Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Megan Lewicki"'
Publikováno v:
Journal of Proteomics. 118:39-48
The small ubiquitin-related modifier (SUMO) “stress response” (SSR) is a poorly understood evolutionarily conserved phenomenon in which steady-state SUMO conjugate levels are dramatically increased in response to environmental stresses. Here we c
Autor:
Christopher J. Patterson, Megan Lewicki, Leukothea Ioakimidis, Tabatha N. Offutt-Powell, Robert Manning, Sander Greenland, Christina Hanzis, Steven P. Treon, Rohit P. Ojha, Philip Brodsky, Christina K. Tripsas, Zachary R. Hunter, Patricia Sheehy, Karan P. Singh
Publikováno v:
Cancer Epidemiology. 36:294-297
Background Little is known about the epidemiology and etiology of Waldenstrom macroglobulinemia (WM). Despite several studies of the relation between family history and B-cell disorders and WM, family history of non-hematologic cancers has not been s
Autor:
Patricia Sheehy, Steven P. Treon, Christina K. Tripsas, Megan Lewicki, Christopher J. Patterson, Zachary R. Hunter, Rohit P. Ojha, Robert Manning, Leukothea Ioakimidis, Christina Hanzis, Philip Brodsky
Publikováno v:
Clinical lymphoma, myelomaleukemia. 11(1)
We examined the incidence of other malignancies in 924 Waldenstrom's Macroglobulinemia (WM) patients and their kin. A total of 225 (24.3%) patients had ≥1 additional malignancy, with 63% predating the WM diagnosis. The most common gender-adjusted m
Autor:
Lian Xu, C. A. Hanzis, Ping Gong, Bryan Ciccarelli, Leukothea Ioakimidis, Steven P. Treon, Hsuiyi Tseng, Christopher J. Patterson, Xia Liu, Jenny Sun, Massimo Morra, Megan Lewicki, Robert Manning, Zachary R. Hunter, Guang Yang, Patricia Sheehy, Yangsheng Zhou
Background Hypogammaglobulinemia is common in Waldenstrom’s macroglobulinemia. The etiology of this finding remains unclear, but it has been speculated to be based on tumor-induced suppression of the ‘uninvolved’ immunoglobulin productionDesign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59373cf5a74cb807ba75b5bdde869949
https://europepmc.org/articles/PMC2833078/
https://europepmc.org/articles/PMC2833078/
Autor:
Philip Brodsky, Christina Hanzis, Leukothea Ioakimidis, Megan Lewicki, Robert Manning, Christina K. Tripsas, Patricia Sheehy, Zachary R. Hunter, Christopher J. Patterson, Steven P. Treon
Publikováno v:
Blood. 116:4159-4159
Abstract 4159 Waldenstrom's macroglobulinemia (WM) is a B-cell malignancy characterized as an IgM secreting lymphoplasmacytic lymphoma. Familial predisposition is common in WM. Studies to date by us and others have revealed three identifiable clinica
Autor:
Jingrui Jiang, Steven P. Treon, Yangsheng Zhou, Megan Lewicki, Robert Manning, Hsiuyi Tseng, Guang Yang, Christopher J. Patterson, Yang Cao, Jenny Sun, Christina Hanzis, Zachary R. Hunter, Xia Liu, Lian Xu, Philip Brodsky
Publikováno v:
Blood. 116:1912-1912
Abstract 1912 Background: Waldenstrom's Macroglobulinemia (WM) is a rare low grade non-Hodgkin's lymphoma characterized by the accumulation of IgM secreting lymphoplasmacytic cells in (LPC) the bone marrow, an elevated serum IgM, and frequently accom
Autor:
Christina Hanzis, Bryan Ciccarelli, Megan Lewicki, Philip Brodsky, Robert Manning, Steven P. Treon, Patricia Sheehy, Zachary R. Hunter, Christopher J. Patterson
Publikováno v:
Blood. 116:1911-1911
Abstract 1911 Waldenstrom's macroglobulinemia (WM) is a B-cell lymphoplasmacytic disorder characterized by elevated clonal IgM secretion and bone marrow infiltration. Dysregulation of plasma cytokines and chemokines have been described in related mal
Autor:
Christopher J. Patterson, Jenny Sun, Yang Cao, Xia Liu, Zachary R. Hunter, Hsiuyi Tseng, Bryan Ciccarelli, Patricia Sheehy, Yangsheng Zhou, Lian Xu, Megan Lewicki, Steven P. Treon, Thea Ioakimidis, Robert Manning, Ping Gong, Christina Hanzis, Guang Yang
Publikováno v:
Blood. 114:761-761
Abstract 761 Introduction: Rituximab is an important treatment option in Waldenstrom's Macroglobulinemia (WM). We and others have previously reported a paradoxical flare in serum IgM levels following rituximab administration which can occur within ho
Autor:
Hsiuyi Tseng, Thea Ioakimidis, Yang Cao, Guang Yang, Patricia Sheehy, Yangsheng Zhou, Xia Liu, Christopher J. Patterson, Ping Gong, Jenny Sun, Bryan Ciccarelli, Steven P. Treon, Lian Xu, Zachary R. Hunter, Christina Hanzis, Megan Lewicki, Robert Manning
Publikováno v:
Blood. 114:3736-3736
Abstract 3736 Poster Board III-672 Introduction Waldenstrom's macroglobulinemia (WM) is a lymphoplasmacytic lymphoma characterized by overproduction of a monoclonal IgM paraprotein which can produce morbidity including hyperviscosity, as well as auto
Autor:
Hsiuyi Tseng, Megan Lewicki, Robert Manning, Guang Yang, Xia Liu, Evdoxia Hatjiharissi, Yangsheng Zhou, Thea Ioakimidis, Ping Gong, Zachary R. Hunter, Christopher J. Patterson, Lian Xu, Jenny Sun, Christina Hanzis, Steven P. Treon, Bryan Ciccarelli, Yang Cao
Publikováno v:
Blood. 114:2954-2954
Abstract 2954 Poster Board II-930 The deleted in liver cancer-1 (DLC-1) gene encodes a Rho GTPase activating protein (RhoGAP) with potential tumor-suppressor activity. Hypermethylation in the DLC-1 promoter is an aberrant epigenetic modification asso