Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Megan P Hitchins"'
Autor:
Maria Christensen, Andrew E Hendifar, Rachel Pearlman, Sigurdis Haraldsdottir, Albert de la Chapelle, Heather Hampel, Megan P Hitchins, Ingrid P Vogelaar, Kevin Brennan, Nianmin Zhou, Brock Martin, Rocio Alvarez, Xiaopu Yuan, Sungjin Kim, Maha Guindi, Matthew F Kalady, Jennifer DeVecchio, James M Church, Carrie Snyder, Stephen J Lanspa, Robert W Haile, Henry T Lynch
Publikováno v:
BMJ Open Gastroenterology, Vol 6, Iss 1 (2019)
Objective The plasma-based methylated SEPTIN9 (mSEPT9) is a colorectal cancer (CRC) screening test for adults aged 50–75 years who are at average risk for CRC and have refused colonoscopy or faecal-based screening tests. The applicability of mSEPT9
Externí odkaz:
https://doaj.org/article/9cc419266d314d61ad0f4bf7e132d705
Publikováno v:
Journal of Gastrointestinal Oncology. 14:1175-1177
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85ee198d13f61c1f5429b716ceb4b250
https://doi.org/10.21037/jgo-23-12
https://doi.org/10.21037/jgo-23-12
Autor:
Holli A. Loomans-Kropp, Yurong Song, Manish Gala, Aparna R. Parikh, Emily E. Van Seventer, Rocio Alvarez, Megan P. Hitchins, Robert H. Shoemaker, Asad Umar
Publikováno v:
Cancer Res Commun
Early-onset colorectal cancer (EOCRC), defined as a diagnosis under age 50, is an emerging public health burden. As many of these individuals fall outside of screening guidelines, the development of a minimally invasive, accurate screening modality f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818008589f689007223568cb8f9ce4fe
https://doi.org/10.1158/2767-9764.crc-21-0142
https://doi.org/10.1158/2767-9764.crc-21-0142
Autor:
John Burn, Megan P. Hitchins
Related Articles from Alu in Lynch Syndrome: A Danger SINE?
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1289ec30d7af2837245ff4eb10790298
https://doi.org/10.1158/1940-6207.22527057.v1
https://doi.org/10.1158/1940-6207.22527057.v1
Autor:
Robyn L. Ward, Megan P. Hitchins
Related Article from Favoritism in DNA Methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbdb5f43201833e67af4ed41699ad15
https://doi.org/10.1158/1940-6207.22523410
https://doi.org/10.1158/1940-6207.22523410
Autor:
John Burn, Megan P. Hitchins
Lynch syndrome is a hereditary cancer predisposition syndrome caused by germline loss of a DNA mismatch repair gene. In a significant proportion of cases, loss of function of the MSH2 mismatch repair gene is caused by large heterogeneous deletions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5df89c35c48951cc32501476f7a8de70
https://doi.org/10.1158/1940-6207.c.6545313.v1
https://doi.org/10.1158/1940-6207.c.6545313.v1
Autor:
Megan P. Hitchins, Nicholas J. Hawkins, Jake Olivier, Mark A. Jenkins, John L. Hopper, Ingrid M. Winship, Melissa C. Southey, Christophe Rosty, Mark Clendenning, Aung Ko Win, Daniel D. Buchanan, Robyn L. Ward, Robert W. Rapkins, Fan Wang, Joice Kuroiwa-Trzmielina
Supplementary Table 1. Statistical comparisons between the methylation status of the MGMT promoter within colorectal carcinoma (CRC) and clinicopathological features, molecular features of tumors, and rs16906252C>T genotype in cases from the Sydney C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2469ef735dfa1a889cc8e5d16976cac4
https://doi.org/10.1158/1078-0432.22467920.v1
https://doi.org/10.1158/1078-0432.22467920.v1
Autor:
Megan P. Hitchins, Nicholas J. Hawkins, Jake Olivier, Mark A. Jenkins, John L. Hopper, Ingrid M. Winship, Melissa C. Southey, Christophe Rosty, Mark Clendenning, Aung Ko Win, Daniel D. Buchanan, Robyn L. Ward, Robert W. Rapkins, Fan Wang, Joice Kuroiwa-Trzmielina
Purpose: Methylation of the MGMT promoter is the major cause of O6-methylguanine methyltransferase deficiency in cancer and has been associated with the T variant of the promoter enhancer SNP rs16906252C>T. We sought evidence for an association betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6800beddc8eddf4c5c4b447ca415e6a6
https://doi.org/10.1158/1078-0432.c.6526787.v1
https://doi.org/10.1158/1078-0432.c.6526787.v1
Autor:
Megan P. Hitchins, Nicholas J. Hawkins, Jake Olivier, Mark A. Jenkins, John L. Hopper, Ingrid M. Winship, Melissa C. Southey, Christophe Rosty, Mark Clendenning, Aung Ko Win, Daniel D. Buchanan, Robyn L. Ward, Robert W. Rapkins, Fan Wang, Joice Kuroiwa-Trzmielina
Supplementary methods providing additional technical detail for methods that is relevant only to those who wish to repeat them exactly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1fef49e0233a3113cfa7b799704b2c
https://doi.org/10.1158/1078-0432.22467923.v1
https://doi.org/10.1158/1078-0432.22467923.v1
Autor:
Megan P. Hitchins, Nicholas J. Hawkins, Jake Olivier, Mark A. Jenkins, John L. Hopper, Ingrid M. Winship, Melissa C. Southey, Christophe Rosty, Mark Clendenning, Aung Ko Win, Daniel D. Buchanan, Robyn L. Ward, Robert W. Rapkins, Fan Wang, Joice Kuroiwa-Trzmielina
Supplementary Figure 1. Allele quantification assays used to measure relative levels of mRNA expression at exonic SNPs within MGMT. Supplementary Figure 2. Allelic expression ratios of MGMT transcripts in the normal colorectal mucosa (NCM) of colorec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb49e99f25408e8b7b3f543dd3b2ac5a
https://doi.org/10.1158/1078-0432.22467926.v1
https://doi.org/10.1158/1078-0432.22467926.v1