Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Megumi Kishimoto"'
Autor:
Megumi Kishimoto‐Urata, Shinji Urata, Hironobu Nishijima, Shintaro Baba, Yoko Fujimaki, Kenji Kondo, Tatsuya Yamasoba
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 8, Iss 5, Pp 1189-1195 (2023)
Abstract Objective To investigate whether machine learning (ML)‐based algorithms, namely logistic regression (LR), random forest (RF), k‐nearest neighbor (k‐NN), and gradient‐boosting decision tree (GBDT), utilizing early post‐onset paramet
Externí odkaz:
https://doaj.org/article/59f4cff928864967923ab466ead167e7
Autor:
Megumi Kishimoto, Mayumi Komine, Koji Kamiya, Junichi Sugai, Aya Kuwahara, Makiko Mieno, Mamitaro Ohtsuki
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 6, Pp 1347-1360 (2023)
Abstract Introduction This study aimed to retrospectively examine the drug survival of tumor necrosis factor (TNF)-alpha inhibitors and switched subsequent biologic agents after discontinuation of TNF inhibitors. Methods This real-world setting study
Externí odkaz:
https://doaj.org/article/887e69b2209d4ab787684aca16a0167e
Autor:
Megumi Kishimoto-Urata, Shinji Urata, Ryoji Kagoya, Fumiaki Imamura, Shin Nagayama, Rachel A. Reyna, Junki Maruyama, Tatsuya Yamasoba, Kenji Kondo, Sanae Hasegawa-Ishii, Slobodan Paessler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The impact of SARS-CoV-2 on the olfactory pathway was studied over several time points using Syrian golden hamsters. We found an incomplete recovery of the olfactory sensory neurons, prolonged activation of glial cells in the olfactory bulb,
Externí odkaz:
https://doaj.org/article/12fd7fed7a19441e9c5c48c110348f87
Autor:
Rachel A. Reyna, Megumi Kishimoto-Urata, Shinji Urata, Tomoko Makishima, Slobodan Paessler, Junki Maruyama
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for a pandemic affecting billions of people worldwide. Apart from the extreme global economic impact, the pandemic will likely have a lasting impact through long-ter
Externí odkaz:
https://doaj.org/article/651bb99cbac24de89e0f4b794c2dc9b0
Autor:
Junki Maruyama, Rachel A Reyna, Megumi Kishimoto-Urata, Shinji Urata, John T Manning, Nantian Harsell, Rebecca Cook, Cheng Huang, Janko Nikolich-Zugich, Tomoko Makishima, Slobodan Paessler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010557 (2022)
Lassa virus (LASV) is the causative agent of Lassa fever (LF), which presents as a lethal hemorrhagic disease in severe cases. LASV-induced hearing loss in survivors is a huge socioeconomic burden, however, the mechanism(s) leading to hearing loss is
Externí odkaz:
https://doaj.org/article/c6d8f5e163c24ea4afd188ae99ac0294
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1469 (2022)
Oxygen metabolism in the mitochondria is essential for biological activity, and reactive oxygen species (ROS) are produced simultaneously in the cell. Once an imbalance between ROS production and degradation (oxidative stress) occurs, cells are damag
Externí odkaz:
https://doaj.org/article/2ccc7f2cc15a4c57a5a826036962f3e2
Autor:
Megumi Kishimoto, Mayumi Komine, Miho Sashikawa-Kimura, Tuba Musarrat Ansary, Koji Kamiya, Junichi Sugai, Makiko Mieno, Hirotoshi Kawata, Ryutaro Sekimoto, Noriyoshi Fukushima, Mamitaro Ohtsuki
Publikováno v:
Diagnostics, Vol 11, Iss 10, p 1903 (2021)
Activation of signal transducer and activator of transcription (STAT)3 has been reported in many cancers. It is also well known that STAT3 is activated in skin lesions of psoriasis, a chronic skin disease. In this study, to ascertain whether patients
Externí odkaz:
https://doaj.org/article/91d7b55f456b4b3b995aaf5097403756
Publikováno v:
Case Reports in Otolaryngology, Vol 2018 (2018)
Introduction. We report a modification of the maxillary swing approach to remove a palatal tumor while preserving the anterior alveolar area. Methods. Case report using clinical records. Results. The patient was a 54-year-old male. TNM grade was T4bN
Externí odkaz:
https://doaj.org/article/003e933ed28a489ebf5a843bada81fd7
Autor:
Megumi Kishimoto, Masaya Akashi, Kazuyuki Tsuji, Junya Kusumoto, Shungo Furudoi, Yasuyuki Shibuya, Yumiko Inui, Kimikazu Yakushijin, Shinichiro Kawamoto, Atsuo Okamura, Hiroshi Matsuoka, Takahide Komori
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182021 (2017)
D-index which combines the intensity and duration of neutropenia is reported as a tool for evaluating the dynamics of neutropenia. This study aimed to analyze the relationship between D-index and oral complications (i.e., oral mucositis [OM] and odon
Externí odkaz:
https://doaj.org/article/971d0a5995be4038b273c4c92bf0061e
Publikováno v:
The Journal of Dermatology.