Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Meghan Towers"'
Autor:
Hossein B. Askari, Raymond J. Patch, Wing S. Cheung, Hui Huang, Derek A. Beauchamp, Jyotsna Kasturi, Meghan Towers, Jianying Liu, Bao-Ping Zhao, Sharmila Patel, Dionisios Rentzeperis, Micheal Gaul, Mark R. Player, Guozhang Xu, John G. Geisler
Publikováno v:
European Journal of Medicinal Chemistry. 138:830-853
Estrogen-related receptor α (ERRα) is an orphan nuclear receptor that has been functionally implicated in the regulation of energy homeostasis. Herein is described the development of indazole-based N-alkylthiazolidenediones, which function in bioch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb5c376454ed13376d112e16a0c3b4e
https://doi.org/10.1016/j.ejmech.2017.07.015
https://doi.org/10.1016/j.ejmech.2017.07.015
Autor:
Monicah A. Otieno, Jose Silva, Eric Arnoult, Michael P. Winters, Hui Huang, Tonya Martin, Mark R. Player, Sanath K. Meegalla, Meghan Towers, Heng-Keang Lim, Jianying Liu, S. Paul Lee, Shuyuan Zhao, Alessandro Pocai, Fran Xu, Brian Rady
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(3)
GPR40 partial agonism is a promising new mechanism for the treatment of type 2 diabetes mellitus with clinical proof of concept. Most of the GPR40 agonists in the literature have a carboxylic acid functional group, which may pose a risk for idiosyncr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0564fc1d90c5555024fb8b23db310862
https://pubmed.ncbi.nlm.nih.gov/29258772
https://pubmed.ncbi.nlm.nih.gov/29258772
Autor:
J. D. Boot, L. De Garavilla, Deborah A. Polkovitch, A. Batheja, Zuzana Diamant, Meghan Towers, Michael R. D'Andrea, Stanley M. Belkowski, M. A. Mascelli, Brenda M. Hertzog
Publikováno v:
Clinical & Experimental Allergy. 39:1179-1186
Summary Background Secretory leucocyte protease inhibitor (SLPI), which is present in many physiological fluids including saliva, sputum and nasal discharge, is the most effective inhibitor of chymase. Previously, we demonstrated that chymase is able
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd256042e77f094b50d6067348a3707
https://doi.org/10.1111/j.1365-2222.2009.03247.x
https://doi.org/10.1111/j.1365-2222.2009.03247.x
Autor:
M. DeWitte, Y. Wang, M. T. Nakada, L. Yan, M. R. D'Andrea, Y. Hu, S. Ahrendt, P. Kesavan, Meghan Towers
Publikováno v:
Journal of Clinical Oncology. 25:4618-4618
4618 Background: CCL2 (MCP-1) is a chemoattractant protein highly expressed in a variety of cancer types. The expression level of CCL2 has been linked to aggressive disease progression, early dissemination, and poor survival in certain cancers. There
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45d8e372258bb3d312227750896a2b6f
https://doi.org/10.1200/jco.2007.25.18_suppl.4618
https://doi.org/10.1200/jco.2007.25.18_suppl.4618