Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Megias-Vericat JE"'
1
Common Genetic Variants in ABO and CLEC4M Modulate the Pharmacokinetics of Recombinant FVIII in Severe Hemophilia A Patients
Autor: Garcia-Martínez I, Borràs N, Martorell M, Parra R, Altisent C, Ramírez L, Álvarez-Román MT, Nuñez R, Megias-Vericat JE, Corrales I, Alonso S, Vidal F
Publikováno v: THROMBOSIS AND HAEMOSTASIS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
The pharmacokinetic (PK) response of severe hemophilia A (HA) patients to infused factor VIII (FVIII) shows substantial variability. Several environmental and genetic factors are associated with changes in FVIII plasma levels and infused FVIII PK. Ba
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::1bcab0f49cb0a4ebbf2225b3a2073aa5
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=13144
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2
IDH1-mutated relapsed or refractory AML: current challenges and future prospects
Autor: Megias-Vericat, JE, Ballesta-Lopez, O, Barragan, E, Montesinos, P
Publikováno v: BLOOD AND LYMPHATIC CANCER-TARGETS AND THERAPY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Juan Eduardo Megías-Vericat,1 Octavio Ballesta-López,1 Eva Barragán,2,3 Pau Montesinos2,31Servicio de Farmacia, Área del Medicamento, Hospital Universitari i Politècnic La Fe, Valencia, Spain; 2Servicio de Hematología y Hemoterapia, Hospital Un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d9c64b9db0ec20ed691ef37bc4fd082
https://www.dovepress.com/idh1-mutated-relapsed-or-refractory-aml-current-challenges-and-future--peer-reviewed-article-BLCTT
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3
Daunorubicin and cytarabine for certain types of poor-prognosis acute myeloid leukemia: a systematic literature review
Autor: Megias-Vericat, JE, Martinez-Cuadron, D, Sanz, MA, Poveda, JL, Montesinos, P
Publikováno v: Expert Review of Clinical Pharmacology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Introduction: Induction chemotherapy based on anthracyclines and cytarabine (Ara-C) combination remains the standard of care for acute myeloid leukemia (AML) patients who are considered candidate for intensive and curative approaches. However, the to
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::0861c768ccd2f8f6cac9f0b16535e91d
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=10138
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5
Pharmacogenetics of Metabolic Genes of Anthracyclines in Acute Myeloid Leukemia
Autor: Megias-Vericat, JE, Martinez-Cuadron, D, Herrero, MJ, Alino, SF, Poveda, JL, Sanz, MA, Montesinos, P
Publikováno v: CURRENT DRUG METABOLISM
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Background: Anthracyclines in combination with cytarabine have been the standard therapy for acute myeloid leukemia (AML) for decades with high efficacy. However, the majority of patients will show initial resistance or will relapse after initial com
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::ae8b15ab75e21bc7fed34efda6c2c9aa
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=6932
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6
Impact of NADPH oxidase functional polymorphisms in acute myeloid leukemia induction chemotherapy
Autor: Megias-Vericat, JE, Montesinos, P, Herrero, MJ, Moscardo, F, Boso, V, Rojas, L, Martinez-Cuadron, D, Rodriguez-Veiga, R, Sendra, L, Cervera, J, Poveda, JL, Sanz, MA, Aliño SF
Publikováno v: PHARMACOGENOMICS JOURNAL
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Efficacy and toxicity of anthracycline treatment in acute myeloid leukemia (AML) is mediated by reactive oxygen species (ROS). NADPH oxidase is the major endogenous source of ROS and a key mediator of oxidative cardiac damage. The impact of NADPH oxi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::da0650ccb6791afae6039c43a3c312e9
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7239
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7
Salvage regimens using conventional chemotherapy agents for relapsed/refractory adult AML patients: a systematic literature review
Autor: Megias-Vericat, JE, Martinez-Cuadron, D, Sanz, MA, Montesinos, P
Publikováno v: ANNALS OF HEMATOLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Prognosis in relapsed and refractory acute myeloid leukemia (R/R AML) patients is dismal, with no satisfactory and standard salvage chemotherapy regimen. We performed a systematic review in order to analyze the clinical outcomes reported with convent
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::f8924138f95f55ef3117963ba03c931b
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7846
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8
Early experience with compassionate use of 2 hydroxypropyl-beta-cyclodextrin for Niemann-Pick type C disease: review of initial published cases
Autor: Megias-Vericat, JE, Garcia-Robles, A, Company-Albir, MJ, Fernandez-Megia, MJ, Perez-Miralles, FC, Lopez-Briz, E, Casanova, B, Poveda, JL
Publikováno v: NEUROLOGICAL SCIENCES
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Niemann-Pick type C (NP-C) is a rare neurodegenerative disorder. Management is mainly supportive and symptomatic. The investigational use of 2-hydroxypropyl-beta-cyclodextrin (HP-beta-CD) showed a promising role in treating NP-C, although efficacy an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::e8a0a3fcaa4211e47a8808cb08cb0300
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=4894
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10
Impact of novel polymorphisms related to cytotoxicity of cytarabine in the induction treatment of acute myeloid leukemia
Autor: Megias-Vericat, JE, Montesinos, P, Herrero, MJ, Moscardo, F, Boso, V, Martinez-Cuadron, D, Poveda, JL, Sanz, MA, Aliño SF
Publikováno v: PHARMACOGENETICS AND GENOMICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Several novel single nucleotide polymorphisms (SNPs) involved in cytarabine cytotoxicity and related to clinical outcomes have been reported recently in a series of 232 pediatric patients with acute myeloid leukemia (AML). We report the first adult A
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::7c93403286b1db1efb8bae1178d12941
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=7240
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