Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Megan P. Wood"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2643-2654 (2016)
Complexes of RNA and RNA binding proteins form large-scale supramolecular structures under many cellular contexts. In Caenorhabditis elegans, small germ granules are present in the germ line that share characteristics with liquid droplets that underg
Externí odkaz:
https://doaj.org/article/f5fc2811875c4a04a158b18d0722358a
Autor:
Matthew Warburton, Megan L. Wood, Kuldeep Sohal, John Wright, Mark Mon-Williams, Amy L. Atkinson
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Not being in employment, education, or training (NEET) is associated with poor health (physical and mental) and social exclusion. We investigated whether England’s statutory school readiness measure conducted at 4–5 years prov
Externí odkaz:
https://doaj.org/article/e2dc68e9263a401c898162c530e3b775
Publikováno v:
Royal Society Open Science, Vol 11, Iss 6 (2024)
Post-pandemic school absence is an increasing concern for governments worldwide. Absence is associated with poor academic outcomes and long-term illness (physical and mental). Absenteeism increases the risk of financial difficulties in adulthood and
Externí odkaz:
https://doaj.org/article/af2e23d8c59a4463b4ebee289b29dbd7
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
In addition to hearing loss, damage to the cochlea can lead to gain of function pathologies such as hyperacusis. It has been proposed that painful hyperacusis, noxacusis, may be carried to the central nervous system by type II cochlear afferents, spa
Externí odkaz:
https://doaj.org/article/264f6899bcaf40b7866ef06a7be5934a
Autor:
Yuanyuan Zhang, Hakim Hiel, Philippe F.Y. Vincent, Megan B. Wood, Ana B. Elgoyhen, Wade Chien, Amanda Lauer, Paul A. Fuchs
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 17-31 (2023)
Efferent brain-stem neurons release acetylcholine to desensitize cochlear hair cells and can protect the inner ear from acoustic trauma. That protection is absent from knockout mice lacking efferent inhibition and is stronger in mice with a gain-of-f
Externí odkaz:
https://doaj.org/article/a79bc30c2bc9499087ccecdc63b17e25
Autor:
Nicola Laura Diny, Megan Kay Wood, Taejoon Won, Monica Vladut Talor, Clarisse Lukban, Djahida Bedja, Nadan Wang, Hannah Kalinoski, Abdel Daoud, C. Conover Talbot, Jr., Brian Leei Lin, Daniela Čiháková
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107990- (2023)
Summary: Hypereosinophilic syndrome is a progressive disease with extensive eosinophilia that results in organ damage. Cardiac pathologies are the main reason for its high mortality rate. A better understanding of the mechanisms of eosinophil-mediate
Externí odkaz:
https://doaj.org/article/30640f6bca3044d2b937414794d30d52
Autor:
Dan Mason, Liam JB Hill, Richard J Allen, Katy A. Shire, Amanda H Waterman, Megan L Wood, Kirsty Crossley
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: Cognitive ability and sensorimotor function are crucial aspects of children’s development, and are associated with physical and mental health outcomes and educational attainment. This paper describes cross-sectional sensorimotor and cog
Externí odkaz:
https://doaj.org/article/145f431bd38247e892d0025a97eef56e
Autor:
Xuezhou Hou, Guobao Chen, William Bracamonte-Baran, Hee Sun Choi, Nicola L. Diny, Jungeun Sung, David Hughes, Taejoon Won, Megan Kay Wood, Monica V. Talor, David Joel Hackam, Karin Klingel, Giovanni Davogustto, Heinrich Taegtmeyer, Isabelle Coppens, Jobert G. Barin, Daniela Čiháková
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 172-189.e7 (2019)
Summary: Two types of monocytes, Ly6Chi and Ly6Clo, infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6Chi and Ly6Cl
Externí odkaz:
https://doaj.org/article/b6b5be67eb354a43a097237f7256ed86
Publikováno v:
American Journal of Physiology-Cell Physiology. 312:C741-C748
Cells respond to environmental stress in multiple ways. In the germ line, heat shock and nutritive stress trigger the assembly of large ribonucleoprotein (RNP) granules via liquid-liquid phase separation (LLPS). The RNP granules are hypothesized to m
Autor:
Jennifer A Schisa, Alexandra Couch, Joseph Robert Patterson, Shaughna Langerak, Alicia Trombley, Devon Leroux, Megan P Wood
Publikováno v:
genesis. 57
A key aspect of development in all metazoans is remodeling at the cellular level. During the development of gametes, remodeling occurs throughout the germ line. When Caenorhabditis elegans hermaphrodites become depleted of sperm after 4 days of adult