Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Meghan L, Verschoor"'
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13565 (2010)
Cancer cells predominantly utilize glycolysis for ATP production even in the presence of abundant oxygen, an environment that would normally result in energy production through oxidative phosphorylation. Although the molecular mechanism for this meta
Externí odkaz:
https://doaj.org/article/bfbfca80416a4450b4722cbcd769706e
Autor:
Andrew Harbottle, Ryan Parr, Gurmit Singh, Robert G. Ungard, Meghan L. Verschoor, John P. Jakupciak
Publikováno v:
BioMed Research International, Vol 2013 (2013)
BioMed Research International
BioMed Research International
The area of mitochondrial genomics has undergone unprecedented growth over the past several years. With the advent of the age of omics, investigations have reached beyond the nucleus to encompass the close biological communication and finely coordina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395b3f405afaa69a0e0ba98254ed8c1e
https://doi.org/10.1155/2013/612369
https://doi.org/10.1155/2013/612369
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 88:204-219
The mitochondria are unique cellular organelles that contain their own genome and, in conjunction with the nucleus, are able to transcribe and translate genes encoding components of the electron transport chain (ETC). To do so, the mitochondria must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a572cd8657ba5f494d9c1d7cf4f318c4
https://doi.org/10.1139/y09-135
https://doi.org/10.1139/y09-135
Publikováno v:
Future oncology (London, England). 11(4)
ABSTRACT Despite huge economic and intellectual investments, developing effective cancer treatments continues to be an overarching challenge. Engineered oncolytic viruses (OVs) present self-amplifying immunotherapy platforms capable of preferential c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db00e64c70b6947d602ac4d1ff2df00
https://pubmed.ncbi.nlm.nih.gov/25686121
https://pubmed.ncbi.nlm.nih.gov/25686121
Publikováno v:
Molecular Therapy: Oncolytics, Vol 2, Iss, Pp-(2015)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Oncolytic viruses selectively replicate in cancer cells by exploiting biochemical differences between normal and tumor cells. Treatment with epigenetic modifiers such as 5-Azacytidine, a DNA methyltransferase inhibitor, increases the replication and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2565caf2a66d0bd9fd321b56dd322765
Oncolytic viruses are a novel anticancer therapy with the ability to target tumor cells, while leaving healthy cells intact. For this strategy to be successful, recent studies have shown that involvement of the host immune system is essential. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6121d09b9aa53e8ea8c2b292a6f27b36
https://europepmc.org/articles/PMC4354327/
https://europepmc.org/articles/PMC4354327/
Publikováno v:
Cancer & Metabolism
Background The Ets-1 proto-oncogene is frequently upregulated in cancer cells, with known involvement in cancer angiogenesis, metastasis, and more recently energy metabolism. In this study we have performed various bioinformatic analyses on existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b05d565b82a1fb2da20ce8d5a989f16
https://pubmed.ncbi.nlm.nih.gov/24280356
https://pubmed.ncbi.nlm.nih.gov/24280356
Publikováno v:
Canadian journal of physiology and pharmacology. 88(3)
The mitochondria are unique cellular organelles that contain their own genome and, in conjunction with the nucleus, are able to transcribe and translate genes encoding components of the electron transport chain (ETC). To do so, the mitochondria must
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9c711addc464418400915a184b72f80
https://pubmed.ncbi.nlm.nih.gov/20393586
https://pubmed.ncbi.nlm.nih.gov/20393586
Publikováno v:
Cancer Research. 70:43-43
Cancer cells predominantly utilize glycolysis for ATP production even in the presence of abundant oxygen, an environment that would normally result in energy production through oxidative phosphorylation. Although the molecular mechanism for this meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d1ad5a607a02fc04c28148df4ecc75e
https://doi.org/10.1158/1538-7445.am10-43
https://doi.org/10.1158/1538-7445.am10-43
Autor:
Meghan L. Verschoor, Gurmit Singh
Publikováno v:
Molecular Cancer
Background Ovarian cancer is characterized by high rates of metastasis and therapeutic resistance. Many chemotherapeutic agents rely on the induction of oxidative stress to cause cancer cell death, thus targeting redox regulation is a promising strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9009cd33bdb1a95c57ece1ab2f2621