Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Megan M. Rowland"'
Autor:
Rodrigo Borrega, Diana K. S. Nelson, Anatoliy P. Koval, Nell G. Bond, Megan L. Heinrich, Megan M. Rowland, Raju Lathigra, Duane J. Bush, Irina Aimukanova, Whitney N. Phinney, Sophia A. Koval, Andrew R. Hoffmann, Allison R. Smither, Antoinette R. Bell-Kareem, Lilia I. Melnik, Kaylynn J. Genemaras, Karissa Chao, Patricia Snarski, Alexandra B. Melton, Jaikin E. Harrell, Ashley A. Smira, Debra H. Elliott, Julie A. Rouelle, Gilberto Sabino-Santos, Arnaud C. Drouin, Mambu Momoh, John Demby Sandi, Augustine Goba, Robert J. Samuels, Lansana Kanneh, Michael Gbakie, Zoe L. Branco, Jeffrey G. Shaffer, John S. Schieffelin, James E. Robinson, Dahlene N. Fusco, Pardis C. Sabeti, Kristian G. Andersen, Donald S. Grant, Matthew L. Boisen, Luis M. Branco, Robert F. Garry
Publikováno v:
Viruses, Vol 13, Iss 11, p 2325 (2021)
Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger population could partly account for these differences, but pre-existing
Externí odkaz:
https://doaj.org/article/27d9109965114b0bbc7de5dfd8613f6a
Autor:
Jeffrey G. Shaffer, John S. Schieffelin, Mambu Momoh, Augustine Goba, Lansana Kanneh, Foday Alhasan, Michael Gbakie, Emily J. Engel, Nell G. Bond, Jessica N. Hartnett, Diana K. S. Nelson, Duane J. Bush, Matthew L. Boisen, Megan L. Heinrich, Megan M. Rowland, Luis M. Branco, Robert J. Samuels, Robert F. Garry, Donald S. Grant, the Viral Hemorrhagic Fever Consortium
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 586 (2021)
Lassa fever (LF) is a viral hemorrhagic disease found in Sub-Saharan Africa and is responsible for up to 300,000 cases and 5000 deaths annually. LF is highly endemic in Sierra Leone, particularly in its Eastern Province. Kenema Government Hospital (K
Externí odkaz:
https://doaj.org/article/602261afc2274b95985879eadc01bb62
Autor:
James E. Robinson, Kathryn M. Hastie, Robert W. Cross, Rachael E. Yenni, Deborah H. Elliott, Julie A. Rouelle, Chandrika B. Kannadka, Ashley A. Smira, Courtney E. Garry, Benjamin T. Bradley, Haini Yu, Jeffrey G. Shaffer, Matt L. Boisen, Jessica N. Hartnett, Michelle A. Zandonatti, Megan M. Rowland, Megan L. Heinrich, Luis Martínez-Sobrido, Benson Cheng, Juan C. de la Torre, Kristian G. Andersen, Augustine Goba, Mambu Momoh, Mohamed Fullah, Michael Gbakie, Lansana Kanneh, Veronica J. Koroma, Richard Fonnie, Simbirie C. Jalloh, Brima Kargbo, Mohamed A. Vandi, Momoh Gbetuwa, Odia Ikponmwosa, Danny A. Asogun, Peter O. Okokhere, Onikepe A. Follarin, John S. Schieffelin, Kelly R. Pitts, Joan B. Geisbert, Peter C. Kulakoski, Russell B. Wilson, Christian T. Happi, Pardis C. Sabeti, Sahr M. Gevao, S. Humarr Khan, Donald S. Grant, Thomas W. Geisbert, Erica Ollmann Saphire, Luis M. Branco, Robert F. Garry
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Lassa virus can cause haemorrhagic fever for which no specific treatment currently exists. Here the authors have cloned 113 monoclonal antibodies from the survivors of Lassa infection and show that the majority of neutralizing antibodies target a com
Externí odkaz:
https://doaj.org/article/d40aae7302c442638a735c72e28f07c6
Autor:
Haoyang Li, Tierra Buck, Michelle Zandonatti, Jieyun Yin, Alex Moon-Walker, Jingru Fang, Anatoliy Koval, Megan L. Heinrich, Megan M. Rowland, Ruben Diaz Avalos, Sharon L. Schendel, Diptiben Parekh, Dawid Zyla, Adrian Enriquez, Stephanie Harkins, Brian Sullivan, Victoria Smith, Onyeka Chukwudozie, Reika Watanabe, James E. Robinson, Robert F. Garry, Luis M. Branco, Kathryn M. Hastie, Erica Ollmann Saphire
Publikováno v:
Sci Transl Med
Developing potent therapeutics and effective vaccines are the ultimate goals in controlling infectious diseases. Lassa virus (LASV), the causative pathogen of Lassa fever (LF), infects hundreds of thousands annually, but effective antivirals or vacci
Autor:
Olusola A Ogunsanya, Francis Baimba, Johan Holst, Simji S. Gomerep, Robert F. Garry, Erica Ollmann Saphire, Peter O. Okokhere, Raju Lathigra, Viktoriya Borisevich, Diana K. S. Nelson, Luis M. Branco, Benevolence Ebo, Sylvanus Okogbenin, John S. Schieffelin, John Aiyepada, Mambu Momoh, Robert W. Cross, Megan L. Heinrich, Anatoliy P. Koval, Matthew L. Boisen, Thomas W. Geisbert, Augustine Goba, Megan M. Rowland, Andrew R. Hoffmann, Onikepe A. Folarin, E. E. Ella, John Demby Sandi, Christian T. Happi, Chinedu A Ugwu, lkponmwosa Odia, Johnson Etafo, Brandon J. Beddingfield, Macdonald Nonso Onyechi, Donald S. Grant, Jeffrey G. Shaffer, Rashidat Adeyemi, M. Aminu, Sophia A. Koval, Kathryn M. Hastie, Duane J. Bush, George O. Akpede, Philomena Eromon, Matthew Afam Eke, Danny Asogun, Irina Aimukanova, Testimony J. Olumade
