Researching COVID to enhance recovery (RECOVER) tissue pathology study protocol: Rationale, objectives, and design.

Autor: Andrea B Troxel, Marie-Abele C Bind, Thomas J Flotte, Carlos Cordon-Cardo, Lauren A Decker, Aloke V Finn, Robert F Padera, R Ross Reichard, James R Stone, Natalie L Adolphi, Faye Victoria C Casimero, John F Crary, Jamie Elifritz, Arline Faustin, Saikat Kumar B Ghosh, Amanda Krausert, Maria Martinez-Lage, Jonathan Melamed, Roger A Mitchell, Barbara A Sampson, Alan C Seifert, Aylin Simsir, Cheryle Adams, Stephanie Haasnoot, Stephanie Hafner, Michelle A Siciliano, Brittany B Vallejos, Phoebe Del Boccio, Michelle F Lamendola-Essel, Chloe E Young, Deepshikha Kewlani, Precious A Akinbo, Brendan Parent, Alicia Chung, Teresa C Cato, Praveen C Mudumbi, Shari Esquenazi-Karonika, Marion J Wood, James Chan, Jonathan Monteiro, Daniel J Shinnick, Tanayott Thaweethai, Amber N Nguyen, Megan L Fitzgerald, Alice A Perlowski, Lauren E Stiles, Moira L Paskett, Stuart D Katz, Andrea S Foulkes, RECOVER Initiative Autopsy Group

Publikováno v: PLoS ONE, Vol 19, Iss 1, p e0285645 (2024)

ImportanceSARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or organ dysfunction after the acute phase of infection, termed Post-Acute Sequelae of SARS-CoV-2 (PASC), or long COVID. The characteristics, prevalence, trajectory and

Externí odkaz: https://doaj.org/article/47891beaef794c709c8dca7bd68c9151

Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.

Autor: Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A McComsey, Dylan McDonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M VanWagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Publikováno v: PLoS ONE, Vol 18, Iss 6, p e0286297 (2023)

ImportanceSARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, tr

Externí odkaz: https://doaj.org/article/c631b9a817d842aa8407fbc8f59463ab

Researching COVID to enhance recovery (RECOVER) pregnancy study: Rationale, objectives and design

Autor: Torri D. Metz, Rebecca G. Clifton, Richard Gallagher, Rachel S. Gross, Leora I. Horwitz, Vanessa L. Jacoby, Susanne P. Martin-Herz, Myriam Peralta-Carcelen, Harrison T. Reeder, Carmen J. Beamon, Marie-Abele Bind, James Chan, A. Ann Chang, Lori B. Chibnik, Maged M. Costantine, Megan L. Fitzgerald, Andrea S. Foulkes, Kelly S. Gibson, Nick Güthe, Mounira Habli, David N. Hackney, Matthew K. Hoffman, M. Camille Hoffman, Brenna L. Hughes, Stuart D. Katz, Victoria Laleau, Gail Mallett, Hector Mendez- Figueroa, Vanessa Monzon, Anna Palatnik, Kristy T.S. Palomares, Samuel Parry, Christian M. Pettker, Beth A. Plunkett, Athena Poppas, Uma M. Reddy, Dwight J. Rouse, George R. Saade, Grecio J. Sandoval, Shannon M. Schlater, Frank C. Sciurba, Hyagriv N. Simhan, Daniel W. Skupski, Amber Sowles, Tanayott Thaweethai, Gelise L. Thomas, John M. Thorp, Alan T. Tita, Steven J. Weiner, Samantha Weigand, Lynn M. Yee, Valerie J. Flaherman

ImportancePregnancy induces unique physiologic changes to the immune response and hormonal changes leading to plausible differences in the risk of developing post-acute sequelae of SARS-CoV-2 (PASC), or Long COVID. Exposure to SARS-CoV-2 during pregn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ebd7ef4e34c1faed1a599a056e969c2
https://doi.org/10.1101/2023.04.24.23289025

Enhanced maturation of human stem cell derived interneurons by mTOR activation

Autor: Stewart A. Anderson, Ethan M. Goldberg, Harrison Naung, Megan L. Fitzgerald, Neha Sehgal, Shane Fitzgerald, Jianhua Chu, William F. Manley

SummaryThe use of stem cell derived neurons for cell-based therapies is limited by a protracted maturation. We present a novel approach for accelerating the post-mitotic maturation of human stem cell derived interneurons via the activation of mTOR si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf24bf5fbb565918abaff6a39d12260

Ultrastructural localization of cannabinoid CB1 and mGluR5 receptors in the prefrontal cortex and amygdala

Autor: Megan L. Fitzgerald, Ken Mackie, Virginia M. Pickel

Publikováno v: J Comp Neurol

Stimulation of the postsynaptic metabotropic glutamate receptor mGluR5 triggers retrograde signaling of endocannabinoids that activate presynaptic cannabinoid CB1 receptors on juxtaposing axon terminals. To better understand the synaptic structure th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::307efb6ac82e53f11a9360c947e3f8b2
https://pubmed.ncbi.nlm.nih.gov/31008528