Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Meggie Kuypers"'
Autor:
Qiaochu Lin, Meggie Kuypers, Zhewei Liu, Julia K Copeland, Donny Chan, Susan J Robertson, Jean Kontogiannis, David S Guttman, E. Kate Banks, Dana J Philpott, Thierry Mallevaey
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Invariant Natural Killer T (iNKT) cells are unconventional T cells that respond to glycolipid antigens found in microbes in a CD1d-dependent manner. iNKT cells exert innate-like functions and produce copious amounts of cytokines, chemokines and cytot
Externí odkaz:
https://doaj.org/article/545f76b4b1774dba9ea0db17924006eb
Autor:
Pailin Chiaranunt, Kyle Burrows, Louis Ngai, Eric Y Cao, Siu Ling Tai, Helen Liang, Homaira Hamidzada, Anthony Wong, Meggie Kuypers, Tijana Despot, Abdul Momen, Sung Min Lim, Thierry Malleavey, Tyrrell Conway, Hiromi Imamura, Slava Epelman, Arthur Mortha
SummaryMaintaining intestinal macrophage (MP) heterogeneity is critical to ensure tissue homeostasis and host defense. The gut microbiota and host factors are thought to synergistically shape colonic MP development, although there remains a fundament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52df4858e4874c8e76b113ab0d27a22c
https://doi.org/10.1101/2022.03.23.485563
https://doi.org/10.1101/2022.03.23.485563
Autor:
Qiaochu Lin, Juan Mauricio Umaña, Mayra Cruz Tleugabulova, Thierry Mallevaey, Clarissa Wirianto, Irene Lau, Meng Zhao, Mitchell Kronenberg, Meggie Kuypers
Publikováno v:
The Journal of Immunology. 202:2276-2286
Invariant NKT (iNKT) cells are innate lipid-reactive T cells that develop and differentiate in the thymus into iNKT1/2/17 subsets, akin to TH1/2/17 conventional CD4 T cell subsets. The factors driving the central priming of iNKT cells remain obscure,
Autor:
Qiaochu Lin, Carolina de Amat Herbozo, Meggie Kuypers, Thierry Mallevaey, Christophe Paget, Irene Lau
Publikováno v:
ImmunoHorizons
ImmunoHorizons, The American Association of Immunologists, Inc, 2020, 4 (12), pp.797-808. ⟨10.4049/immunohorizons.2000100⟩
ImmunoHorizons, The American Association of Immunologists, Inc, 2020, 4 (12), pp.797-808. ⟨10.4049/immunohorizons.2000100⟩
CD1d-restricted invariant NKT (iNKT) cells are innate-like T cells that respond to glycolipids, a class of Ags that are invisible to conventional T cells. iNKT cells develop in the thymus where they receive strong “agonist” TCR signals. During th
Publikováno v:
Mucosal immunology. 13(6)
The mammalian immune system is equipped with unconventional T cells that respond to microbial molecules such as glycolipids and small-molecule metabolites, which are invisible to conventional CD4 and CD8 T cells. Unconventional T cells include invari
Publikováno v:
Microbes and Infection. 23:104817
The microbiota is a driving force that influences host physiological functions. In this review, we discuss some of the methods that have been used in the pursuit of relevant host-microbiota interactions that control immune fitness and disease suscept