Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Megan Rose Paul"'
Autor:
Sunita, Sridhar, Megan Rose, Paul, Lanipua, Yeh-Nayre, Paritosh C, Khanna, Jennifer, Elster, Paula, Aristizabal, John R, Crawford
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:e21-e25
Bevacizumab-based therapies have been utilized as single or combination therapy of refractory/recurrent pediatric low-grade gliomas. Its efficacy for symptomatic cervicomedullary low-grade gliomas (cmLGGs) in the upfront and the recurrent setting is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8725de417d8d4a38750b188ec6509da1
https://doi.org/10.1097/mph.0000000000002462
https://doi.org/10.1097/mph.0000000000002462
Autor:
Mehrzad Milburn, John Robertson Crawford, Megan Rose Paul, Lanipua Yeh-Nayre, Katherine Clark Pehlivan, Jennifer D. Elster
Publikováno v:
Journal of Pediatric Hematology/Oncology. 42:e730-e737
MEK inhibitors are an emerging therapy with increasing use in mitogen-activated protein kinase-driven central nervous system (CNS) tumors. There is limited data regarding efficacy and toxicity in pediatric patients. We report our clinical experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d34e20b09e3093b09ca292b61b3b099
https://doi.org/10.1097/mph.0000000000001819
https://doi.org/10.1097/mph.0000000000001819
Publikováno v:
BMJ Case Reports. 15:e253025
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a091f3b0bbf50e6e94ec5b4d07269c0b
https://doi.org/10.1136/bcr-2022-253025
https://doi.org/10.1136/bcr-2022-253025
Publikováno v:
J Pediatr Hematol Oncol
BACKGROUND: Inotuzumab ozogamicin is a novel antibody-drug conjugate that targets CD22, a common antigen on pre-B acute lymphoblastic leukemia cells. OBSERVATIONS: A 7-year-old boy with pre-B acute lymphoblastic leukemia in his second relapse was giv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1009003f2e356388f5a35cb1f0f55127
https://doi.org/10.1097/mph.0000000000001440
https://doi.org/10.1097/mph.0000000000001440
Autor:
Jacqueline Lesperance, Pablo Tamayo, Sean Flynn, Jong Wook Kim, Nikki Phanhthilath, Peter E. Zage, Megan Rose Paul, Andrew Macias
Publikováno v:
Oncotarget. 10:6323-6333
Neuroblastoma is the most common extracranial solid tumor of childhood and accounts for 15% of all pediatric cancer-related deaths. New therapies are needed to improve outcomes for children with high-risk and relapsed tumors. Inhibitors of the RET ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece59e85bbbdcb838054d1460611e536
https://doi.org/10.18632/oncotarget.27259
https://doi.org/10.18632/oncotarget.27259
Autor:
Megan Rose Paul, Peter E. Zage
Publikováno v:
Expert review of anticancer therapy, vol 21, iss 9
Introduction: Medulloblastoma, an embryonal small round blue cell tumor primarily arising in the posterior fossa, is the most common malignancy of the central nervous system in children and requires intensive multi-modality therapy for cure. Overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9536d12aaae56ad05b31f4df73c984d7
https://pubmed.ncbi.nlm.nih.gov/34047251
https://pubmed.ncbi.nlm.nih.gov/34047251
Autor:
John R. Crawford, Megan Rose Paul, David D. Gonda, Paritosh C. Khanna, Katherine Clark Pehlivan, Jennifer D. Elster, Michael J. Levy
Publikováno v:
World neurosurgery. 150
Objective We describe our single-institutional experience with magnetic resonance−guided stereotactic laser ablation (SLA) for the treatment of newly diagnosed and recurrent pediatric brain tumors. Methods Eighteen consecutive ablation procedures w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd7c264f448d1e7926703075c763c90e
https://pubmed.ncbi.nlm.nih.gov/33722713
https://pubmed.ncbi.nlm.nih.gov/33722713
Autor:
Robert J. Wechsler-Reya, Jacqueline Lesperance, Peter E. Zage, Andrea Liu, Megan Rose Paul, Yuchen Huo, Alexandra Garancher
Publikováno v:
Neuro-oncology advances, vol 2, iss 1
Neuro-oncology Advances
Neuro-oncology Advances
Background Identifying mechanisms of medulloblastoma recurrence is a key to improving patient survival, and targeting treatment-resistant subpopulations within tumors could reduce disease recurrence. Expression of the granulocyte colony-stimulating f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa78cde830ad96961a305b3caaa1c143
https://pubmed.ncbi.nlm.nih.gov/32642714
https://pubmed.ncbi.nlm.nih.gov/32642714
Publikováno v:
The Journal of Pediatric Pharmacology and Therapeutics. 23:417-420
Vincristine is a chemotherapeutic agent with a potential toxicity of sensorimotor peripheral neuropathy. Patients receiving chemotherapy are in an immunocompromised state and may require antifungal agents. Triazole antifungals are known inhibitors of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045c7b5da66748ed7d1c5d19e7aff856
https://doi.org/10.5863/1551-6776-23.5.417
https://doi.org/10.5863/1551-6776-23.5.417
Autor:
Hamza Gorsi, Denise M. Malicki, Dennis John Kuo, Valentin Barsan, Megan Rose Paul, Jennifer D. Elster, John R. Crawford
Publikováno v:
Cureus
Cureus, vol 11, iss 12
Cureus, vol 11, iss 12
The implementation of next-generation sequencing (NGS) in pediatric neuro-oncology may impact diagnosis, prognosis, therapeutic strategies, clinical trial enrollment, and germline risk. We retrospectively analyzed 58 neuro-oncology patients (31 boys,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459b139e9f086ed58bfbe3debfc0528a
https://doi.org/10.7759/cureus.6281
https://doi.org/10.7759/cureus.6281