Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Meghan L. Rudd"'
Autor:
Meghan L. Rudd, Nancy F. Hansen, Xiaolu Zhang, Mary Ellen Urick, Suiyuan Zhang, Maria J. Merino, National Institutes of Health Intramural Sequencing Center Comparative Sequencing Program, James C. Mullikin, Lawrence C. Brody, Daphne W. Bell
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Endometrioid endometrial carcinomas (EECs) are the most common histological subtype of uterine cancer. Late-stage disease is an adverse prognosticator for EEC. The purpose of this study was to analyze EEC exome mutation data to identify late-stage-sp
Externí odkaz:
https://doaj.org/article/aaed31c34d2b4dedb9f2db47d9827fa1
Autor:
Daphne W. Bell, Maria J. Merino, Dennis C. Sgroi, Andrew K. Godwin, Sarah Fogoros, Jessica C. Price, Meghan L. Rudd
Purpose: The goal of this study was to comprehensively define the incidence of mutations in all exons of PIK3CA in both endometrioid endometrial cancer (EEC) and nonendometrioid endometrial cancer (NEEC).Experimental Design: We resequenced all coding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb86422de90a876698fd56f987fd6912
https://doi.org/10.1158/1078-0432.c.6518952
https://doi.org/10.1158/1078-0432.c.6518952
Autor:
Daphne W. Bell, Maria J. Merino, Dennis C. Sgroi, Andrew K. Godwin, Sarah Fogoros, Jessica C. Price, Meghan L. Rudd
Supplementary Figure S1; Supplementary Tables S1-S5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d033f87c6e0ce26806974d8e71ec83
https://doi.org/10.1158/1078-0432.22442145.v1
https://doi.org/10.1158/1078-0432.22442145.v1
Supplementary Figure 1 from PIK3R1 (p85α) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3c1b487cfe8ce8fac83c5abdaf1eaa
https://doi.org/10.1158/0008-5472.22387845
https://doi.org/10.1158/0008-5472.22387845
Supplementary Figure 2 from PIK3R1 (p85α) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c60d0003a14684c03746ff12391ed95
https://doi.org/10.1158/0008-5472.22387842.v1
https://doi.org/10.1158/0008-5472.22387842.v1
Supplementary Methods and Tables 1-4 from PIK3R1 (p85α) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816182f0034f74f2087d44235d23e9f4
https://doi.org/10.1158/0008-5472.22387839.v1
https://doi.org/10.1158/0008-5472.22387839.v1
Autor:
Jessica C Price, Lana M Pollock, Meghan L Rudd, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, Matthieu Le Gallo, NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Praveen F Cherukuri, Nancy F Hansen, Kirk J McManus, Andrew K Godwin, Dennis C Sgroi, James C Mullikin, Maria J Merino, Philip Hieter, Daphne W Bell
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e63313 (2014)
Most endometrial cancers can be classified histologically as endometrioid, serous, or clear cell. Non-endometrioid endometrial cancers (NEECs; serous and clear cell) are the most clinically aggressive of the three major histotypes and are characteriz
Externí odkaz:
https://doaj.org/article/3e6912cd2b044f93a13ec39d39f4d8c9
Autor:
Daphne W. Bell, Nancy F. Hansen, Suiyuan Zhang, Mary Ellen Urick, Meghan L. Rudd, Jim C. Mullikin, Xiaoling Zhang, Brody Lc, Maria J. Merino
Endometrioid endometrial carcinomas (EECs) are the most common histological subtype of uterine cancer. Late-stage disease is an adverse prognosticator for EEC. The purpose of this study was to analyze EEC exome mutation data to identify late-stage-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::918d6c5df122bb8a0231bf22c9308df1
https://doi.org/10.1101/2021.04.26.21256125
https://doi.org/10.1101/2021.04.26.21256125
Autor:
Daphne W Bell, Nilabja Sikdar, Kyoo-Young Lee, Jessica C Price, Raghunath Chatterjee, Hee-Dong Park, Jennifer Fox, Masamichi Ishiai, Meghan L Rudd, Lana M Pollock, Sarah K Fogoros, Hassan Mohamed, Christin L Hanigan, NISC Comparative Sequencing Program, Suiyuan Zhang, Pedro Cruz, Gabriel Renaud, Nancy F Hansen, Praveen F Cherukuri, Bhavesh Borate, Kirk J McManus, Jan Stoepel, Payal Sipahimalani, Andrew K Godwin, Dennis C Sgroi, Maria J Merino, Gene Elliot, Abdel Elkahloun, Charles Vinson, Minoru Takata, James C Mullikin, Tyra G Wolfsberg, Philip Hieter, Dae-Sik Lim, Kyungjae Myung
Publikováno v:
PLoS Genetics, Vol 7, Iss 8, p e1002245 (2011)
ATAD5, the human ortholog of yeast Elg1, plays a role in PCNA deubiquitination. Since PCNA modification is important to regulate DNA damage bypass, ATAD5 may be important for suppression of genomic instability in mammals in vivo. To test this hypothe
Externí odkaz:
https://doaj.org/article/f77e2c0ad98744ec84cad927ff742253
Autor:
Matthieu Le Gallo, Nancy F. Hansen, Meghan L. Rudd, Daphne W. Bell, James C. Mullikin, Maria J. Merino, David G. Mutch, Mary Ellen Urick, Paul J. Goodfellow
Publikováno v:
Cancer. 124:65-73
BACKGROUND Uterine carcinosarcomas (UCSs) are a rare but clinically aggressive form of cancer. They are biphasic tumors consisting of both epithelial and sarcomatous components. The majority of uterine carcinosarcomas are clonal, with the carcinomato