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pro vyhledávání: '"Megan L. Linscott"'
Publikováno v:
Non-Coding RNA, Vol 9, Iss 6, p 74 (2023)
Aging in women is accompanied by a dramatic change in circulating sex steroid hormones. Specifically, the primary circulating estrogen, 17β-estradiol (E2), is nearly undetectable in post-menopausal women. This decline is associated with a variety of
Externí odkaz:
https://doaj.org/article/fa87cd9c16a04159becb2734363afd83
Publikováno v:
Non-Coding RNA, Vol 7, Iss 3, p 53 (2021)
Clinical studies demonstrated that the ovarian hormone 17β-estradiol (E2) is neuroprotective within a narrow window of time following menopause, suggesting that there is a biological switch in E2 action that is temporally dependent. However, the mol
Externí odkaz:
https://doaj.org/article/2d4490e3d8004b77af45baeb3eac1d7b
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
Over the last few years, numerous studies solidified the hypothesis that fibroblast growth factor (FGF) signaling regulates neuroendocrine progenitor cell proliferation, fate-specification, and cell survival, and therefore is critical for the regulat
Externí odkaz:
https://doaj.org/article/c65bf9bf337a4cc4a59677f53521e247
Autor:
Megan L. Linscott, Wilson CJ Chung
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 4 (2016)
Fibroblast growth factor 8 (FGF8) is a potent morphogen that regulates the embryonic development of hypothalamic neuroendocrine cells. Indeed, using Fgf8 hypomorphic mice, we showed that reduced Fgf8 mRNA expression completely eliminated the presence
Externí odkaz:
https://doaj.org/article/805fdf333a8041e989a5817c5a273b2a
Autor:
Wilson C. J. Chung, Megan L. Linscott
Publikováno v:
Journal of Neuroendocrinology. 32
Mammalian reproductive success depends on gonadotrophin-releasing hormone (GnRH) neurones to stimulate gonadotrophin secretion from the anterior pituitary and activate gonadal steroidogenesis and gametogenesis. Genetic screening studies in patients d
Autor:
Megan L. Linscott, Wilson C. J. Chung
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220530 (2019)
PLoS ONE
PLoS ONE
Fibroblast growth factor 8 (FGF8) is a potent morphogen that regulates the ontogenesis of gonadotropin-releasing hormone (GnRH) neurons, which control the hypothalamus-pituitary-gonadal (HPG) axis, and therefore reproductive success. Indeed, FGF8 and
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 7 (2016)
Frontiers in Endocrinology, Vol 7 (2016)
Over the last few years, numerous studies solidified the hypothesis that fibroblast growth factor (FGF) signaling regulates neuroendocrine progenitor cell proliferation, fate-specification, and cell survival, and therefore is critical for the regulat
Autor:
Megan L. Linscott, Wilson C. J. Chung, Erica L. Stevenson, Karla M. Rodriguez, Courtney E. Stewart
Publikováno v:
Behavioral and Brain Functions : BBF
Background Fibroblast growth factors (FGFs) are crucial signaling molecules that direct the development of the vertebrate brain. FGF8 gene signaling in particular, may be important for the development of the hypothalamus–pituitary–adrenal (HPA)-a