Zobrazeno 1 - 10 of 111 pro vyhledávání: '"Meghana V Trivedi"'
1
Akademický článek
Comparing the effects of various β-blockers on cardiovascular mortality in breast cancer patients
Autor: Mantasha Tabassum, Soumya G. Chikermane, Camille Johnson, Noor M. Abdulkareem, Elisabeth M. Wang, Michael L. Johnson, Meghana V. Trivedi
Publikováno v: Cardio-Oncology, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Background Cardiovascular (CV) disease is a leading cause of death in breast cancer (BC) patients due to the increased age and treatments. While individual β-blockers have been investigated to manage CV complications, various β-blockers ha
Externí odkaz: https://doaj.org/article/d68bdaebd5e34cefa3a68098abf8e26f
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2
Akademický článek
High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer
Autor: Xiaoyong Fu, Resel Pereira, Chia-Chia Liu, Carmine De Angelis, Martin J. Shea, Sarmistha Nanda, Lanfang Qin, Tamika Mitchell, Maria L. Cataldo, Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Mario Giuliano, Carolina Gutierrez, Balázs Győrffy, Meghana V. Trivedi, Ofir Cohen, Nikhil Wagle, Agostina Nardone, Rinath Jeselsohn, Mothaffar F. Rimawi, C. Kent Osborne, Rachel Schiff
Publikováno v: Cell Reports, Vol 42, Iss 8, Pp 112821- (2023)
Summary: Aberrant activation of the forkhead protein FOXA1 is observed in advanced hormone-related cancers. However, the key mediators of high FOXA1 signaling remain elusive. We demonstrate that ectopic high FOXA1 (H-FOXA1) expression promotes estrog
Externí odkaz: https://doaj.org/article/9ae29d74241a427e80d1e8022dc30c52
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3
Akademický článek
NPY1R exerts inhibitory action on estradiol-stimulated growth and predicts endocrine sensitivity and better survival in ER-positive breast cancer
Autor: Raksha Bhat, Hariprasad Thangavel, Noor Mazin Abdulkareem, Suhas Vasaikar, Carmine De Angelis, Leon Bae, Maria Letizia Cataldo, Sarmistha Nanda, Xiaoyong Fu, Bing Zhang, Rachel Schiff, Meghana V. Trivedi
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract G Protein-Coupled Receptors (GPCRs) represent the largest superfamily of cell-surface proteins. However, the expression and function of majority of GPCRs remain unexplored in breast cancer (BC). We interrogated the expression and phosphoryla
Externí odkaz: https://doaj.org/article/f573b7bda516414bb4b2dfb6151cfce9
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4
Akademický článek
Screening of GPCR drugs for repurposing in breast cancer
Autor: Noor Mazin Abdulkareem, Raksha Bhat, Reid T. Powell, Soumya Chikermane, Soham Yande, Lisa Trinh, Hala Y. Abdelnasser, Mantasha Tabassum, Alexis Ruiz, Mary Sobieski, Nghi D. Nguyen, Jun Hyoung Park, Camille A. Johnson, Benny A. Kaipparettu, Richard A. Bond, Michael Johnson, Clifford Stephan, Meghana V. Trivedi
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
Drug repurposing can overcome both substantial costs and the lengthy process of new drug discovery and development in cancer treatment. Some Food and Drug Administration (FDA)-approved drugs have been found to have the potential to be repurposed as a
Externí odkaz: https://doaj.org/article/33621225788f4f8c9b9e070922e70999
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5
Akademický článek
Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis
Autor: Arturo B. Ramirez, Raksha Bhat, Debashish Sahay, Carmine De Angelis, Hariprasad Thangavel, Sina Hedayatpour, Lacey E. Dobrolecki, Agostina Nardone, Mario Giuliano, Chandandeep Nagi, Mothaffar Rimawi, C. Kent Osborne, Michael T. Lewis, Jackie L. Stilwell, Eric P. Kaldjian, Rachel Schiff, Meghana V. Trivedi
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Breast cancer patient-derived xenograft (BC-PDX) models represent a continuous and reproducible source of circulating tumor cells (CTCs) for studying their role in tumor biology and metastasis. We have previously shown the utility
Externí odkaz: https://doaj.org/article/cda25575e8d7448795627f419d53ae17
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