Decreased expression of caveolin 1 in patients with systemic sclerosis: Crucial role in the pathogenesis of tissue fibrosis

Autor: Megan Musick, Sergio A. Jimenez, Francesco Del Galdo, Cecilia J. de Almeida, Jean-Francois Jasmin, Federica Sotgia, Michael P. Lisanti

Publikováno v: Del Galdo, F, Sotgia, F, De Almeida, C J, Jasmin, J F, Musick, M, Lisanti, M P & Jiménez, S A 2008, ' Decreased expression of caveolin 1 in patients with systemic sclerosis: Crucial role in the pathogenesis of tissue fibrosis ', Arthritis Care & Research, vol. 58, no. 9, pp. 2854-2865 . https://doi.org/10.1002/art.23791

Objective. Recent studies have implicated caveolin 1 in the regulation of transforming growth factor β (TGFβ) downstream signaling. Given the crucial role of TGFβ in the pathogenesis of systemic sclerosis (SSc), we sought to determine whether cave

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https://doi.org/10.1002/art.23791