Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Megan L. Schumacher"'
Autor:
Kayla A. Simanek, Megan L. Schumacher, Caleb P. Mallery, Stella Shen, Lingyun Li, Jon E. Paczkowski
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Quorum sensing is a mechanism of bacterial communication that controls virulence gene expression. Pseudomonas aeruginosa regulates virulence via two synthase/transcription factor receptor pairs: LasI/R and RhlI/R. LasR is considered the mast
Externí odkaz:
https://doaj.org/article/0eeec8cb17924dcd9ad5c9f97ad694a7
Autor:
Jacob W. Adelman, Suzette Rosas-Rogers, Megan L. Schumacher, Rebekah L. Mokry, Scott S. Terhune, Allison D. Ebert
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTHuman cytomegalovirus (HCMV) is a highly prevalent viral pathogen that typically presents asymptomatically in healthy individuals despite lifelong latency. However, in 10%–15% of congenital cases, this beta-herpesvirus demonstrates direct e
Externí odkaz:
https://doaj.org/article/87eb1df001c54c70b2eed88e8b4f6be9
Autor:
Benjamin S. O’Brien, Rebekah L. Mokry, Megan L. Schumacher, Kirthi Pulakanti, Sridhar Rao, Scott S. Terhune, Allison D. Ebert
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104098- (2022)
Summary: Human cytomegalovirus (HCMV) is a betaherpesvirus that can cause severe birth defects including vision and hearing loss, microcephaly, and seizures. Currently, no approved treatment options exist for in utero infections. Here, we aimed to de
Externí odkaz:
https://doaj.org/article/b804a6a5650942949bb467eb6eb46ff6
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Nitric oxide is a versatile and critical effector molecule that can modulate many cellular functions. Although recognized as a regulator of infections, the inhibitory mechanism of nitric oxide against human cytomegalovirus (HCMV) replication
Externí odkaz:
https://doaj.org/article/eb9b878d299448939c1aa131b0a70dc1
Autor:
Benjamin S. O’Brien, Rebekah L. Mokry, Megan L. Schumacher, Suzette Rosas, Scott S. Terhune, Allison D. Ebert
Human cytomegalovirus (HCMV) is a beta herpesvirus that causes severe congenital birth defects including microcephaly, vision loss, and hearing loss. Infection of cerebral organoids with HCMV causes significant downregulation of genes involved in cri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fac3769ac7f03076cf44b6ac802184c
https://doi.org/10.1101/2023.03.02.530870
https://doi.org/10.1101/2023.03.02.530870
Autor:
Rebekah L. Mokry, Benjamin S. O’Brien, Jacob W. Adelman, Suzette Rosas, Megan L. Schumacher, Allison D. Ebert, Scott S. Terhune
Publikováno v:
J Virol
Human cytomegalovirus (HCMV) is a prevalent betaherpesvirus that is asymptomatic in healthy individuals but can cause serious disease in immunocompromised patients. HCMV is also the leading cause of virus-mediated birth defects. Many of these defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed645e1002a0cd004271e832ed405ea3
https://europepmc.org/articles/PMC9327702/
https://europepmc.org/articles/PMC9327702/
Autor:
Sridhar Rao, Benjamin S. O’Brien, Megan L. Schumacher, Kirthi Pulakanti, Rebekah L. Mokry, Allison D. Ebert, Scott S. Terhune
Human cytomegalovirus (HCMV) is a beta herpesvirus that, upon congenital infection, can cause severe birth defects including vision and hearing loss, microcephaly, and seizures. Currently, no approved treatment options exist for in utero infections.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::027fb41fbed70586c4cc72aca64f7fc4
https://doi.org/10.1101/2021.08.01.454651
https://doi.org/10.1101/2021.08.01.454651
Autor:
Benjamin S. O’Brien, Rebekah L. Mokry, Megan L. Schumacher, Kirthi Pulakanti, Sridhar Rao, Scott S. Terhune, Allison D. Ebert
Publikováno v:
SSRN Electronic Journal.
Human cytomegalovirus (HCMV) is a betaherpesvirus that can cause severe birth defects including vision and hearing loss, microcephaly, and seizures. Currently, no approved treatment options exist for