Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Meghan, Beman"'
Autor:
Eva Cataldo, Kathryn E. Reinicke, Dmitry Klokov, Meghan Beman, Konstantin Leskov, Lindsey D. Mayo, David A. Boothman, S Israel, Tracy L. Criswell, L Sampalth, Shinako Araki
Publikováno v:
The British Journal of Radiology. :106-113
Severe trauma (e.g. whole body ionising radiation (IR)), leads to multiple organ dysfunction (MOD) and death. Although not completely understood, proposed triggering events of MOD include reactive oxygen species (ROS), released Ca2+ from endoplasmic
Autor:
Meghan Beman, Shinako Araki, Lakshmi Sampath, David L. Wilson, David A. Boothman, Kristin Frinkley, Tracy Criswell, Dmitry Klokov, Konstantin Leskov
Publikováno v:
International Congress Series. 1258:219-232
Secretory clusterin (sCLU), a multifunctional glycoprotein, is induced in response to ionizing radiation (IR) at low and high doses. We are, therefore, developing a cellular biodosimetry system utilizing the CLU promoter-luciferase-neo® genetic cons
Publikováno v:
Europe PubMed Central
The clusterin (CLU) protein has been reported to have both cytoprotective and cytotoxic activities. Previous data from our lab suggest that the secretory form of CLU (sCLU) is cytoprotective and induced after very low, nontoxic doses of ionizing radi
Autor:
Jinming Gao, David A. Boothman, Meghan Beman, Andrew J Bruening, Andy F. Wiedmann, Norased Nasongkla, Dale Ray, William Bornmann
Publikováno v:
Pharmaceutical Research. 20:1626-1633
Purpose. To explore the use of cyclodextrins (CD) to form inclusion complexes with β-lapachone (β-lap) to overcome solubility and bioavailability problems previously noted with this drug.
Autor:
Shinako Araki, Eva Cataldo, David A. Boothman, Konstantin Leskov, Lindsey D. Mayo, Meghan Beman, Tracy Criswell
Publikováno v:
The Journal of biological chemistry. 280(14)
Secretory clusterin protein (sCLU) is a general genotoxic stress-induced, pro-survival gene product implicated in aging, obesity, heart disease, and cancer. However, the regulatory signal transduction processes that control sCLU expression remain und
Autor:
Norased, Nasongkla, Andy F, Wiedmann, Andrew, Bruening, Meghan, Beman, Dale, Ray, William G, Bornmann, David A, Boothman, Jinming, Gao
Publikováno v:
Pharmaceutical research. 20(10)
To explore the use of cyclodextrins (CD) to form inclusion complexes with beta-lapachone (beta-lap) to overcome solubility and bioavailability problems previously noted with this drug.Inclusion complexes between beta-lap and four cyclodextrins (alpha
Autor:
Murphy, Maureen
Publikováno v:
Cancer Biology and Therapy; July 2003, Vol. 2 Issue: 4 p381-382, 2p
Autor:
Maureen E. Murphy
Publikováno v:
Cancer biologytherapy. 2(4)
Commentary to:Repression of IR-Inducible Clusterin Expression by the p53 Tumor Suppressor ProteinTracy Criswell, Dmitry Klokov, Meghan Beman, JP Lavik and David A. Boothman