Doi, Takeshi Kitazaki, Hiroshi Soda, Ken Shiozawa
Publikováno v:
International Journal of Cancer. 108:146-151
Breast cancer resistance protein (BCRP/ABCG2) of an ATP-binding cassette half-transporter confers resistance against mitoxantrone and camptothecin derivatives of topotecan and irinotecan. Novobiocin, a coumermycin antibiotic, is known to enhance anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be09555e951ee1f0cf60e65ed6d5905a
https://doi.org/10.1002/ijc.11528
https://doi.org/10.1002/ijc.11528
Autor:
Toshihisa Ishikawa, Shinya Hayasaka, Katsumi Nakatomi, Hiroshi Soda, Shigeru Kohno, Yoji Ikegami, Mikio Oka, Ken Shiozawa, Megumi Yoshikawa, Shinzo Tanabe, Shigeru Kawabata, Kazumi Sano
Publikováno v:
Biochemical and Biophysical Research Communications. 288:827-832
Overexpression of breast cancer resistance protein (BCRP) ABCG2 reportedly confers cancer cell resistance to camptothecin-based anticancer drugs, such as topotecan and 7-ethyl-10-hydroxycamptothecin (SN-38: the active metabolite of irinotecan). We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e23b88d5077c632ad43f509535ede9
https://doi.org/10.1006/bbrc.2001.5850
https://doi.org/10.1006/bbrc.2001.5850
Publikováno v:
Drug Metabolism and Pharmacokinetics. 16:353-363
In the last decade of the 20th century, the development of high throughput screening (HTS) and combinatorial chemistry technologies accelerated the drug discovery process. In the 21st century, emerging genomic technologies (i.e., bioinformatics, func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c30f484c4b736f58b6e4fc1646be7b9
https://doi.org/10.2133/dmpk.16.353
https://doi.org/10.2133/dmpk.16.353
Autor:
David M. Hirst, Megumi Yoshikawa
Publikováno v:
Chemical Physics Letters. 244:258-262
Preliminary ab initio MRCI potential-energy curves are presented for the low-lying doublet states of the molecular ions GaF+ and GaCl+ correlating with the dissociation asymptotes Ga+ (1S, 3P) + F, C (2P). The two lowest 2Σ+ states are bound and ari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a737ab29ffc50d40efbea98daf3bc572
https://doi.org/10.1016/0009-2614(95)00916-r
https://doi.org/10.1016/0009-2614(95)00916-r
Autor:
Yasukouchi T, Masahiro Satoh, Shoichi Nakagawa, Masahiro Ieko, Sakurama S, Megumi Yoshikawa, Akira Sagawa
Publikováno v:
American Journal of Hematology. 35:26-31
Marked thrombocytopenia developed during pregnancy in both identical twins mothers who had systemic lupus erythematosus (SLE) and also type IIB von Willebrand's disease (vWD). The proband's platelet count decreased in the third trimester of pregnancy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc3c426e6298c8d2e7598f5684f4700
https://doi.org/10.1002/ajh.2830350107
https://doi.org/10.1002/ajh.2830350107
Autor:
Ken Shiozawa, Shigeru Kohno, Seiji Doi, Megumi Yoshikawa, Hiroshi Soda, Takeshi Kitazaki, Junji Tsurutani, Hisahiro Yoshida, Mikio Oka, Yoichi Nakamura, Yoji Ikegami, Akiko Itoh, Katsumi Nakatomi
Publikováno v:
Cancer research. 65(4)
Gefitinib (“Iressa”, ZD1839) is an orally active, selective epidermal growth factor receptor tyrosine kinase inhibitor, and the single agent is clinically effective in non–small cell lung cancer. Although gefitinib combined with various cytotox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df202276ba1ea3db39dc31079d11adbc
https://pubmed.ncbi.nlm.nih.gov/15735043
https://pubmed.ncbi.nlm.nih.gov/15735043