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pro vyhledávání: '"Meghan Wilkinson"'
Autor:
Molly C. McNamara, Aaron M. Hosios, Margaret E. Torrence, Ting Zhao, Cameron Fraser, Meghan Wilkinson, David J. Kwiatkowski, Elizabeth P. Henske, Chin-Lee Wu, Kristopher A. Sarosiek, Alexander J. Valvezan, Brendan D. Manning
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105458- (2022)
Summary: mTORC1 is aberrantly activated in cancer and in the genetic tumor syndrome tuberous sclerosis complex (TSC), which is caused by loss-of-function mutations in the TSC complex, a negative regulator of mTORC1. Clinically approved mTORC1 inhibit
Externí odkaz:
https://doaj.org/article/1546eb080b7a4a7f9f6f0f9c3783ba12
