Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Megumi, Kawamoto"'
Autor:
Kaede Baba, Megumi Kawamoto, Kanako Mamishin, Mao Uematsu, Hikari Kiyohara, Akira Hirota, Nobuyuki Takahashi, Misao Fukuda, Shota Kusuhara, Hiromichi Nakajima, Chikako Funasaka, Takehiro Nakao, Chihiro Kondoh, Kenichi Harano, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Toshikatsu Kawasaki, Toru Mukohara
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12095-12105 (2023)
Abstract Background Since it was first reported in December 2019, coronavirus disease 2019 (COVID‐19) spread rapidly across the globe resulting in a pandemic. As of August 2022, seven outbreak peaks have been confirmed in Tokyo, and the numbers of
Externí odkaz:
https://doaj.org/article/c0255b117bae403e9d5e854df13ba152
Autor:
Chikako Funasaka, Yoichi Naito, Shota Kusuhara, Takehiro Nakao, Hiromichi Nakajima, Megumi Kawamoto, Kaede Baba, Kanako Mamishin, Chihiro Kondoh, Kenichi Harano, Nobuaki Matsubara, Ako Hosono, Tomoaki Sasaki, Toshikatsu Kawasaki, Toru Mukohara
Publikováno v:
Japanese Journal of Clinical Oncology. 53:105-114
Background Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors are the standard treatment for advanced hormone receptor-positive breast cancer. Although interstitial lung disease is a rare (1–3.3%) but serious adverse event associated with CDK4/6 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1104059874437cc3479bc7074f648fcc
https://doi.org/10.1093/jjco/hyac168
https://doi.org/10.1093/jjco/hyac168
PDF file - 58 KB, Cytotoxic activity of Her2-lytic hybrid peptide to cancer cells after the incubation with serum protein solution. HER2-lytic hybrid peptide was mixed with serum sample which was prepared from FBS for 0, 3, 6, 24 h, and then the mixt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1b16935efd9d59c67dd3b972baeb9c
https://doi.org/10.1158/1535-7163.22497672.v1
https://doi.org/10.1158/1535-7163.22497672.v1
PDF file - 123 KB, Hematology and serum metabolic panel. Mean�}SD (n=3 mice/group�j. Statistical values are between the 2 groups. AST; aspartate aminotransferase, ALT; alanine aminotransferase, ALP alkaline phosphatase, LDH; lactate dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0270b10a486895e93546379967fe7771
https://doi.org/10.1158/1535-7163.22497669
https://doi.org/10.1158/1535-7163.22497669
HER2 is a transmembrane oncoprotein encoded by the HER2/neu gene and is overexpressed in approximately 20% to 30% of breast cancers. We have recently designed a novel class of drug, the hybrid peptide, which is chemically synthesized and is composed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c79cd1da453f4864b340829546459ba
https://doi.org/10.1158/1535-7163.c.6535683.v1
https://doi.org/10.1158/1535-7163.c.6535683.v1
PDF file - 64 KB, Effect on cell viability of anti-HER2 antibody and knockdown of HER2 by siRNA. (A) BT-474 and MDA-MB-231 cells were incubated with increasing concentrations of anti-HER2 monoclonal antibody for 3 h, and cytotoxicity was assessed usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323d7538dfb466646a120fe36542e69b
https://doi.org/10.1158/1535-7163.22497684.v1
https://doi.org/10.1158/1535-7163.22497684.v1
PDF file - 56 KB, Effect of Her2-lytic hybrid peptide on cell viability of H9c2 cells. H9c2 cells were cultured with various concentrations of HER2-lytic hybrid peptide as indicated for 72 h, and cell viability was assessed using WST-8 reagent as des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2ac42d98a5c7fb4e2789654b4832987
https://doi.org/10.1158/1535-7163.22497675
https://doi.org/10.1158/1535-7163.22497675
PDF file - 39 KB, Cell viability of breast cancer cell lines treated with HER2-lytic hybrid peptide at half the IC50 dose for 3 h. Breast cancer cell lines were treated with HER2-lytic hybrid peptide for 3 h at half the IC50 dose (SK-BR-3, 3.0 ��
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134a3260e1bdf57c40efcc2909305a2e
https://doi.org/10.1158/1535-7163.22497678
https://doi.org/10.1158/1535-7163.22497678
PDF file - 61 KB, Single-dose toxicity study of HER2-lytic in mice. BALB/c mice were received HER2-lytic peptide as intravenous injections (50 ��l/injection).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6473730a1e5fa9cd9f5e2776568a76
https://doi.org/10.1158/1535-7163.22497666.v1
https://doi.org/10.1158/1535-7163.22497666.v1
PDF file - 41 KB, Effect of HER2 binding peptide on breast cancer cell lines. Cells were seeded onto 96-well plates at 3�~103 cells per well and incubated for 24 h. The cells were then incubated with increasing concentrations of the HER2-binding pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376bca359e1f8ece1cccf6221168c74d
https://doi.org/10.1158/1535-7163.22497681
https://doi.org/10.1158/1535-7163.22497681