Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Megan Varnum"'
Autor:
Kendell M. Pawelec, Megan Varnum, Jack R. Harkema, Bruce Auerbach, Scott D. Larsen, Richard R. Neubig
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 6, Pp n/a-n/a (2022)
Abstract Bleomycin‐induced lung fibrosis is a debilitating disease, linked to high morbidity and mortality in chemotherapy patients. The MRTF/SRF transcription pathway has been proposed as a potential therapeutic target, as it is critical for myofi
Externí odkaz:
https://doaj.org/article/44200ee4fb6143fda9eddfcf3ba10f31
Autor:
Scott D. Larsen, Megan Varnum, Jack R. Harkema, Kendell M. Pawelec, Bruce Auerbach, Richard R. Neubig
Drug-induced lung fibrosis is a debilitating disease, linked to high morbidity and mortality. A number of drugs can cause fibrosis, many of which are used to treat cancer, including chemotherapy agents and immune checkpoint inhibitors. The MRTF/SRF t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faf8feb7989866fcf492ff1307ea244d
https://doi.org/10.1101/2021.09.09.459118
https://doi.org/10.1101/2021.09.09.459118
Publikováno v:
Neurobiology of Aging. 50:134-143
The precise molecular and cellular events responsible for age-dependent cognitive dysfunctions remain unclear. We report that Rheb (ras homolog enriched in brain) GTPase, an activator of mammalian target of rapamycin (mTOR), regulates memory function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de44f7f127b3d92745f6985d70f3ea07
https://doi.org/10.1016/j.neurobiolaging.2016.11.006
https://doi.org/10.1016/j.neurobiolaging.2016.11.006