Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Megan N. Sandberg"'
Autor:
Jordan A. Greco, Nicole L. Wagner, Ralph J. Jensen, Daniel J. Sandberg, Matthew J. Ranaghan, Megan N. Sandberg, Robert R. Birge, Daniel B Lawrence
Publikováno v:
J Neural Eng
Objective. Biomimetic protein-based artificial retinas offer a new paradigm for restoring vision for patients blinded by retinal degeneration. Artificial retinas, comprised of an ion-permeable membrane and alternating layers of bacteriorhodopsin (BR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2b71a112813296b1ab10abe3c760bd
https://europepmc.org/articles/PMC8666970/
https://europepmc.org/articles/PMC8666970/
Autor:
Robert R. Birge, Lavoisier Ramos, Barry E. Knox, Megan N. Sandberg, Min-Hsuan Chen, Tabitha L. Amora
Publikováno v:
Journal of the American Chemical Society. 133:2808-2811
Assignment of the protonation state of the residue Glu-181 is important to our understanding of the primary event, activation processes and wavelength selection in rhodopsin. Despite extensive study, there is no general agreement on the protonation s
Autor:
Harry A. Frank, George N. Gibson, Daniel J. Sandberg, Dariusz M. Niedzwiedzki, Megan N. Sandberg, Hong Cong, Robert R. Birge
Publikováno v:
Chemical Physics. 357:4-16
The structures of a number of stereoisomers of carotenoids have been revealed in three-dimensional X-ray crystallographic investigations of pigment–protein complexes from photosynthetic organisms. Despite these structural elucidations, the reason f
Autor:
Jordan A. Greco, Min-Hsuan Chen, Barry E. Knox, Megan N. Sandberg, Lavoisier A. Ramos, Nicole L. Wagner, Tabitha L. Amora, Robert R. Birge
Publikováno v:
SOJ Biochemistry. 1
Three active-site components in rhodopsin play a key role in the stability and function of the protein: 1) the counter-ion residues which stabilize the protonated Schiff base, 2) water molecules, and 3) the hydrogen-bonding network. The ionizable res
Publikováno v:
Biochemistry. 52(30)
Visual pigments have a conserved phenylalanine in transmembrane helix 5 located near the β-ionone ring of the retinal chromophore. Site-directed mutants of this residue (F207) in a short-wavelength sensitive visual pigment (VCOP) were studied using
Autor:
Matthias Zeller, Pedro Daddario, Jason R. McCarthy, Christopher J. Ziegler, Michael A. Hyland, Megan N. Sandberg, Jill L. Worlinsky, Robert R. Birge, Matthew J. Ranaghan, Christian Brückner, James T. Engle, Joshua Akhigbe, Junichi Ogikubo
Publikováno v:
The Journal of organic chemistry. 77(15)
The rational syntheses of meso-tetraaryl-3-oxo-2-oxaporphyrins 5, known as porpholactones, via MnO(4)(-)-mediated oxidations of the corresponding meso-tetraaryl-2,3-dihydroxychlorins (7) is detailed. Since chlorin 7 is prepared from the parent porphy
From kinematics to molecular machines, biologically inspired technologies harness and enhance the intrinsic properties of naturally occurring materials and systems for applied technologies. Bacteriorhodopsin (BR) represents the most studied protein f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b835d70e4acd0d823c64c10910967efe
https://doi.org/10.1533/9780857097651.20
https://doi.org/10.1533/9780857097651.20
Vision in vertebrates is a complex and involved process. Small organic molecules, known as chromophores, become electronically excited upon the absorption of a photon of light. In the excited state exists a barrier-less potential energy surface for s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a7f0e357614f19d263924cf970aecb7
https://doi.org/10.1016/b978-0-12-374920-8.00913-9
https://doi.org/10.1016/b978-0-12-374920-8.00913-9
Autor:
Barry E. Knox, Arjun Surya, Kunnel R. Babu, Jhenny F. Galan, Robert R. Birge, Lavoisier Ramos, Min-Hsuan Chen, Daniel J. Sandberg, José Bubis, Heidi J. Zapata, Megan N. Sandberg
Publikováno v:
Biochemistry. 50(32)
The role of the extracellular loop region of a short-wavelength sensitive pigment, Xenopus violet cone opsin, is investigated via computational modeling, mutagenesis, and spectroscopy. The computational models predict a complex H-bonding network that
Autor:
Dariusz M, Niedzwiedzki, Daniel J, Sandberg, Hong, Cong, Megan N, Sandberg, George N, Gibson, Robert R, Birge, Harry A, Frank
Publikováno v:
Chemical physics. 357(1)
The structures of a number of stereoisomers of carotenoids have been revealed in three-dimensional X-ray crystallographic investigations of pigment-protein complexes from photosynthetic organisms. Despite these structural elucidations, the reason for