Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Meghan L Bucher"'
Autor:
Irene Lee, Ava C. Knickerbocker, Charlotte R. Depew, Elizabeth L. Martin, Jocelyn Dicent, Gary W. Miller, Meghan L. Bucher
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
IntroductionThe nematode, Caenorhabditis elegans (C. elegans), is an advantageous model for studying developmental toxicology due to its well-defined developmental stages and homology to humans. It has been established that across species, dopaminerg
Externí odkaz:
https://doaj.org/article/d6a088b69e5e46f384e172266a0b87c3
Autor:
Catherine E.M. Aiken, Azita Amiri, Faith L. Anderson, Arthur Argenson, Anna Arita, Hrayr Attarian, Alison Berner, Vineet Bhandari, Vishwanath Bhat, Angelo Jose Goncalves Bos, Neil A. Bradbury, Meghan L. Bucher, Jan Burns, Ilaria Campesi, Arturo Casadevall, Hossein Chiti, Dorte M. Christiansen, Beth Coad, Dolores Corella, Ellie J. Coromilas, Romina Garcia de leon, Virginia Devi-Chou, Jocelyn Dicent, Mehmet Tevfik Dorak, Gillian Einstein, Harun Fajkovic, Ferric C. Fang, Liana Fattore, Anne Fausto-Sterling, Alireza Fazeli, Dov Feldberg, Roger B. Fillingim, Flavia Franconi, Karen H. Frith, Andreas M. Fritzen, Michika Fukui, Liisa A.M. Galea, Dan Gazit, Zulma Gazit, Donato Gemmati, Josephine Giblin, Marek Glezerman, Kasun Godakumara, Sydney Gram, Antonio Guillamon, Susanne B. Haga, Jessica A. Hennessey, Masakatsu Hihara, William V. Holt, Antonia Hufnagel, Hideki Iwaguro, Tannaz Jamialahmadi, Daphna Joel, Emil Jovanov, Natsuko Kakudo, Bente Kiens, Jin Kyung Kim, Sylvia Kirchengast, Stephanie M. Kochav, Suranga P. Kodithuwakku, L.M. Kok, Peter Koopman, Zoe Krut, Atsuyuki Kuro, Ryosuke Kuroda, Satoshi Kushida, Yunjia Lai, Bonnie H. Lee, Ana Lleo, Anne-Marie Lundsgaard, Adriana C. Maggi, Satoshi Matsushita, Margaret M. McCarthy, Alice Melloni, Maurizio Meloni, Gary W. Miller, Suresh Mishra, Toshihito Mitsui, Hiroshi Mizuno, R.G.H.H. Nelissen, Petr Nickl, Tatsuya Nomura, Sabine Oertelt-Prigione, Gabriela Guimaraes Oliveira-Zumda, Jose M. Ordovas, Negin Parsamanesh, Gadi Pelled, Andrei A. Puiu, M. Natasha Rajah, Doodipala Samba Reddy, Željko Reiner, Amirhossein Sahebkar, Yoshitomo Saita, Ibis Sánchez-Serrano, Reza Sari Motlagh, Ivanka Savic, Manuela Schmidinger, Caleb M. Schmidt, Michael A. Schmidt, Radislav Sedlacek, Angelo Serani, Fidaa Shaib, Shahrokh F. Shariat, Keshav K. Singh, Satoshi Sobajima, Dustin J. Sokolowski, Marla B. Sokolowski, Simón(e) D. Sun, Zhongxin Sun, Jihyun Sung, Linn Amanda Syding, Veena Taneja, Diethard Tautz, Lisa M. Thurston, Siobhan Tierney, Veronica Tisato, Morikuni Tobita, Jessica Tollkuhn, Masanori Tsubosaka, Valter Tucci, Carme Uribe, A. Van Noort, Mikhail Votinov, Reubs J. Walsh, Elaine Y. Wan, Leire Zubiaurre-Elorza
Publikováno v:
Principles of Gender-Specific Medicine ISBN: 9780323885348
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecb3833742d2c6524e411d2266f8fcf0
https://doi.org/10.1016/b978-0-323-88534-8.09993-4
https://doi.org/10.1016/b978-0-323-88534-8.09993-4
Publikováno v:
Principles of Gender-Specific Medicine ISBN: 9780323885348
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a1e47d36efe451397ff98127eb96f3
https://doi.org/10.1016/b978-0-323-88534-8.00035-3
https://doi.org/10.1016/b978-0-323-88534-8.00035-3
Publikováno v:
Exposome. 3
