Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Megan T Baldridge"'
Autor:
Somya Aggarwal, Forrest C Walker, James S Weagley, Broc T McCune, Xiaofen Wu, Lawrence A Schriefer, Heyde Makimaa, Dylan Lawrence, Pratyush Sridhar, Megan T Baldridge
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011961 (2024)
Noroviruses (NoVs) are a leading cause of viral gastroenteritis. Despite global clinical relevance, our understanding of how host factors, such as antiviral cytokines interferons (IFNs), modulate NoV population dynamics is limited. Murine NoV (MNoV)
Externí odkaz:
https://doaj.org/article/156a71645a0f4958af0295641a001002
Autor:
Jacob A Van Winkle, Stefan T Peterson, Elizabeth A Kennedy, Michael J Wheadon, Harshad Ingle, Chandni Desai, Rachel Rodgers, David A Constant, Austin P Wright, Lena Li, Maxim N Artyomov, Sanghyun Lee, Megan T Baldridge, Timothy J Nice
Publikováno v:
eLife, Vol 11 (2022)
Interferon-lambda (IFN-λ) protects intestinal epithelial cells (IECs) from enteric viruses by inducing expression of antiviral IFN-stimulated genes (ISGs). Here, we find that bacterial microbiota stimulate a homeostatic ISG signature in the intestin
Externí odkaz:
https://doaj.org/article/49f905267f26475caccf534d5cf8c0dd
Autor:
Forrest C Walker, Ebrahim Hassan, Stefan T Peterson, Rachel Rodgers, Lawrence A Schriefer, Cassandra E Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dylan Lawrence, Broc T McCune, Vincent R Graziano, Larissa Lushniak, Sanghyun Lee, Alexa N Roth, Stephanie M Karst, Timothy J Nice, Jonathan J Miner, Craig B Wilen, Megan T Baldridge
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009402 (2021)
Interferons (IFNs) are key controllers of viral replication, with intact IFN responses suppressing virus growth and spread. Using the murine norovirus (MNoV) system, we show that IFNs exert selective pressure to limit the pathogenic evolutionary pote
Externí odkaz:
https://doaj.org/article/90fb07bf8a2e40fb883cfc49c1867b66
Autor:
Daniel Schnepf, Pedro Hernandez, Tanel Mahlakõiv, Stefania Crotta, Meagan E Sullender, Stefan T Peterson, Annette Ohnemus, Camille Michiels, Ian Gentle, Laure Dumoutier, Celso A Reis, Andreas Diefenbach, Andreas Wack, Megan T Baldridge, Peter Staeheli
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0247738 (2021)
The commensal microbiota regulates susceptibility to enteric pathogens by fine-tuning mucosal innate immune responses, but how susceptibility to enteric viruses is shaped by the microbiota remains incompletely understood. Past reports have indicated
Externí odkaz:
https://doaj.org/article/d68b02450db24632b3ba2774fe30dfac
Autor:
Vincent R Graziano, Forrest C Walker, Elizabeth A Kennedy, Jin Wei, Khalil Ettayebi, Madison S Strine, Renata B Filler, Ebrahim Hassan, Leon L Hsieh, Arthur S Kim, Abimbola O Kolawole, Christiane E Wobus, Lisa C Lindesmith, Ralph S Baric, Mary K Estes, Robert C Orchard, Megan T Baldridge, Craig B Wilen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008242 (2020)
Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major determinant of cell tropism, host range, and pathogenesis. The bona fide receptor for HNoV is unkn
Externí odkaz:
https://doaj.org/article/c2674dd032554c20845ee5f10d202eda
Autor:
Meagan E Sullender, Megan T Baldridge
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007183 (2018)
Externí odkaz:
https://doaj.org/article/101c0f892bc7426fa158eb6b671e2625
Autor:
Marta Celorrio, Kirill Shumilov, Rachel Rodgers, Lawrence Schriefer, Yuhao Li, Megan T. Baldridge, Stuart H. Friess
Publikováno v:
Journal of Neurotrauma. 40:772-787
Autor:
Yuhao Li, Megan T. Baldridge
Publikováno v:
Nature Microbiology. 8:363-366
Publikováno v:
Trends in microbiology. 30(8):778-792
The interferon (IFN) response is the major early innate immune response against invading viral pathogens and is even capable of mediating sterilizing antiviral immunity without the support of the adaptive immune system. Cumulative evidence suggests t
Autor:
Lisa Funkhouser-Jones, Rui Xu, Georgia Wilke, Yong Fu, Lawrence A Shriefer, Heyde Makimaa, Rachel Rodgers, Elizabeth A Kennedy, Kelli VanDussen, Thaddeus Stappenbeck, Megan T Baldridge, L. David Sibley
Publikováno v:
bioRxiv
Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children in resource-poor settings. Susceptibility rapidly declines with age, associated with changes in the microbiota. To explore microbial influences on susceptibility, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1733a643d6991dd27acd6ae5c2997e
https://doi.org/10.1101/2023.05.25.542157
https://doi.org/10.1101/2023.05.25.542157