Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Megan L. O'Brien"'
Autor:
Andrew D. Fesnak, Simon F. Lacey, Jennifer Brogdon, Joseph A. Fraietta, Noelle V. Frey, Bruce L. Levine, Boris Engels, David L. Porter, Saar Gill, Alexander E. Perl, Amy Marshall, Megan L. O'Brien, Selina M. Luger, Shannon R. McCurdy, Carl H. June, Julie S. Barber-Rotenberg, Alison W. Loren, Keith W. Pratz, Theresa Schanne, Mary Ellen Martin, Elizabeth O. Hexner, Marco Ruella, Wei-Ting Hwang
Publikováno v:
Blood. 138:469-469
Background: Genetically modified T cells expressing an anti-CD19 murine chimeric antigen receptor (CAR) result in response rates of up to 90% in patients with relapsed or refractory (r/r) B cell acute lymphoblastic leukemia (ALL). Durable remissions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a75f785c92acfeea151ba412fed32c
https://doi.org/10.1182/blood-2021-153955
https://doi.org/10.1182/blood-2021-153955
Autor:
Julie Silvestri, Sarah Radwandi, Michael C. Rabel, Mathew Hannan, Megan L. O’Brien, Sheriff Dosoumu
Publikováno v:
Medicine & Science in Sports & Exercise. 49:463-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b66b806d8fa9ca653d1b56f400019afa
https://doi.org/10.1249/01.mss.0000518159.74841.50
https://doi.org/10.1249/01.mss.0000518159.74841.50
Autor:
Saar Gill, Stephen J. Schuster, Noelle V. Frey, Simon F. Lacey, Randi Isaacs, David L. Porter, Wei-Ting Hwang, Megan Davis, Elizabeth O. Hexner, Anne Lamontagne, John C. Byrd, Anthony R. Mato, Megan L. O'Brien, J. Joseph Melenhorst, Vanessa Vides, Carl H. June, Edward Pequignot, Whitney L. Gladney, Susan Metzger, Don L. Siegel
Publikováno v:
Blood. 132:298-298
Background Immunotherapy with anti-CD19 CART cells (CART19) induces complete remission (CR) in the minority of patients with CLL; however, these CRs tend to be durable (Porter Sci Tr Med 2015). Based on preclinical evidence of synergy, we combined an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af3cbce4b7c886e7bb4b1793e04c7185
https://doi.org/10.1182/blood-2018-99-115418
https://doi.org/10.1182/blood-2018-99-115418
Autor:
Nicholas J. Dormans, Kenro Kusumi, Kathleen M. Loomes, Matthew J. Ryan, Hyun-Duck Nah, Dorian M. Gonzalez, Mizuho S. Mimoto, Eric F. Rappaport, Michelle Segalov, Stacey A. Stevens, Alyssa A. Schaffer, Megan L. O'Brien, Joshua D. Gibson, Sally L. Dunwoodie, William F. Sewell, Stephen C. Pratt
Publikováno v:
Developmental Dynamics. 236:2943-2951
Mutations in the Notch1 receptor and delta-like 3 (Dll3) ligand cause global disruptions in axial segmental patterning. Genetic interactions between members of the notch pathway have previously been shown to cause patterning defects not observed in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfa0ba0d0d81bc32906edd28238220e
https://doi.org/10.1002/dvdy.21296
https://doi.org/10.1002/dvdy.21296
Autor:
John P. Dormans, Frederick S. Kaplan, Alyssa A. Schaffer, Michael R. Tracy, Eileen M. Shore, Richard M. Harland, Megan L. O'Brien, Kenro Kusumi
Publikováno v:
Spine. 30:1379-1385
STUDY DESIGN A radiographic analysis of the cervical spine of 70 patients diagnosed with fibrodysplasia ossificans progressiva (FOP) and 33 diagnosed with Klippel-Feil (KF) syndrome was conducted. OBJECTIVES The objectives of this study were to descr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbeb3ba6b6abd9cae954186cc95cc80
https://doi.org/10.1097/01.brs.0000166619.22832.2c
https://doi.org/10.1097/01.brs.0000166619.22832.2c
Autor:
Megan L. O'Brien, Melissa K. Maisenbacher, Elaine H. Zackai, Kenro Kusumi, John P. Dormans, Michael R. Tracy, Alyssa A. Schaffer, Bülent Erol, Ji Soo Han
Publikováno v:
Human Genetics. 116:416-419
The etiology of congenital scoliosis is largely unknown. The severe vertebral disorder, spondylocostal dysostosis type 1, is associated with a homozygous delta-like 3 (DLL3) mutation. Scoliosis has been observed in a heterozygous DLL3 carrier, raisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519549a9271218eefbd04611738061f1
https://doi.org/10.1007/s00439-005-1253-8
https://doi.org/10.1007/s00439-005-1253-8
Autor:
Kenro Kusumi, Elaine H. Zackai, Bülent Erol, John P. Dormans, Peter D. Turnpenny, Michael R. Tracy, Megan L. O'Brien, Melissa K. Maisenbacher
Publikováno v:
Journal of Pediatric Orthopaedics. 24:674-682
The developmental and genetic etiology of most congenital vertebral malformation disorders remains unknown. The objective of this study was to evaluate and classify congenital vertebral defect cases into groupings based on developmental etiology for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d6b2dea34efdb079d5c164b365812b
https://doi.org/10.1097/01241398-200411000-00015
https://doi.org/10.1097/01241398-200411000-00015
Publikováno v:
Advances in experimental medicine and biology. 638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4e313ddd4752ced17608b03b688085a
https://pubmed.ncbi.nlm.nih.gov/21038775
https://pubmed.ncbi.nlm.nih.gov/21038775
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387096056
The mouse was one of the first model organisms used in genetic analysis, beginning in 1902 with the studies of inheritance carried out by William E. Castle, Director of the Bussey Institute at Harvard1. The first mutations identified derived from mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4357a0ccdd4e1966f03dc3c09daeb65c
https://doi.org/10.1007/978-0-387-09606-3_8
https://doi.org/10.1007/978-0-387-09606-3_8
Autor:
James M. Ryan, Allanceson J. Smith, Kathleen M. Loomes, William F. Sewell, Megan L. O'Brien, Eric F. Rappaport, Dorian M. Gonzalez, Stacey A. Stevens
Publikováno v:
Developmental Biology. 306(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cb02a82bc4049e6c5b73d7d4ab81c6