Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos

Autor: Jeffrey C. Medley, Megan M. Kabara, Michael D. Stubenvoll, Lauren E. DeMeyer, Mi Hye Song

Publikováno v: Biology Open, Vol 6, Iss 1, Pp 17-28 (2017)

Centrosomes are the primary microtubule-organizing centers that orchestrate microtubule dynamics during the cell cycle. The correct number of centrosomes is pivotal for establishing bipolar mitotic spindles that ensure accurate segregation of chromos

Externí odkaz: https://doaj.org/article/bbe7a0ce7f9e45caaf7b970ad99e12fe

APC/C

Autor: Jeffrey C, Medley, Lauren E, DeMeyer, Megan M, Kabara, Mi Hye, Song

Publikováno v: G3: Genes|Genomes|Genetics

As the primary microtubule-organizing center, centrosomes play a key role in establishing mitotic bipolar spindles that secure correct transmission of genomic content. For the fidelity of cell division, centrosome number must be strictly controlled b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::217047f9dd13eddf12a11d79cfae0478
https://pubmed.ncbi.nlm.nih.gov/29030390

Site-specific phosphorylation of ZYG-1 regulates ZYG-1 stability and centrosome number.

Autor: Medley JC; Department of Biological Sciences, Oakland University, Rochester, MI, USA., Yim RN; Department of Biological Sciences, Oakland University, Rochester, MI, USA., DiPanni J; Department of Biological Sciences, Oakland University, Rochester, MI, USA., Sebou B; Department of Biological Sciences, Oakland University, Rochester, MI, USA., Shaffou B; Department of Biological Sciences, Oakland University, Rochester, MI, USA., Cramer E; Department of Chemistry, Oakland University, Rochester, MI, USA., Wu C; Department of Chemistry, Oakland University, Rochester, MI, USA., Kabara M; Department of Biological Sciences, Oakland University, Rochester, MI, USA.; University of Connecticut School of Medicine, Office of Graduate Medical Education, Farmington, CT, USA., Song MH; Department of Biological Sciences, Oakland University, Rochester, MI, USA.

Publikováno v: IScience [iScience] 2023 Nov 08; Vol. 26 (12), pp. 108410. Date of Electronic Publication: 2023 Nov 08 (Print Publication: 2023).