Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Meghan, Beman"'
Autor:
Eva Cataldo, Kathryn E. Reinicke, Dmitry Klokov, Meghan Beman, Konstantin Leskov, Lindsey D. Mayo, David A. Boothman, S Israel, Tracy L. Criswell, L Sampalth, Shinako Araki
Publikováno v:
The British Journal of Radiology. :106-113
Severe trauma (e.g. whole body ionising radiation (IR)), leads to multiple organ dysfunction (MOD) and death. Although not completely understood, proposed triggering events of MOD include reactive oxygen species (ROS), released Ca2+ from endoplasmic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b411d0622432f51db2b1ab2b056c72e
https://doi.org/10.1259/bjr/18105113
https://doi.org/10.1259/bjr/18105113
Autor:
Meghan Beman, Shinako Araki, Lakshmi Sampath, David L. Wilson, David A. Boothman, Kristin Frinkley, Tracy Criswell, Dmitry Klokov, Konstantin Leskov
Publikováno v:
International Congress Series. 1258:219-232
Secretory clusterin (sCLU), a multifunctional glycoprotein, is induced in response to ionizing radiation (IR) at low and high doses. We are, therefore, developing a cellular biodosimetry system utilizing the CLU promoter-luciferase-neo® genetic cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::730cd499aa29876872cfd5b5cb12a253
https://doi.org/10.1016/s0531-5131(03)01154-3
https://doi.org/10.1016/s0531-5131(03)01154-3
Publikováno v:
Europe PubMed Central
The clusterin (CLU) protein has been reported to have both cytoprotective and cytotoxic activities. Previous data from our lab suggest that the secretory form of CLU (sCLU) is cytoprotective and induced after very low, nontoxic doses of ionizing radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ded97cdbc76fdbec29ba765fe712af
https://doi.org/10.4161/cbt.2.4.430
https://doi.org/10.4161/cbt.2.4.430
Autor:
Jinming Gao, David A. Boothman, Meghan Beman, Andrew J Bruening, Andy F. Wiedmann, Norased Nasongkla, Dale Ray, William Bornmann
Publikováno v:
Pharmaceutical Research. 20:1626-1633
Purpose. To explore the use of cyclodextrins (CD) to form inclusion complexes with β-lapachone (β-lap) to overcome solubility and bioavailability problems previously noted with this drug.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fde9a6e96f3b5b93e4c62aaea08bf22
https://doi.org/10.1023/a:1026143519395
https://doi.org/10.1023/a:1026143519395
Autor:
Shinako Araki, Eva Cataldo, David A. Boothman, Konstantin Leskov, Lindsey D. Mayo, Meghan Beman, Tracy Criswell
Publikováno v:
The Journal of biological chemistry. 280(14)
Secretory clusterin protein (sCLU) is a general genotoxic stress-induced, pro-survival gene product implicated in aging, obesity, heart disease, and cancer. However, the regulatory signal transduction processes that control sCLU expression remain und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb92f75fb1bed85324f12fd3dc17fccb
https://pubmed.ncbi.nlm.nih.gov/15689620
https://pubmed.ncbi.nlm.nih.gov/15689620
Autor:
Norased, Nasongkla, Andy F, Wiedmann, Andrew, Bruening, Meghan, Beman, Dale, Ray, William G, Bornmann, David A, Boothman, Jinming, Gao
Publikováno v:
Pharmaceutical research. 20(10)
To explore the use of cyclodextrins (CD) to form inclusion complexes with beta-lapachone (beta-lap) to overcome solubility and bioavailability problems previously noted with this drug.Inclusion complexes between beta-lap and four cyclodextrins (alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c73ebe591fa21e473b24496e82bb6105
https://pubmed.ncbi.nlm.nih.gov/14620518
https://pubmed.ncbi.nlm.nih.gov/14620518