Piper sarmentosum inhibits ICAM-1 and Nox4 gene expression in oxidative stress-induced human umbilical vein endothelial cells

Autor: Megat Mohd Nordin Nor, Hui Chua, Zakaria Zaiton, Ugusman Azizah

Publikováno v: BMC Complementary and Alternative Medicine, Vol 11, Iss 1, p 31 (2011)

Abstract Background Aqueous extract of Piper sarmentosum (AEPS) is known to possess antioxidant and anti-atherosclerotic activities but the mechanism responsible for it remains unclear. In early part of atherosclerosis, nuclear factor-kappa B (NF-κB

Externí odkaz: https://doaj.org/article/6f1cc4e98b7f4f0cbb645ce7d509c8cf

Piper sarmentosum as an antioxidant on oxidative stress in human umbilical vein endothelial cells induced by hydrogen peroxide

Autor: Megat Mohd Nordin Nor Anita, Abdullah Mahdy Zaleha, Abdul Hamid Hafizah, Zakaria Zaiton, Amom Zulkhairi, Adenan Mohd Ilham

Publikováno v: Journal of Zhejiang University. Science. B. 11(5)

Endothelial cell death due to increased reactive oxygen species (ROS) may contribute to the initial endothelial injury, which promotes atherosclerotic lesion formation. Piper sarmentosum (PS), a natural product, has been shown to have an antioxidant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae84e191daf79206893b009ab73a9ac
https://pubmed.ncbi.nlm.nih.gov/20443214

The use of Piper sarmentosum leaves aqueous extract (Kadukmy™) as antihypertensive agent in spontaneous hypertensive rats.

Autor: Mohd Zainudin M; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia. drmeihwa@yahoo.com.; Department of Basic Medical Sciences (Physiology), Kulliyyah of Medicine, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, 25200, Kuantan, Pahang, Malaysia. drmeihwa@yahoo.com., Zakaria Z; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia. zaitonukm@gmail.com., Megat Mohd Nordin NA; Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia. noranitamn@gmail.com.

Publikováno v: BMC complementary and alternative medicine [BMC Complement Altern Med] 2015 Mar 10; Vol. 15, pp. 54. Date of Electronic Publication: 2015 Mar 10.