Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Megan Larmore"'
Publikováno v:
eLife, Vol 13 (2024)
Ion channels are biological transistors that control ionic flux across cell membranes to regulate electrical transmission and signal transduction. They are found in all biological membranes and their conductive state kinetics are frequently disrupted
Externí odkaz:
https://doaj.org/article/a209b4f45c1b4bcf8b64d63e4fd03c4e
Publikováno v:
Annu Rev Physiol
Polycystin subunits can form hetero- and homotetrameric ion channels in the membranes of various compartments of the cell. Homotetrameric polycystin channels are voltage- and calcium-modulated, whereas heterotetrameric versions are proposed to be lig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e3ea71f7e1b4b6a0c2ede747fed375
https://doi.org/10.1146/annurev-physiol-031522-084334
https://doi.org/10.1146/annurev-physiol-031522-084334
Autor:
Leo CT Ng, Brandon J Harris, Megan Larmore, My C Ta, Thuy N Vien, Valerie L Tokars, Vladimir Yarov‐Yarovoy, Paul G DeCaen
Publikováno v:
EMBO reports.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::172e9c97826c3fd5ecaed341a9c4ced2
https://doi.org/10.15252/embr.202356783
https://doi.org/10.15252/embr.202356783
Publikováno v:
Biophysical Journal. 122:395a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97bfe814d7a39a417d7e72cf14403ac6
https://doi.org/10.1016/j.bpj.2022.11.2156
https://doi.org/10.1016/j.bpj.2022.11.2156
Autor:
Megan M. McCollum, Megan Larmore, Shingo Ishihara, Leo C.T. Ng, Louise F. Kimura, Eduardo Guadarrama, My C. Ta, Thuy N. Vien, Grant B. Frost, Karl A. Scheidt, Rachel E. Miller, Paul G. DeCaen
Publikováno v:
Cell Rep
Voltage-gated sodium channels (Na(V)) in nociceptive neurons initiate action potentials required for transmission of aberrant painful stimuli observed in osteoarthritis (OA). Targeting these Na(V) subtypes with drugs to produce analgesic effects for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc420d0117415386d44a4713aaa2e597
https://pubmed.ncbi.nlm.nih.gov/36001977
https://pubmed.ncbi.nlm.nih.gov/36001977
Autor:
Taha Al-Shaikhly, Ryan C. Murphy, Andrew Parker, Ying Lai, Matthew C. Altman, Megan Larmore, William A. Altemeier, Charles W. Frevert, Jason S. Debley, Adrian M. Piliponsky, Steven F. Ziegler, Michael C. Peters, Teal S. Hallstrand
Publikováno v:
The European respiratory journal. 60(2)
BackgroundEosinophils are implicated as effector cells in asthma, but the functional implications of the precise location of eosinophils in the airway wall is poorly understood. We aimed to quantify eosinophils in the different compartments of the ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52568ff10e2f3b42510cbf9418f3f803
https://pubmed.ncbi.nlm.nih.gov/35027395
https://pubmed.ncbi.nlm.nih.gov/35027395
Autor:
Bonnie A. Wallace, Altin Sula, David Hollingworth, Megan Larmore, Leo C. T. Ng, Paul G. DeCaen
Publikováno v:
Molecular Cell
Summary Voltage-gated sodium channels are targets for many analgesic and antiepileptic drugs whose therapeutic mechanisms and binding sites have been well characterized. We describe the identification of a previously unidentified receptor site within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41003d7eace3da32c382f528142447f
https://eprints.bbk.ac.uk/id/eprint/42793/1/42793.pdf
https://eprints.bbk.ac.uk/id/eprint/42793/1/42793.pdf
