Neuroprotective Effects of the Amylin Analog, Pramlintide, on Alzheimer’s Disease Are Associated with Oxidative Stress Regulation Mechanisms

Autor: Antonio Camins, Rachel Corrigan, Jeff Blair, Megan Mey, Sarah Patrick, Gemma Casadesus, John Grizzanti, Hyoung Gon Lee, Mercè Pallàs

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Administration of the recombinant analog of the pancreatic amyloid amylin, Pramlintide, has shown therapeutic benefits in aging and Alzheimer's disease (AD) models, both on cognition and amyloid-β (Aβ) pathology. However, the neuroprotective mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8893bed443c041e3adcd22356cece33
https://doi.org/10.3233/jad-180421

Contributors

Autor: Angela Marie Abbatecola, Ahmed Abdellatif, Shameemah Abrahams, Anne Almey, Sevilhan Artan, Hamdino Attia, Karina Ausin, Soraya Bardien, Martin Bareš, Minke Bekker, Amogh Belagodu, Antonello Bellomo, Olga A. Belova, Sebastián Beltrán-Castillo, Agata Białecka-De¸bek, Karina Henrique Binda, Daniel M. Blumberger, Mariangela Boccardi, Virginia Boccardi, Benjamin D. Boros, Luca Anna Bors, Alessandro Bortolami, Daniel C. Bowie, Francesca Bruno, Paulo Caramelli, G.P. Cardona-Gómez, Jonathan Carr, Paz Cartas-Cejudo, Gemma Casadesus, Grace M. Clements, Katelyn Cuttler, Antonio Daniele, Zafiris J. Daskalakis, Vittorio Dibello, Michelino Di Rosa, Velia D’Agata, Agata Grazia D’Amico, Andre du Toit, Mehrangiz Ebrahimi-Mameghani, B.J.L. Eggen, Okobi Ekpo, Franciska Erdő, Kirk I. Erickson, Ebru Erzurumluoglu Gokalp, Kurt A. Escobar, Jaime Eugenín, Monica Fabiani, Mahitab Farghali, Concetta Federico, Joaquín Fernández-Irigoyen, Federica Ferrari, Isidro Ferrer, Pavel Filip, Vanêssa Gomes Fraga, Mitsuhiro Furuse, Roberto Galvez, Samantha L. Gardener, Nicole J. Gervais, Gianluigi Giannelli, Laura Gil, Karina Braga Gomes, Andrea González-Morales, Stuart L. Graham, Gabriele Gratton, Antonio Greco, Andrey Grigoriev, Yian Gu, Lingyu Guan, Joshua M. Gulley, Vivek K. Gupta, Jeremy H. Herskowitz, Shozo Jinno, Lars Stiernman Jonasson, Mariona Jové, Shuo Kang, Michy P. Kelly, Ryuta Kinno, Maria G. Knyazeva, Joanne Koh, Marisa Koini, Yulia K. Komleva, Mercedes Lachén-Montes, Maddalena La Montagna, Anne Marlene Landau, Fulvio Lauretani, Ran Li, Yuandong Li, Xuan Li, Jennifer I. Lissemore, Ben Loos, Olga L. Lopatina, Madia Lozupone, Andrew G. MacLean, Tando Maduna, Marcello Maggio, Alireza Majdi, Hanani Abdul Manan, Raffaele Marfella, Grazia Maugeri, Naroa Mendizuri, Megan Mey, Kiyohito Mizutani, Claudio Molinari, Vera Morsanuto, Natalia Mota-Martorell, Sheeja Navakkode, Gina Nicoll, Kenjiro Ono, Demet Ozbabalik Adapinar, Reinald Pamplona, Francesco Panza, Tiffany A. Peterson, Irene Pradas, Victor R. Preedy, Stephanie R. Rainey-Smith, Caroline Cristiano Real, Catarina Rendeiro, Justin S. Rhodes, Georgia A.F. Rogerson, Sara Ruga, Salvatore Saccone, Saeed Sadigh-Eteghad, Vladimir V. Salmin, Alla B. Salmina, Mahzad Sanayei, Cristina Sanfilippo, Enrique Santamaría, Rodolfo Sardone, Heide Schatten, Davide Seripa, Federico Sesti, Ting Shen, Vincenzo Solfrizzi, Tuck Wah Soong, Anna Starnawska, Nicklas Heine Staunstrup, Chelsea Stillman, Valentina Sturiale, Yoshimi Takai, Dennis A. Turner, Francesca Uberti, Elnaz Vaghef-Mehrabany, Leila Vaghef-Mehrabany, Trisha A. VanDusseldorp, Roberto Federico Villa, J. Villamil-Ortiz, Rommy von Bernhardi, Ruikang K. Wang, Lauren Wengle, Yu-Chien Wu, Noorazrul Azmie Yahya, Jun Yamada, Wei Yang, Yuyi You, Ahmad Nazlim Yusoff, Jing Zhai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1708180369e2d2c0a4f369e659f8ea54
https://doi.org/10.1016/b978-0-12-817990-1.01002-7

The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

Autor: Shaneabbas Raza, Megan Meyer, Casey Goodyear, Kimberly D. P. Hammer, Bin Guo, Othman Ghribi

Publikováno v: Cancer Cell International, Vol 17, Iss 1, Pp 1-11 (2017)

Abstract Background For every six men, one will be diagnosed with prostate cancer (PCa) in their lifetime. Estrogen receptors (ERs) are known to play a role in prostate carcinogenesis. However, it is unclear whether the estrogenic effects are mediate

Externí odkaz: https://doaj.org/article/d03a89bcd8b04ce08f9502322cb503b7

Effect of broccoli sprouts on nasal response to live attenuated influenza virus in smokers: a randomized, double-blind study.

Autor: Terry L Noah, Hongtao Zhang, Haibo Zhou, Ellen Glista-Baker, Loretta Müller, Rebecca N Bauer, Megan Meyer, Paula C Murphy, Shannon Jones, Blanche Letang, Carole Robinette, Ilona Jaspers

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e98671 (2014)

Smokers have increased susceptibility and altered innate host defense responses to influenza virus infection. Broccoli sprouts are a source of the Nrf2 activating agentsulforaphane, and short term ingestion of broccoli sprout homogenates (BSH) has be

Externí odkaz: https://doaj.org/article/f4cfb3963af5441bac7b72c16d135e72

Exposure to ozone modulates human airway protease/antiprotease balance contributing to increased influenza A infection.

Autor: Matthew J Kesic, Megan Meyer, Rebecca Bauer, Ilona Jaspers

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35108 (2012)

Exposure to oxidant air pollution is associated with increased respiratory morbidities and susceptibility to infections. Ozone is a commonly encountered oxidant air pollutant, yet its effects on influenza infections in humans are not known. The great

Externí odkaz: https://doaj.org/article/0391df5bec924d3f8d17dacf9cba0572