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Lassa virus (LASV) is the causative agent of Lassa fever, an often-fatal hemorrhagic disease that is endemic in West Africa. Seven genetically distinct LASV lineages have been identified. As part of CEPI’s (Coalition for Epidemic Preparedness Innov
Autor:
Ekaete Alice Tobin, Matthew L. Boisen, Meike Pahlmann, Chris Aire, Diana K. S. Nelson, John S. Schieffelin, Adeyemi T. Kayode, Luis M. Branco, Solomon Ehikhametalor, Onikepe A. Folarin, Patience Akhilomen, Jacqueline Agbukor, Danny Asogun, Donatus I Adomeh, Ikponmwosa Odia, Grace Okonofua, John Aiyepada, Katherine J. Siddle, Blessing Osiemi, Augustine Goba, Ephraim Ogbaini-Emovan, Megan L. Heinrich, Kayla G. Barnes, Peter O. Okokhere, John Demby Sandi, Megan M. Rowland, Philomena Eromon, Pardis C. Sabeti, Robert F. Garry, Ekene B. Muoebonam, Samar B. Mehta, Eghosa Uyigue, Christian T. Happi, Michael Airende, Stephan Günther, Sophie Duraffour, Lisa Oestereich, Sylvanus Okogbenin, Omigie Omoregie, Donald S. Grant, Duane J. Bush, George O. Akpede, Mambu Momoh, Wiebke Böhm
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Lassa virus (LASV) is the causative agent of Lassa fever (LF), an often-fatal hemorrhagic disease. LF is endemic in Nigeria, Sierra Leone and other West African countries. Diagnosis of LASV infection is challenged by the genetic diversity of the viru
Autor:
Augustine Goba, John Demby Sandi, Luis M. Branco, Megan L. Heinrich, Sophia A. Koval, Mambu Momoh, Karissa Chao, Patricia Snarski, Duane J. Bush, Andrew R. Hoffmann, Alexandra Melton, Nell G. Bond, Antoinette R. Bell-Kareem, Irina Aimukanova, Robert J. Samuels, Matthew L. Boisen, Rodrigo Borrega, Jaikin E Harrell, Lansana Kanneh, Anatoliy P. Koval, Megan M. Rowland, Whitney N. Phinney, Zoe L. Branco, Robert F. Garry, Pardis C. Sabeti, Debra Elliott, Diana K. S. Nelson, Kristian G. Andersen, Dahlene N. Fusco, James E. Robinson, Kaylynn J. Genemaras, Lilia I. Melnik, Raju Lathigra, Jeffrey G. Shaffer, Michael Gbakie, Julie A. Rouelle, Ashley A. Smira, Allison R. Smither, John S. Schieffelin, Gilberto Sabino-Santos, Don Grant, Arnaud Drouin
Publikováno v:
Viruses, Vol 13, Iss 2325, p 2325 (2021)
Viruses
Viruses; Volume 13; Issue 11; Pages: 2325
Viruses
Viruses; Volume 13; Issue 11; Pages: 2325
Many countries in sub-Saharan Africa have experienced lower COVID-19 caseloads and fewer deaths than countries in other regions worldwide. Under-reporting of cases and a younger population could partly account for these differences, but pre-existing
Autor:
Karla A. Fenton, Megan L. Heinrich, Donald S. Grant, Robert F. Garry, Mathew L Boisen, Mohamed Fullah, Viktoriya Borisevich, Mambu Momoh, Sheik Humarr Khan, Luis M. Branco, Robert W. Cross, Megan M. Rowland, Thomas W. Geisbert, Chad E. Mire, Daniel J. Deer, James E. Robinson, Augustine Goba, Krystle N. Agans, Joan B. Geisbert
Publikováno v:
Nature Medicine. 23:1146-1149
There are no approved treatments for Lassa fever, which is endemic to the same regions of West Africa that were recently devastated by Ebola. Here we show that a combination of human monoclonal antibodies that cross-react with the glycoproteins of al
Autor:
Erica Ollmann Saphire, Megan L. Heinrich, Michelle Zandonatti, Robert F. Garry, James E. Robinson, Megan M. Rowland, Lara M. Kleinfelter, Kartik Chandran, Luis M. Branco, Kathryn M. Hastie
Publikováno v:
Science. 356:923-928
The arenavirus Lassa causes severe hemorrhagic fever and a significant disease burden in West Africa every year. The glycoprotein, GPC, is the sole antigen expressed on the viral surface and the critical target for antibody-mediated neutralization. H
Autor:
Megan L. Heinrich, Michelle Zandonatti, Kathryn M. Hastie, Thomas W. Geisbert, Erica Ollmann Saphire, James E. Robinson, Robert W. Cross, Robert F. Garry, Megan M. Rowland, Stephanie Harkins, Luis M. Branco, Anatoliy P. Koval
Publikováno v:
Cell
Summary Lassa virus (LASV) causes hemorrhagic fever and is endemic in West Africa. Protective antibody responses primarily target the LASV surface glycoprotein (GPC), and GPC-B competition group antibodies often show potent neutralizing activity in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e636320bc68f46ac305da4f7786ff9f5
https://europepmc.org/articles/PMC6814208/
https://europepmc.org/articles/PMC6814208/