Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Megan R. Radler"'
Autor:
Konstantinos Nakos, Md Noor A. Alam, Megan R. Radler, Ilona A. Kesisova, Changsong Yang, Joshua Okletey, Meagan R. Tomasso, Shae B. Padrick, Tatyana M. Svitkina, Elias T. Spiliotis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(50)
Cellular morphogenesis and processes such as cell division and migration require the coordination of the microtubule and actin cytoskeletons. Microtubule–actin crosstalk is poorly understood and largely regarded as the capture and regulation of mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ace4b386dbad307ec006893f45a2ca0
https://pubmed.ncbi.nlm.nih.gov/36475946
https://pubmed.ncbi.nlm.nih.gov/36475946
Autor:
Megan R. Radler, Xiaonan Liu, Megan Peng, Brenna Doyle, Kazuhito Toyo-Oka, Elias T. Spiliotis
SummaryPyramidal neurons are the major cell type of the forebrain, consisting of a pyramidally shaped soma with axonal and apicobasal dendritic processes. It is poorly understood how the neuronal soma morphs from a sphere to pyramid, while generating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181ae7be88f51cd676b77828006baa00
https://doi.org/10.1101/2022.06.19.496721
https://doi.org/10.1101/2022.06.19.496721
Autor:
Konstantinos Nakos, Megan R. Radler, Ilona A. Kesisova, Meagan R. Tomasso, Shae B. Padrick, Elias T. Spiliotis
Cellular morphogenesis and processes such as cell division and migration require the coordination of the microtubule and actin cytoskeletons (1, 2). Microtubule-actin crosstalk is poorly understood and largely regarded as the capture and regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fabb2d764c0b5c5cd8ed83f0c048195
https://doi.org/10.1101/2022.02.15.480618
https://doi.org/10.1101/2022.02.15.480618
Autor:
Megan R. Radler, Elias T. Spiliotis
Publikováno v:
Current opinion in neurobiology. 75
Neuronal morphogenesis is guided by outside-in signals and inside-out mechanisms, which require spatiotemporal precision. How the intracellular mechanisms of neuronal morphogenesis are spatiotemporally controlled is not well understood. Septins compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dedc19ed136ea17832abadc50991060b
https://pubmed.ncbi.nlm.nih.gov/35609489
https://pubmed.ncbi.nlm.nih.gov/35609489
Publikováno v:
Molecular Biology of the Cell
Septins (SEPTs) are filamentous guanosine-5′-triphosphate (GTP)-binding proteins, which affect microtubule (MT)-dependent functions including membrane trafficking and cell division, but their precise role in MT dynamics is poorly understood. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b3eb90e4ec6815bb85dca7e401157b
https://doi.org/10.1091/mbc.e19-07-0362
https://doi.org/10.1091/mbc.e19-07-0362
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 103(6)
We designed a dicistronic plastid marker system that relies on the plastid's ability to translate polycistronic mRNAs. The identification of transplastomic clones is based on selection for antibiotic resistance encoded in the first open reading frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5e3d721005f6aef58bb7be00f4d4c8
https://pubmed.ncbi.nlm.nih.gov/32497322
https://pubmed.ncbi.nlm.nih.gov/32497322
Septins are filamentous GTP-binding proteins, which affect microtubule (MT) dependent functions including membrane trafficking and cell division, but their precise role in MT dynamics is poorly understood. Here, in vitro reconstitution of MT dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64ba09e7fc0a9c61fbca9084b3cac58
Autor:
Shawn M. Egan, Scott H. Olejniczak, Qing Xiang, Megan R. Radler, Gaspare La Rocca, Craig B. Thompson, Ralph Garippa
Publikováno v:
Molecular and Cellular Biology. 36:2360-2373
Cell growth and proliferation require the coordinated activation of many cellular processes, including cap-dependent mRNA translation. MicroRNAs oppose cap-dependent translation and set thresholds for expression of target proteins. Emerging data sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae806f62809d7cc94ed3c9c94ff6f0c1
https://doi.org/10.1128/mcb.01011-15
https://doi.org/10.1128/mcb.01011-15
Publikováno v:
Mol Cell Neurosci
Neuronal dendrites are highly branched and specialized compartments with distinct structures and secretory organelles (e.g., spines, Golgi outposts), and a unique cytoskeletal organization that includes microtubules of mixed polarity. Dendritic membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128894961b0282c13abc330e79c63065
https://doi.org/10.1016/j.mcn.2020.103492
https://doi.org/10.1016/j.mcn.2020.103492
Autor:
Lee Spraggon, Daniel Briskin, Joana A. Vidigal, Raymond G. DeMatteo, Gaspare La Rocca, Thomas Tuschl, Craig B. Thompson, Megan R. Radler, Andrea Ventura, Tullia Lindsten, Alvaro J. González, Scott H. Olejniczak, Christina S. Leslie
Publikováno v:
Proceedings of the National Academy of Sciences. 112:767-772
MicroRNAs repress mRNA translation by guiding Argonaute proteins to partially complementary binding sites, primarily within the 3' untranslated region (UTR) of target mRNAs. In cell lines, Argonaute-bound microRNAs exist mainly in high molecular weig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add020a3b0727bbc0d6619621a469aa2
https://doi.org/10.1073/pnas.1424217112
https://doi.org/10.1073/pnas.1424217112