Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Meghan S Blackledge"'
Autor:
Albert B Jeon, Andrés Obregón-Henao, David F Ackart, Brendan K Podell, Juan M Belardinelli, Mary Jackson, Tuan V Nguyen, Meghan S Blackledge, Roberta J Melander, Christian Melander, Benjamin K Johnson, Robert B Abramovitch, Randall J Basaraba
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180925 (2017)
There is an urgent need to develop new drug treatment strategies to control the global spread of drug-sensitive and multidrug-resistant Mycobacterium tuberculosis (M. tuberculosis). The ß-lactam class of antibiotics is among the safest and most wide
Externí odkaz:
https://doaj.org/article/13b71f62b38642b8ae75712bb88ac78d
Autor:
Chang Liu, Hua Zhang, Xian Peng, Meghan S. Blackledge, Robert E. Furlani, Haoting Li, Zhaoming Su, Roberta J. Melander, Christian Melander, Suzanne Michalek, Hui Wu
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Antibiotic tolerance within a biofilm community presents a serious public health challenge. Here, we report the identification of a 2-aminoimidazole derivative that inhibits biofilm formation by two pathogenic Gram-positive bacteria, Strepto
Externí odkaz:
https://doaj.org/article/343e3b9a42f041ec8cbd721edec050a8
Functionalized Self-Assembled Monolayers: Versatile Strategies to Combat Bacterial Biofilm Formation
Autor:
Pamela M. Lundin, Briana L. Fiser, Meghan S. Blackledge, Hannah L. Pickett, Abigail L. Copeland
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1613 (2022)
Bacterial infections due to biofilms account for up to 80% of bacterial infections in humans. With the increased use of antibiotic treatments, indwelling medical devices, disinfectants, and longer hospital stays, antibiotic resistant infections are s
Externí odkaz:
https://doaj.org/article/d0792ec2ce16459ca44cac25726b622b
Publikováno v:
ACS Chem Biol
Methicillin-resistant Staphylococcus aureus (MRSA) is a major threat to human health, as the US mortality rate outweighs those from HIV, tuberculosis, and viral hepatitis combined. In the wake of the COVID-19 pandemic, antibiotic-resistant bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5b9747a40d94b2f825adef7f94bb01
https://pubmed.ncbi.nlm.nih.gov/35467845
https://pubmed.ncbi.nlm.nih.gov/35467845
Autor:
Rachel Berndsen, Taylor Cunningham, Lauren Kaelin, Makayla Callender, W. Dexter Boldog, Brianna Viering, Ashley King, Najwa Labban, Julie A. Pollock, Heather B. Miller, Meghan S. Blackledge
Publikováno v:
ACS Medicinal Chemistry Letters. 13:483-491
Antibiotic-resistant infections are a pressing global concern, causing millions of deaths each year. Methicillin-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511ad9ac31b1b48a085b5d15be0cdebc
https://doi.org/10.1021/acsmedchemlett.1c00680
https://doi.org/10.1021/acsmedchemlett.1c00680
Autor:
Meghan S. Blackledge, Sergey M. Vinogradov, Allison S. Danell, Eric S. Anderson, Christian Melander, Eli G. Hvastkovs, Alex J. Robb
Publikováno v:
Electrochimica Acta. 268:276-282
A simple electrochemical assay to monitor the dispersion of Pseudomonas aeruginosa PA01 biofilm is described. Pyrolytic graphite (PG) electrodes were modified with P. aeruginosa PA01 using layer-by-layer (LbL) methods. The presence of the bacteria on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ef0a62673649b1ec4a058fb52e7fe84
https://doi.org/10.1016/j.electacta.2018.02.113
https://doi.org/10.1016/j.electacta.2018.02.113
Autor:
Kyra Gillard, Nicholas Cutrona, Rebecca Ulrich, Heather B. Miller, Mikaela Seemann, Meghan S. Blackledge
Publikováno v:
ACS infectious diseases. 5(8)
Staphylococcus epidermidis and Staphylococcus aureus are important human pathogens responsible for two-thirds of all postsurgical infections of indwelling medical devices. Staphylococci form robust biofilms that provide a reservoir for chronic infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c076766b090a64882d52079f8df985
https://pubmed.ncbi.nlm.nih.gov/31132246
https://pubmed.ncbi.nlm.nih.gov/31132246
Autor:
Alex J, Robb, Sergey, Vinogradov, Allison S, Danell, Eric, Anderson, Meghan S, Blackledge, Christian, Melander, Eli G, Hvastkovs
Publikováno v:
Electrochimica acta. 268
A simple electrochemical assay to monitor the dispersion of Pseudomonas aeruginosa PA01 biofilm is described. Pyrolytic graphite (PG) electrodes were modified with P. aeruginosa PA01 using layer-by-layer (LbL) methods. The presence of the bacteria on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8cc64aa01a0864995293c03ab401338
https://pubmed.ncbi.nlm.nih.gov/30504968
https://pubmed.ncbi.nlm.nih.gov/30504968
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d42852bf6bb3609635809cde1f90946b
https://doi.org/10.1096/fasebj.2020.34.s1.04408
https://doi.org/10.1096/fasebj.2020.34.s1.04408
Publikováno v:
Chemical biologydrug design. 92(5)
Methicillin-resistant Staphylococcus aureus (MRSA) is the leading cause of recurrent infections in humans including endocarditis, pneumonia, and toxic shock syndrome. Novel therapeutics to treat MRSA and other resistant bacteria are urgently needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bbf186078e20187a53e12b9ae3f4c6
https://pubmed.ncbi.nlm.nih.gov/29953721
https://pubmed.ncbi.nlm.nih.gov/29953721