Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Megan Pavy"'
Autor:
Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur, Sarah L. Teakel, Ashleigh Van Oosterum, Ishith Seth, Marina Pajic, Katherine M. Hannan, Megan Pavy, Perlita Poh, Jalal A. Jazayeri, Thiri Zaw, Dana Pascovici, Marina Ludescher, Michael Pawlak, Juan C. Cassano, Lynne Turnbull, Mitra Jazayeri, Alexander C. James, Craig P. Coorey, Tara L. Roberts, Simon J. Kinder, Ross D. Hannan, Ellis Patrick, Mark P. Molloy, Elizabeth J. New, Tanja N. Fehm, Hans Neubauer, Ewa M. Goldys, Leslie A. Weston, Michael A. Cahill
Publikováno v:
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Abstract Background Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. It contains phosphorylated tyrosines which evolutionarily preceded deuterostome gastr
Externí odkaz:
https://doaj.org/article/2bd658d87bfa450aac0f899967a1efce
Publikováno v:
Tobacco Prevention & Cessation. 8:1-5
Brick-and-mortar vape shops have increased in recent years, but there is limited research on the types of marketing claims consumers are exposed to on their websites - a dominant channel for marketing electronic nicotine delivery systems (ENDS). We i
Autor:
Ross D. Hannan, Priscilla Soo, Yen Thi-Hoang Vo, Michael G. Gardiner, Madushani Amarasiri, Rita Ferreira, Martin G. Banwell, Nadine Hein, Katherine M. Hannan, Megan Pavy, Perlita Poh
Publikováno v:
Australian Journal of Chemistry. 74:540-556
The regio-isomeric alkynyl-substituted derivatives, 2 and 3, of the RNA Polymerase I (Pol I) transcription inhibitor CX-5461 (1) were prepared and the active one (compound 3) subjected to click reactions ([3 + 2]-cycloaddition reactions) with certain
Autor:
Katherine M. Hannan, Priscilla Soo, Mei S. Wong, Justine K. Lee, Nadine Hein, Perlita Poh, Kira D. Wysoke, Tobias D. Williams, Christian Montellese, Lorey K. Smith, Sheren J. Al-Obaidi, Lorena Núñez-Villacís, Megan Pavy, Jin-Shu He, Kate M. Parsons, Karagh E. Loring, Tess Morrison, Jeannine Diesch, Gaetan Burgio, Rita Ferreira, Zhi-Ping Feng, Cathryn M. Gould, Piyush B. Madhamshettiwar, Johan Flygare, Thomas J. Gonda, Kaylene J. Simpson, Ulrike Kutay, Richard B. Pearson, Christoph Engel, Nicholas J. Watkins, Ross D. Hannan, Amee J. George
Publikováno v:
Cell reports. 41(5)
The nucleolar surveillance pathway monitors nucleolar integrity and responds to nucleolar stress by mediating binding of ribosomal proteins to MDM2, resulting in p53 accumulation. Inappropriate pathway activation is implicated in the pathogenesis of
Autor:
Egi Kardia, Omid Fakhri, Megan Pavy, Hugh Mason, Nina Huang, Elena Smertina, Mary K. Estes, Tanja Strive, Michael Frese, Robyn N. Hall
Lagoviruses, family Caliciviridae, are some of the most virulent vertebrate viruses known. They infect leporids, i.e., rabbits (Oryctolagus spp.), hares (Lepus spp.) and cottontails (Sylvilagus spp.) and rapidly kill over 95% of susceptible animals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a7bb4d210a3d702c62135e4394225a4
https://doi.org/10.1101/2022.04.07.487566
https://doi.org/10.1101/2022.04.07.487566
Autor:
Ross D. Hannan, Tanja Fehm, Partho P. Adhikary, Ishith Seth, Ewa M. Goldys, Alexander James, Marina Pajic, Elizabeth J. New, Juan C. Cassano, Megan Pavy, Craig P. Coorey, Leslie A. Weston, Mitra Jazayeri, Sarah L. Teakel, Simon J. Kinder, Lynne Turnbull, Mark P. Molloy, Ashleigh Van Oosterum, Dana Pascovici, Ellis Patrick, Hans Neubauer, Michael Pawlak, Tara L. Roberts, Michael A. Cahill, Bashar M. Thejer, Jalal A. Jazayeri, Amandeep Kaur, Katherine M. Hannan, Marina Ludescher, Thiri Zaw, Perlita Poh
