Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Megan S. Laham"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 995-1018 (2022)
The function of ATP binding cassette protein A1 (ABCA1) is central to cholesterol mobilization. Reduced ABCA1 expression or activity is implicated in Alzheimer's disease (AD) and other disorders. Therapeutic approaches to boost ABCA1 activity have ye
Externí odkaz:
https://doaj.org/article/24039ed219364d9b9d4d416974d46336
Autor:
Kiira M. Ratia, Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider, Nicholas Christie, Martha Ackerman-Berrier, Christopher Penton, Natalie G. Knowles, Soumya Reddy Musku, Jiqiang Fu, Ganga Reddy Velma, Rui Xiong, Gregory R. J. Thatcher
Publikováno v:
Biochemistry. 62:923-933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5010c3a8da6aacac3d71200ed29f01b
https://doi.org/10.1021/acs.biochem.2c00655
https://doi.org/10.1021/acs.biochem.2c00655
Autor:
Kiira M. Ratia, Zhengnan Shen, Jesse Gordon-Blake, Hyun Lee, Megan S. Laham, Isabella S. Krider, Nicholas Christie, Martha Ackerman-Berrier, Christopher Penton, Natalie G. Knowles, Soumya Reddy Musku, Jiqiang Fu, Ganga Reddy Velma, Rui Xiong, Gregory R J Thatcher
In aging and disease, cellular NAD+is depleted by catabolism to nicotinamide (NAM) and NAD+supple-mentation is being pursued to enhance human healthspan and lifespan. Activation of nicoti namide phosphoribosyl -transferase (NAMPT), the rate-limiting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94de410e56d30c94c873c98a4bfc088
https://doi.org/10.1101/2022.10.21.513220
https://doi.org/10.1101/2022.10.21.513220
