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pro vyhledávání: '"Megen C Wittling"'
Autor:
Gregory B Lesinski, Chrystal M Paulos, Hannah M Knochelmann, Megan M Wyatt, Guillermo O Rangel Rivera, Anna C Cole, Megen C Wittling
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background How distinct methods of host preconditioning impact the efficacy of adoptively transferred antitumor T helper cells is unknown.Methods CD4+ T cells with a transgenic T-cell receptor that recognize tyrosinase-related peptide (TRP)-1 melanom
Externí odkaz:
https://doaj.org/article/fe2e22541bba40599235ed797c618c73
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Type I interferons (IFN-I) were first discovered as an antiviral factor by Isaacs and Lindenmann in 1957, but they are now known to also modulate innate and adaptive immunity and suppress proliferation of cancer cells. While much has been revealed ab
Externí odkaz:
https://doaj.org/article/b34d915d08b74a1ea4bf848812a3bb83
Autor:
Megen C. Wittling, Anna C. Cole, Brianna Brammer, Kailey G. Diatikar, Nicole C. Schmitt, Chrystal M. Paulos
Publikováno v:
Cancers, Vol 16, Iss 16, p 2858 (2024)
CAR T cells require optimization to be effective in patients with solid tumors. There are many barriers affecting their ability to succeed. One barrier is persistence, as to achieve an optimal antitumor response, infused CAR T cells must engraft and
Externí odkaz:
https://doaj.org/article/6ec909e339984211a2385196601617df