Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Megan Moerdyk-Schauwecker"'
Autor:
Ashleigh Everhardt Queen, Megan Moerdyk-Schauwecker, Leslie M McKee, Larry J Leamy, Yvette M Huet
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152289 (2016)
Sex plays a key role in an individual's immune response against pathogenic challenges such that females fare better when infected with certain pathogens. It is thought that sex hormones impact gene expression in immune cells and lead to sexually dimo
Externí odkaz:
https://doaj.org/article/ad4f8fcb60ab4ccd96548e30f5a9e5c4
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104688 (2014)
Virus particles (virions) often contain not only virus-encoded but also host-encoded proteins. Some of these host proteins are enclosed within the virion structure, while others, in the case of enveloped viruses, are embedded in the host-derived memb
Externí odkaz:
https://doaj.org/article/83425b82c3b9488aa5f2cd8c0f44879b
Autor:
Nury Steuerwald, Valery Z. Grdzelishvili, Eric Hastie, Megan Moerdyk-Schauwecker, Sébastien A. Felt, Marcela Cataldi
Publikováno v:
Oncotarget
// Eric Hastie 1, * , Marcela Cataldi 1, * , Megan J. Moerdyk-Schauwecker 1, * , Sebastien A. Felt 1, * , Nury Steuerwald 2 , Valery Z. Grdzelishvili 1 1 Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA
Autor:
Vinita S. Chauhan, Alejandra N. Martinez, Ian D. Cooley, Mario T. Philipp, Ada D. Young, Geeta Ramesh, Ian Marriott, M. Brittany Johnson, Amanda R. Burmeister, Megan Moerdyk-Schauwecker
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Background The tachykinin substance P (SP) is recognized to exacerbate inflammation at peripheral sites via its target receptor, neurokinin 1 receptor (NK-1R), expressed by leukocytes. More recently, SP/NK-1R interactions have been associated with se
Autor:
Jennifer M. Curry, Nirav Shah, Dahlia M. Besmer, Eric Hastie, Pinku Mukherjee, Andrea M. Murphy, Lopamudra Das Roy, Valery Z. Grdzelishvili, Megan Moerdyk-Schauwecker, Carlos Molestina
Publikováno v:
Journal of Virology. 87:10283-10294
Vesicular stomatitis virus (VSV) is a promising oncolytic agent against various malignancies. Here, for the first time, we tested VSV in vitro and in vivo in a clinically relevant, immunocompetent mouse model of pancreatic ductal adenocarcinoma (PDA)
Publikováno v:
Glia. 58:1620-1629
While astrocytes produce key inflammatory mediators following exposure to neurotropic nonsegmented negative-sense RNA viruses such as rabies virus and measles virus, the mechanisms by which resident central nervous system (CNS) cells perceive such vi
Autor:
Valery Z. Grdzelishvili, Megan Moerdyk-Schauwecker, Daniel A. Nelson, Vinita S. Chauhan, Ian Marriott, Samantha R. Furr, David Sterka
Publikováno v:
Virology. 400:187-196
Vesicular stomatitis virus (VSV) infection of mice via intranasal administration results in a severe encephalitis with rapid activation and proliferation of microglia and astrocytes. We have recently shown that these glial cells express RIG-I and MDA
Autor:
Peregrine L. Wolff, Ling Jin, Colin M. Gillin, Kimberly A. Thompson, Robert J. Bildfell, Megan Moerdyk-Schauwecker
Publikováno v:
Journal of Wildlife Diseases. 46:33-45
The pathogenic potential of deerpox virus was investigated via an experimental study utilizing seven black-tailed deer fawns (Odocoileus hemionus) between June and August of 2007. Successful transmission was achieved via intracutaneous and intravenou
Autor:
Ling Jin, Kathleen Eide, Robert E. Blouch, Robert J. Bildfell, Patrick L. Iversen, David A. Stein, Megan Moerdyk-Schauwecker
Publikováno v:
Antiviral Research. 84:131-141
Alternative therapies are needed for HSV-1 infections in patients refractory to treatment with Acyclovir (ACV) and its derivatives. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) are single-stranded DNA analogues that enter cells r
Autor:
Graham Crawshaw, Kathleen Eide, Wendy Black, Rocky J. Baker, Ling Jin, Megan Moerdyk-Schauwecker, George F. Rohrmann, Robert J. Bildfell, Daniel Graham, Kim Thompson
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 21:487-492
The present report describes the analysis of 4 Deerpox virus isolates from California, Oregon, and Ontario, Canada. All 4 isolates were associated with cutaneous crusting lesions. Examination of selected samples by electron microscopy demonstrated th