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pro vyhledávání: '"Megan T Zhao"'
Autor:
John DiGiovanni, Weiwei Fu, Qi Yin, Sungyong You, Lucy M. Driver, Amelia U Schirmer, David H. Drewry, Stephen J. Freedland, Everardo Macias, Megan T Zhao
Publikováno v:
Molecular carcinogenesisREFERENCES. 61(3)
Current advancements in prostate cancer (PC) therapies have been successful in slowing PC progression and increasing life expectancy; however, there is still no curative treatment for advanced metastatic castration resistant PC (mCRPC). Most treatmen
Autor:
Amelia U Schirmer, David H. Drewry, John DiGiovanni, Carrow I. Wells, Megan T Zhao, Lauren E. Howard, Julie E. Pickett, Xuan Yang, Gayathri R. Devi, Sungyong You, Jen-Tsan Chi, Everardo Macias, Sean N. O’Bryne, Stephen F Freedland, Lucy M. Driver, Benjamin J. Eduful
Publikováno v:
Mol Ther
Serine/threonine kinase 3 (STK3) is an essential member of the highly conserved Hippo Tumor suppressor pathway which regulates Yes 1 Associated protein (YAP1) and TAZ. STK3 and its paralog STK4 initiate a phosphorylation cascade that regulate YAP1/TA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7a89ba374a4b6a24a1755ee160a896
https://doi.org/10.1101/2021.02.21.432137
https://doi.org/10.1101/2021.02.21.432137
Autor:
Amelia U. Schirmer, Lucy M. Driver, Megan T. Zhao, Carrow I. Wells, Xuan Yang, David H. Drewry, Ivan Spasojevic, Everardo Macias
Publikováno v:
Molecular Cancer Therapeutics. 20:P149-P149
Prostate cancer (PC) is the second cause of cancer related deaths in men. Most therapies target the Androgen Receptor (AR) which can prolong survival, but resistance emerges and patients eventually succumb to the disease. This highlights the need for