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of 9
pro vyhledávání: '"Megan N Nash"'
Autor:
Sashika N Richards, Megan N Nash, Eileen S Baker, Michael W Webster, Adele M Lehane, Sarah H Shafik, Rowena E Martin
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005725 (2016)
Mutations in the Plasmodium falciparum 'chloroquine resistance transporter' (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite's digesti
Externí odkaz:
https://doaj.org/article/c5c24d1b429c4890955f2192f5a69ecb
Publikováno v:
Int J Audiol
OBJECTIVE: The objective was to determine the relative contribution of four criteria (loudness, annoyance, distraction, speech interference) to participants’ noise-tolerance thresholds (NTT). DESIGN: While listening to speech in noise set at the hi
Autor:
Brienna Maestas, Chloe A. Liu, Megan N. Nash, Catherine C. Culver, Kristine U. Layugan, David Kurahara, Jennifer King
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 96:e219-e222
Hypermobility syndrome usually causes pain in limbs from extension type injuries. The authors report on a 16-yr-old female adolescent with incapacitating chest pain secondary to extreme hypermobility of the chest. This pain led the patient to see mul
Autor:
Rowena E. Martin, Max Meyrath, Megan N. Nash, Wilfred D. Stein, Robert L. Summers, Sebastiano Bellanca, Michael Lanzer, Anurag Dave, Martin Dittmer, Cecilia P. Sanchez
Publikováno v:
The Journal of Biological Chemistry
Background: Mutations in the chloroquine resistance transporter (PfCRT) change the susceptibility of Plasmodium falciparum to diverse antimalarial drugs. Results: In addition to chloroquine, PfCRT transports quinine, quinidine, and verapamil, which b
Autor:
Vanessa Winchester, Megan N. Nash, Samuel Clemmens, Jammie Valdivia Cerda, Olaf Wündrich, Martin Sessions, Neil F. Glasser
Publikováno v:
Geografiska Annaler: Series A, Physical Geography. 96:43-59
Glacier Benito is a temperate outlet glacier on the west side of the North Patagonian Icefield. Rates of thinning and ablation were obtained using data collected by the British Joint Services Expedition in 1972/73 and subsequent data collected in 200
Autor:
Adele M. Lehane, Megan N. Nash, Michael W. Webster, Rowena E. Martin, Sarah H. Shafik, Sashika N. Richards, Eileen S. Baker
Publikováno v:
PLoS Pathogens, Vol 12, Iss 7, p e1005725 (2016)
PLoS Pathogens
PLoS Pathogens
Mutations in the Plasmodium falciparum ‘chloroquine resistance transporter’ (PfCRT) confer resistance to chloroquine (CQ) and related antimalarials by enabling the protein to transport these drugs away from their targets within the parasite’s d
Publikováno v:
Cellular and Molecular Life Sciences. 69:1967-1995
The prevention and treatment of malaria is heavily dependent on antimalarial drugs. However, beginning with the emergence of chloroquine (CQ)-resistant Plasmodium falciparum parasites 50 years ago, efforts to control the disease have been thwarted by
Autor:
Pete Smith, Sarah H. Shafik, Robert L. Summers, Adele M. Lehane, Donelly A. van Schalkwyk, Megan N. Nash, Rowena E. Martin
Publikováno v:
The Journal of infectious diseases. 213(5)
It is becoming increasingly apparent that certain mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) alter the parasite's susceptibility to diverse compounds. Here we investigated the interaction of PfCRT with 3 tricycl
Autor:
Michael Lanzer, Robert L. Summers, Sashika N. Richards, Wilfred D. Stein, Kiaran Kirk, Rowena E. Martin, Megan N. Nash, Tegan J. Dolstra, Valerie Goh, Rosa V. Marchetti, Cecilia P. Sanchez, Anurag Dave, Robyn L. Schenk, Sebastiano Bellanca
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(17)
Mutations in the chloroquine resistance transporter (PfCRT) are the primary determinant of chloroquine (CQ) resistance in the malaria parasite Plasmodium falciparum. A number of distinct PfCRT haplotypes, containing between 4 and 10 mutations, have g