Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Megan M O'Meara"'
Autor:
Ronald A. Lubet, Piper M. Treuting, Megan M. O'Meara, Denise L. Cecil, Kyong Hwa Park, Vy Phan- Lai, Daniel R. Herendeen, Ekram Gad, Mary L. Disis
A multiantigen multipeptide vaccine, targeting proteins expressed in preinvasive breast lesions, can stimulate type I CD4+ T cells which have been shown to be deficient in both patients with breast cancer and mice that develop mammary tumors. Transge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a25697516ad6dd105b032fe2b08fda
https://doi.org/10.1158/1940-6207.c.6544872.v1
https://doi.org/10.1158/1940-6207.c.6544872.v1
Autor:
Ronald A. Lubet, Piper M. Treuting, Megan M. O'Meara, Denise L. Cecil, Kyong Hwa Park, Vy Phan- Lai, Daniel R. Herendeen, Ekram Gad, Mary L. Disis
PDF file - 3266K, Supplemental Figure 1. Protein expression of vaccine component antigens in preinvasive lesions derived from TgMMTV-neu mice. Supplemental Figure 2. Multi-antigen peptide vaccine controls tumor growth in a TgC3(I)-Tag implant model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37cf1f7bf4273e4539334fe685ee73ac
https://doi.org/10.1158/1940-6207.22525707
https://doi.org/10.1158/1940-6207.22525707
Autor:
Mary L. Disis, Lauren Rastetter, Daniel Herendeen, Yushe Dang, Ekram Gad, Benjamin C. Curtis, Megan M. O'Meara, Meredith Slota, Denise L. Cecil
Purpose: Triple-negative breast cancer (TNBC) represents a cancer stem cell–enriched phenotype. Hypoxia-inducible factor-1α (HIF-1α) induces the expression of proteins associated with stemness and is highly upregulated in TNBC. We questioned whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61dd7c6cb23bf6e4c37d558e2d3ff0f9
https://doi.org/10.1158/1078-0432.c.6525398.v1
https://doi.org/10.1158/1078-0432.c.6525398.v1
Autor:
Mary L. Disis, Lauren Rastetter, Daniel Herendeen, Yushe Dang, Ekram Gad, Benjamin C. Curtis, Megan M. O'Meara, Meredith Slota, Denise L. Cecil
Supplementary Table 1. Th1/Th2 for eleven epitopes derived from the HIF-1α protein; Supplementary Table 2. Number of tumorigenic implants in the Sca-1positive or Sca-1negative Population; Supplementary Table 3. Complete blood count (median and range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9757e6ee7211e970c11cfd1d8e6c9336
https://doi.org/10.1158/1078-0432.22463420
https://doi.org/10.1158/1078-0432.22463420
Autor:
Stefan Faderl, Dale L. Bixby, Megan M. O'Meara, Phoenix A. Ho, Moshe Yair Levy, Harry P. Erba, Anjali S. Advani, Anthony S. Stein, Jenna L Voellinger, Farhad Ravandi, Roland B. Walter, Jeffrey E. Lancet, Amir T. Fathi, Daniel J. DeAngelo, Eytan M. Stein, Tibor Kovacsovics, Anand Jillella
Treatment of acute myeloid leukemia (AML) among the elderly is challenging because of intolerance of intensive therapy and therapy-resistant biology. Hypomethylating agents (HMAs) are commonly used, with suboptimal outcomes. Vadastuximab talirine is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84751e56edf80512a87018fa74e9a43
https://europepmc.org/articles/PMC6265631/
https://europepmc.org/articles/PMC6265631/
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Introduction: Vascular progenitor cells (VPCs) represent the repair and regenerative potential of vasculature. VPC function has been found severely impaired in diabetes with mechanisms not fully understood. We previously demonstrated that inositol re
Autor:
Stefan Faderl, Amir T. Fathi, Megan M. O'Meara, Daniel J. DeAngelo, Charles Biddle-Snead, Dale L. Bixby, Eytan M. Stein, Roland B. Walter, Phoenix A. Ho, Jeffrey E. Lancet, Anjali S. Advani, Anthony S. Stein, Anand Jillella, Farhad Ravandi, Harry P. Erba, Tibor Kovacsovics, Baiteng Zhao
Vadastuximab talirine (SGN-CD33A, 33A) is an antibody-drug conjugate consisting of pyrrolobenzodiazepine dimers linked to a monoclonal antibody targeting CD33, which is expressed in the majority of acute myeloid leukemia (AML) patients. This phase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c272400f99585e3bd9d5e0f0afe196ba
https://europepmc.org/articles/PMC5813721/
https://europepmc.org/articles/PMC5813721/
Autor:
Jonathan W. Friedberg, Jasmine Zain, Jeffrey Matous, Andrei R. Shustov, Nancy L. Bartlett, Robert T. Chen, Michelle A. Fanale, Andres Forero-Torres, Megan M. O'Meara, Scott E. Smith, Anas Younes, Ajay K. Gopal
Publikováno v:
Leukemia & Lymphoma. 55:2328-2334
Older adults constitute a significant proportion of the cancer population, but are underrepresented in clinical trials. We conducted a retrospective analysis of the safety and efficacy of brentuximab vedotin in adults ≥ 60 years with relapsed CD30-
Autor:
Don M. Benson, Megan M. O'Meara, Luke P. Akard, Ben Exter, Jessica Sachs, Tooba A. Cheema, Ann Ranger, Parameswaran Hari, Django Sussman, Iga Sienczylo, Houston Holmes
Publikováno v:
Blood. 132:1997-1997
Background: B cell maturation antigen (BCMA) has recently emerged as a promising candidate antigen for therapeutic targeting in multiple myeloma (MM), with several targeted agents in clinical studies including antibody-drug conjugates and bispecific