Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Megumi, Watanabe"'
Autor:
Araya Umetsu, Megumi Watanabe, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro
Publikováno v:
FEBS Open Bio, Vol 14, Iss 12, Pp 2026-2037 (2024)
The TGF‐β superfamily plays a pivotal role in the regulation of adipogenesis, but little is known about the potential differential role of the three isoforms of TGF‐β, TGF‐β‐1~3. To further elucidate their role, two‐dimensionally (2D) an
Externí odkaz:
https://doaj.org/article/0f2d40a97cae4dd99e7153c937ad7484
Autor:
Adityakrisna Yoshi Putra Wigianto, Megumi Watanabe, Yuki Iwawaki, Takaharu Goto, Tamaki Otsuki, Tetsuo Ichikawa
Publikováno v:
Hygiene, Vol 4, Iss 1, Pp 93-102 (2024)
This in vitro study aimed to confirm the effect of the additional features of Kirei Keep Light (KKL), a commercial UV-C irradiation system that was originally created for coating the surface of removable dentures with photoreactive 2-methacryloyloxye
Externí odkaz:
https://doaj.org/article/a25b8e62a1a04aa89bb2cc11864a81f7
Autor:
Megumi Watanabe, Tatsuya Sato, Toshiyuki Yano, Megumi Higashide, Toshifumi Ogawa, Nami Nishikiori, Masato Furuhashi, Hiroshi Ohguro
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2604 (2024)
Background/Objectives: Mammalian target of rapamycin (mTOR) inhibition may have been suggested to have a beneficial effect on the glaucomatous human trabecular meshwork (HTM). To study the effects of the mTOR inhibitors rapamycin (Rapa) and Torin1 on
Externí odkaz:
https://doaj.org/article/7d6afdd7daa54d8bb6dc856c439e73b5
Publikováno v:
Ecology and Evolution, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Wildlife observation is a popular activity, and sightings of rare or difficult‐to‐find animals are often highly desired. However, predicting the sighting probabilities of these animals is a challenge for many observers, and it may only b
Externí odkaz:
https://doaj.org/article/d203017182e84c2d85b1661ed7476f60
Autor:
Megumi Higashide, Megumi Watanabe, Tatsuya Sato, Toshifumi Ogawa, Araya Umetsu, Soma Suzuki, Masato Furuhashi, Hiroshi Ohguro, Nami Nishikiori
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2228 (2024)
Objectives: To study the effects of all-trans retinoic acid (ATRA) on TGF-β2-induced effects of human retinal pigment epithelium cells under normoxia and hypoxia conditions. Methods: Two-dimensionally (2D) and three-dimensionally (3D) cultured ARPE1
Externí odkaz:
https://doaj.org/article/3971cfab9a1f400e91cdbf409217c15b
Autor:
Hiroshi Ohguro, Megumi Watanabe, Tatsuya Sato, Nami Nishikiori, Araya Umetsu, Megumi Higashide, Toshiyuki Yano, Hiromu Suzuki, Akihiro Miyazaki, Kohichi Takada, Hisashi Uhara, Masato Furuhashi, Fumihito Hikage
Publikováno v:
Cells, Vol 13, Iss 18, p 1549 (2024)
Cell culture methods are indispensable strategies for studies in biological sciences and for drug discovery and testing. Most cell cultures have been developed using two-dimensional (2D) culture methods, but three-dimensional (3D) culture techniques
Externí odkaz:
https://doaj.org/article/009e28d5818a4aa78f74be027397bc70
Autor:
Nami Nishikiori, Tatsuya Sato, Toshifumi Ogawa, Megumi Higashide, Araya Umetsu, Soma Suzuki, Masato Furuhashi, Hiroshi Ohguro, Megumi Watanabe
Publikováno v:
Bioengineering, Vol 11, Iss 6, p 581 (2024)
To characterize transforming growth factor-β (TGF-β) isoform (TGF-β1~3)-b’s biological effects on the human retinal pigment epithelium (RPE) under normoxia and hypoxia conditions, ARPE19 cells cultured by 2D (two-dimensional) and 3D (three-dimen
Externí odkaz:
https://doaj.org/article/4698e04ef0ac4aa2b7fdc55c651ff9f4
Autor:
Hiroshi Ohguro, Megumi Watanabe, Tatsuya Sato, Nami Nishikiori, Araya Umetsu, Megumi Higashide, Toshifumi Ogawa, Masato Furuhashi
Publikováno v:
Bioengineering, Vol 11, Iss 6, p 584 (2024)
The purpose of the current study was to elucidate the physiological roles of intraocularly present fatty acid-binding protein 4 (FABP4). Using four representative intraocular tissue-derived cell types, including human non-pigmented ciliary epithelium
Externí odkaz:
https://doaj.org/article/7ba450bf3a154a75a70e1b9ad95cdad4
Autor:
Megumi Watanabe, Yuri Tsugeno, Tatsuya Sato, Megumi Higashide, Nami Nishikiori, Araya Umetsu, Toshifumi Ogawa, Masato Furuhashi, Hiroshi Ohguro
Publikováno v:
Life, Vol 14, Iss 6, p 770 (2024)
Background: Although lysophosphatidic acid (LPA) is known to have multiple pathophysiological roles, its contributions to ocular tissues, especially conjunctival fibrogenesis, remain to be elucidated. Methods: To study this issue, the effects of LPA
Externí odkaz:
https://doaj.org/article/b8554f4b0d5e4cf8b289212638653339
Autor:
Megumi Watanabe, Tatsuya Sato, Araya Umetsu, Toshifumi Ogawa, Nami Nishikiori, Megumi Suzuki, Masato Furuhashi, Hiroshi Ohguro
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1165 (2024)
To investigate the biological significance of Rho-associated coiled-coil-containing protein kinase (ROCK) 2 in the human trabecular meshwork (HTM), changes in both metabolic phenotype and gene expression patterns against a specific ROCK2 inhibitor KD
Externí odkaz:
https://doaj.org/article/510c4eac2fe64ff3b93fe2ab9b804fd2