Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Megan Sutcliffe"'
Autor:
Ben Mulhearn, Lysette Marshall, Megan Sutcliffe, Susan K. Hannes, Chamith Fonseka, Tracy Hussell, Soumya Raychaudhuri, Anne Barton, Sebastien Viatte
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundDespite the report of an imbalance between CD4+ T helper (Th) cell subsets in rheumatoid arthritis (RA), patient stratification for precision medicine has been hindered by the discovery of ever more Th cell subsets, as well as contradictory
Externí odkaz:
https://doaj.org/article/90edaa19b76c4d2bbf507c9f97876dc6
Autor:
Ben Mulhearn, Lysette Marshall, Megan Sutcliffe, Anne Barton, Soumya Raychaudhuri, Sebastien Viatte
Publikováno v:
Rheumatology. 61
Background/Aims Treating rheumatoid arthritis (RA) continues to rely heavily on a trial-and-error approach. The potential of deep immunophenotyping of peripheral blood remains to be proven in tailoring treatment to an individual’s biological variab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::596c312fcdbf27d95a52d4b8052b2bd0
https://doi.org/10.1093/rheumatology/keac133.189
https://doi.org/10.1093/rheumatology/keac133.189
Autor:
Megan Sutcliffe, Nisha Nair, James Oliver, Ann W Morgan, John D Isaacs, Anthony G Wilson, Suzanne M M Verstappen, Sebastien Viatte, Kimme L Hyrich, Andrew P Morris, Anne Barton, Darren Plant
Publikováno v:
Sutcliffe, M, Nair, N, Oliver, J, Morgan, A W, Isaacs, J D, Wilson, A, Verstappen, S, Viatte, S, Hyrich, K, Morris, A, Barton, A & Plant, D 2022, ' Pre-defined gene co-expression modules in rheumatoid arthritis transition towards molecular health following anti-TNF therapy ', Rheumatology (Oxford) . https://doi.org/10.1093/rheumatology/keac204
Background No reliable biomarkers to predict response to TNF inhibitors (TNFi) in RA patients currently exist. The aims of this study were to replicate changes in gene co-expression modules that were previously reported in response to TNFi therapy in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aabf7e1645528159a6e3e9e62c10da2
https://doi.org/10.1093/rheumatology/keac204
https://doi.org/10.1093/rheumatology/keac204
Publikováno v:
Sutcliffe, M, Barton, A & Radley, G 2020, ' Personalised medicine in rheumatic diseases : how close are we to being able to use genetic biomarkers to predict response to TNF inhibitors? ' . https://doi.org/10.1080/1744666X.2020.1740594
Introduction: A genetic biomarker to select which drug will work best for which patients with rheumatic diseases is a goal of pharmacogenetic precision medicine approaches and one that patients and the public support. However, studies of to date have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4766bdc939fcf888a25cceefdd0da56f
https://pubmed.ncbi.nlm.nih.gov/32176556
https://pubmed.ncbi.nlm.nih.gov/32176556