Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Megan Peasley"'
Autor:
Andrew Berical, Rhianna E. Lee, Junjie Lu, Mary Lou Beermann, Jake A. Le Suer, Aditya Mithal, Dylan Thomas, Nicole Ranallo, Megan Peasley, Alex Stuffer, Katherine Bukis, Rebecca Seymour, Jan Harrington, Kevin Coote, Hillary Valley, Killian Hurley, Paul McNally, Gustavo Mostoslavsky, John Mahoney, Scott H. Randell, Finn J. Hawkins
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Hundreds of mutations in the gene CFTR lead to cystic fibrosis and represent a challenge to developing therapeutics. Here, authors demonstrate the ability of airway cells derived from human iPSCs to model genotype-specific CFTR function as well as ph
Externí odkaz:
https://doaj.org/article/850dff2dec12496d9eba80d2cebdd541
Autor:
Aditya Mithal, Amalia Capilla, Dar Heinze, Andrew Berical, Carlos Villacorta-Martin, Marall Vedaie, Anjali Jacob, Kristine Abo, Aleksander Szymaniak, Megan Peasley, Alexander Stuffer, John Mahoney, Darrell N. Kotton, Finn Hawkins, Gustavo Mostoslavsky
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Human induced pluripotent stem cell-derived intestinal organoids (HIOs) are powerful tools to study development and diseases of the gastrointestinal tract. Here, the authors develop a directed differentiation protocol to generate mesenchyme-free HIOs
Externí odkaz:
https://doaj.org/article/efa815c9f57c43c1a9355336f273c3c9
Autor:
Finn Hawkins, Amalia Capilla, Aleksander D. Szymaniak, Alexander Stuffer, Marall Vedaie, Dar Heinze, Aditya Mithal, Carlos Villacorta-Martin, Gustavo Mostoslavsky, Darrell N. Kotton, Megan Peasley, Kristine M. Abo, John Mahoney, Anjali Jacob, Andrew Berical
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Efficient generation of human induced pluripotent stem cell (hiPSC)-derived human intestinal organoids (HIOs) would facilitate the development of in vitro models for a variety of diseases that affect the gastrointestinal tract, such as inflammatory b