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pro vyhledávání: '"Megan Vitko"'
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175467 (2017)
Growth deficits are common in cystic fibrosis (CF), but their cause is complex, with contributions from exocrine pancreatic insufficiency, pulmonary complications, gastrointestinal obstructions, and endocrine abnormalities. The CF mouse model display
Externí odkaz:
https://doaj.org/article/0b8d49213deb4992a257ad80fb5110c0
Autor:
Edvar Onsoyen, A.H. Myrset, Philip D. Rye, Mitchell L. Drumm, Craig A. Hodges, Megan Vitko, Arne Dessen, Dana M. Valerio
Publikováno v:
Journal of Cystic Fibrosis. 15:745-751
Background Cystic fibrosis (CF) patients experience intestinal complications characterized by the accumulation of thick viscous mucus. CF mice were utilized to determine if a novel guluronate oligomer, OligoG, may be a potential therapy in reducing i
Autor:
Dana M. Valerio, Walter F. Boron, Thomas J. Kelley, Craig A. Hodges, Daniel R. McHugh, Mitchell L. Drumm, Shuyu Hao, Robert C. Stern, Anjum Jafri, Kimberly McBennett, Calvin U. Cotton, Megan Vitko, Fraser J. Moss
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Gastrointestinal dysfunction in cystic fibrosis (CF) is a prominent source of pain among patients with CF. Linaclotide, a guanylate cyclase C (GCC) receptor agonist, is a US Food and Drug Administration-approved drug prescribed for chronic constipati
Autor:
Kai Jiang, Rebecca J. Darrah, Xin Yu, Christopher A Flask, Sen Jiao, Megan Vitko, Craig A. Hodges
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 15(1)
Background Altered cardiac function has been observed in cystic fibrosis transmembrane regulator (CFTR) knockout mice. However, whether this alteration is a direct effect of CFTR disruption in the heart, or is secondary due to systemic loss of CFTR,
Autor:
Mitchell L. Drumm, Rebecca J. Darrah, Megan Vitko, Ilya Bederman, Craig A. Hodges, Dana M. Valerio
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0175467 (2017)
PLoS ONE, Vol 12, Iss 4, p e0175467 (2017)
Growth deficits are common in cystic fibrosis (CF), but their cause is complex, with contributions from exocrine pancreatic insufficiency, pulmonary complications, gastrointestinal obstructions, and endocrine abnormalities. The CF mouse model display