Publikováno v:
BMC Molecular and Cell Biology
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-24 (2020)
BMC Molecular and Cell Biology, Vol 21, Iss 1, Pp 1-24 (2020)
Background Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. It contains phosphorylated tyrosines which evolutionarily preceded deuterostome gastrulation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4de00d56a22e934f8adfe291e000118
Autor:
Justine K. Lee, Ulrike Kutay, Sheren Al-Obaidi, Mei S. Wong, Priscilla Soo, Lorena Núñez-Villacís, Christian Montellese, Ross D. Hannan, Rita Ferreira, Kate M Parsons, Amee J George, Gaetan Burgio, Kaylene J. Simpson, Christoph Engel, Nicholas J. Watkins, Katherine M. Hannan, Tobias D. Williams, Johan Flygare, Cathryn M. Gould, Kira D. Wysoke, Maurits Evers, Zhi-Ping Feng, Thomas J. Gonda, Lorey K. Smith, Nadine Hein, Richard B. Pearson, Jeannine Diesch, Perlita Poh, Piyush B. Madhamshettiwar, Megan Pavy, Jin-Shu He
The nucleolar surveillance pathway (NSP) monitors nucleolar fidelity and responds to nucleolar stresses (i.e., inactivation of ribosome biogenesis) by mediating the inhibitory binding of ribosomal proteins (RPs) to mouse double minute 2 homolog (MDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f004f573c723ed975ca1ebf9c31b2e
https://doi.org/10.1101/2021.01.21.427535
https://doi.org/10.1101/2021.01.21.427535
Autor:
Rituparna Mittra, Richard Callaghan, Nandhitha Subramanian, Anthony M. George, Megan L. O'Mara, Megan Pavy, Ian D. Kerr
Publikováno v:
Biochemical Pharmacology. 123:19-28
© 2016 Elsevier Inc. The multidrug resistance P-glycoprotein (P-gp) is characterised by the ability to bind and/or transport an astonishing array of drugs. This poly-specificity is imparted by at least four pharmacologically distinct binding sites w
Autor:
Partho P. Adhikary, Juan C. Cassano, Bashar M. Thejer, Alexander James, Ross D. Hannan, Katherine M. Hannan, Michael Pawlak, Ellis Patrick, Simon J. Kinder, Amandeep Kaur, Marina Ludescher, Elizabeth J. New, Ashleigh Van Oosterum, Ewa M. Goldys, Dana Pascovici, Ishith Seth, Lynne Turnbull, Jalal A. Jazayeri, Mark P. Molloy, Megan Pavy, Craig P. Coorey, Mitra Jazayeri, Thiri Zaw, Perlita Poh, Sarah L. Teakel, Leslie A. Weston, Hans Neubauer, Tara L. Roberts, Marina Pajic, Michael A. Cahill, Tanja Fehm
Background: Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a varie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd5b95fd7918a256bd5c09bc3526dff
Autor:
Grant A. McArthur, James D. Rozario, Meaghan Wall, Denis Drygin, Gretchen Poortinga, Adele Baker, Ross D. Hannan, Donald P. Cameron, Katherine M. Hannan, Carleen Cullinane, Johannes Zuber, Mark A. Guthridge, Jennifer R. Devlin, Elaine Sanij, Jirawas Sornkom, Mark A. Dawson, Nadine Hein, Nhu Y.N. Nguyen, Amee J George, Chun Yew Fong, Simon J. Harrison, Ricky W. Johnstone, Jaclyn E Quin, Megan Pavy, Jeannine Diesch, Richard B. Pearson, Inge Verbrugge, Stuart M. Pitson, Jason A. Powell, Andrew H. Wei
Publikováno v:
Blood. 129(21)
Despite the development of novel drugs, the prospects for many patients with acute myeloid leukemia (AML) remain dismal. This study reveals that the selective inhibitor of RNA polymerase I (Pol I) transcription, CX-5461, effectively treats aggressive