Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Megumi Kishimoto-Urata"'
Autor:
Megumi Kishimoto‐Urata, Shinji Urata, Hironobu Nishijima, Shintaro Baba, Yoko Fujimaki, Kenji Kondo, Tatsuya Yamasoba
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 5, Pp 1189-1195 (2023)
Abstract Objective To investigate whether machine learning (ML)‐based algorithms, namely logistic regression (LR), random forest (RF), k‐nearest neighbor (k‐NN), and gradient‐boosting decision tree (GBDT), utilizing early post‐onset paramet
Externí odkaz:
https://doaj.org/article/59f4cff928864967923ab466ead167e7
Autor:
Megumi Kishimoto-Urata, Shinji Urata, Ryoji Kagoya, Fumiaki Imamura, Shin Nagayama, Rachel A. Reyna, Junki Maruyama, Tatsuya Yamasoba, Kenji Kondo, Sanae Hasegawa-Ishii, Slobodan Paessler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the olfactory sensory neurons, prolonged activation of glial cells in the olfactory bulb,
Externí odkaz:
https://doaj.org/article/12fd7fed7a19441e9c5c48c110348f87
Autor:
Rachel A. Reyna, Megumi Kishimoto-Urata, Shinji Urata, Tomoko Makishima, Slobodan Paessler, Junki Maruyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a pandemic affecting billions of people worldwide. Apart from the extreme global economic impact, the pandemic will likely have a lasting impact through long-ter
Externí odkaz:
https://doaj.org/article/651bb99cbac24de89e0f4b794c2dc9b0
Autor:
Junki Maruyama, Rachel A Reyna, Megumi Kishimoto-Urata, Shinji Urata, John T Manning, Nantian Harsell, Rebecca Cook, Cheng Huang, Janko Nikolich-Zugich, Tomoko Makishima, Slobodan Paessler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010557 (2022)
Lassa virus (LASV) is the causative agent of Lassa fever (LF), which presents as a lethal hemorrhagic disease in severe cases. LASV-induced hearing loss in survivors is a huge socioeconomic burden, however, the mechanism(s) leading to hearing loss is
Externí odkaz:
https://doaj.org/article/c6d8f5e163c24ea4afd188ae99ac0294
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1469 (2022)
Oxygen metabolism in the mitochondria is essential for biological activity, and reactive oxygen species (ROS) are produced simultaneously in the cell. Once an imbalance between ROS production and degradation (oxidative stress) occurs, cells are damag
Externí odkaz:
https://doaj.org/article/2ccc7f2cc15a4c57a5a826036962f3e2
Publikováno v:
Journal of Japan Association on Odor Environment. 53:141-146
Autor:
Ryoji Kagoya, Tatsuya Yamasoba, Kenji Kondo, Shu Kikuta, Yuya Shimizu, Megumi Kishimoto-Urata
Publikováno v:
Allergy. 76:1432-1442
Background Eosinophilic chronic rhinosinusitis (ECRS) is a chronic inflammatory disease, characterized by eosinophilic infiltration, T-helper type 2 (Th2-type) response, and olfactory dysfunction. A master regulator of Th2-type inflammation, thymic s
Autor:
Shinji Urata, Rachel A. Reyna, Junki Maruyama, Slobodan Paessler, Tomoko Makishima, Megumi Kishimoto-Urata
Publikováno v:
Scientific Reports
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a pandemic affecting millions of people worldwide. Apart from the extreme global economic impact, the pandemic will likely have a lasting impact through long-term sequela
Autor:
Shin Nagayama, Kenji Kondo, Megumi Kishimoto-Urata, Sanae Hasegawa-Ishii, Fumiaki Imamura, Slobodan Paessler, Rachel A. Reyna, Junki Maruyama, Tatsuya Yamasoba, Shinji Urata, Ryoji Kagoya
The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the olfactory sensory neurons, prolonged activation of glial cells in the olfactory bulb, and a de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e2861ef6a5d71c288796b0b3185d406
https://doi.org/10.1101/2021.11.04.467274
https://doi.org/10.1101/2021.11.04.467274
Autor:
Rachel A. Sattler, Shinji Urata, Megumi Kishimoto-Urata, Slobodan Paessler, Nantian Lin, Junki Maruyama, Tatsuya Yamasoba, Tomoko Makishima, Rebecca S. Cook
Publikováno v:
ACS Chemical Neuroscience
Olfactory dysfunction is one of the most frequent and specific symptoms of coronavirus disease 2019 (COVID-19). Information on the damage and repair of the neuroepithelium and its impact on olfactory function after COVID-19 is still incomplete. While