The health and disease of an individual is mediated by their genetics, a lifetime of environmental exposures, and interactions between the two. Genetic or biological sex, including chromosome composition and hormone expression, may influence both the
Autor:
Vrinda Kalia, Megan M Niedzwiecki, Joshua M Bradner, Fion K Lau, Faith L Anderson, Meghan L Bucher, Katherine E Manz, Alexa Puri Schlotter, Zoe Coates Fuentes, Kurt D Pennell, Martin Picard, Douglas I Walker, William T Hu, Dean P Jones, Gary W Miller
Publikováno v:
PNAS Nexus. 1
Exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) has been associated with increased risk of Alzheimer's disease (AD), a disease also associated with hyperphosphorylated tau (p-tau) protein aggregation. We investigated whether exposure
Autor:
Douglas I. Walker, Hu Wt, Kalia, Coates Fuentes Z, Joshua M. Bradner, Fion K Lau, Martin Picard, Katherine E. Manz, Meghan L Bucher, Megan M. Niedzwiecki, Dean P. Jones, Gary W. Miller, Kurt D. Pennell
BackgroundThe formation of hyperphosphorylated tau (p-tau) protein tangles in neurons is a pathological marker of Alzheimer’s disease (AD). Exposure to the pesticide dichlorodiphenyltrichloroethane (DDT) has been associated with increased risk of A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eebb2a623cfed38ce91e40d866c6f90f
https://doi.org/10.1101/2021.06.14.448355
https://doi.org/10.1101/2021.06.14.448355
Autor:
Merry Chen, Monica Sharma, Fion K Lau, Dean P. Jones, Gary W. Miller, Michelle A. Johnson, Douglas I. Walker, Vrinda Kalia, Meghan L Bucher, Joshua M. Bradner
Publikováno v:
Toxicol Sci
The proper storage and release of monoamines contributes to a wide range of neuronal activity. Here, we examine the effects of altered vesicular monoamine transport in the nematode Caenorhabditis elegans. The gene cat-1 is responsible for the encodin
Autor:
Carlie A. Black, Gary W. Miller, Kenny Igarza, Meghan L Bucher, Lauren Jonas, Joshua M. Bradner
Publikováno v:
Chem Res Toxicol
Impairments in the vesicular packaging of dopamine result in an accumulation of dopamine in the cytosol. Cytosolic dopamine is vulnerable to two metabolic processes - enzymatic catabolism and enzymatic- or auto-oxidation - that form toxic metabolites
Autor:
Meghan L Bucher, Michelle A. Johnson, Douglas I. Walker, Vrinda Kalia, Merry Chen, Monica Sharma, Gary W. Miller, Fion K Lau, Joshua M. Bradner, Dean P. Jones
The proper storage and release of monoamines contributes to a wide range of neuronal activity. Here, we examine the effects of altered vesicular monoamine transport in the nematodeC. elegans. The genecat-1is responsible for the encoding of the vesicu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::840ae1cde10795d67d3e1a8dc4b90c3a
https://doi.org/10.1101/2020.10.02.324095
https://doi.org/10.1101/2020.10.02.324095
Autor:
Amanda D. Mortimer, Teresa G. Hastings, Caitlyn W. Barrett, Edward A. Burton, Meghan L. Bucher, J. Timothy Greenamyre, Connor J. Moon
Publikováno v:
npj Parkinson's Disease, Vol 6, Iss 1, Pp 1-13 (2020)
NPJ Parkinson's Disease
NPJ Parkinson's Disease
The catecholamine neurotransmitter dopamine has the potential to act as an endogenous neurotoxin when its vesicular sequestration is dysregulated. Despite postmortem analyses from patients with Parkinson’s disease that demonstrate decreased vesicul