Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Megan L. Crichton"'
Autor:
Rebecca H. McLeese, Katherine O'Neill, Brenda O'Neill, James D. Chalmers, Jeanette Boyd, Anthony De Soyza, Ryan McChrystal, Megan L. Crichton, Judy M. Bradley
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background and objective There are limited data on airway clearance treatment (ACT) practices. This study aimed to: 1) assess the feasibility of collecting online surveys on ACTs from patients and physiotherapists and linking the patient survey data
Externí odkaz:
https://doaj.org/article/6620f91232e54d36bf5b2c67d2d94e2c
Autor:
Mike Lonergan, Alison J. Dicker, Megan L. Crichton, Holly R. Keir, Melissa K. Van Dyke, Hana Mullerova, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background Identifying patients with COPD at increased risk of poor outcomes is challenging due to disease heterogeneity. Potential biomarkers need to be readily available in real-life clinical practice. Blood eosinophil counts are widely st
Externí odkaz:
https://doaj.org/article/7f6b874d07b14579bce1f96c5d5f4a5c
Autor:
Amaia Artaraz, Megan L. Crichton, Simon Finch, Hani Abo-Leyah, Pieter Goeminne, Stefano Aliberti, Thomas Fardon, James D. Chalmers
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background Recurrent bronchiectasis exacerbations are related to deterioration of lung function, progression of the disease, impairment of quality of life, and to an increased mortality. Improved detection of exacerbations has been accomplis
Externí odkaz:
https://doaj.org/article/9cc83ac0fc9a427883a6b9a85063b66c
Autor:
Megan L. Crichton, Pieter C. Goeminne, Krizia Tuand, Thomas Vandendriessche, Thomy Tonia, Nicolas Roche, James D. Chalmers
Publikováno v:
European Respiratory Review, Vol 30, Iss 162 (2021)
Hospitalised patients with coronavirus disease 2019 (COVID-19) have a high mortality rate. There are an increasing number of published randomised controlled trials for anti-inflammatory, anti-viral and other treatments. The European Respiratory Socie
Externí odkaz:
https://doaj.org/article/09b3c24613744b6086132fc87940ad71
Autor:
James D. Chalmers, Megan L. Crichton, Gill Brady, Simon Finch, Mike Lonergan, Thomas C. Fardon
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Pulmonary rehabilitation improves exercise capacity and reduces risk of future exacerbation in COPD when performed after an exacerbation. There have been no previous studies of post-exacerbation rehabilitation in bronchiectasis. M
Externí odkaz:
https://doaj.org/article/0fd14e12b83d4f2293d60ffd01524088
Autor:
Holly R. Keir, Christopher J. Fong, Megan L. Crichton, Philip Barth, Eric Chevalier, Gill Brady, Gwen Kennedy, Johann Zimmermann, Piet L.B. Bruijnzeel, Alison J. Dicker, James D. Chalmers
Publikováno v:
ERJ Open Research, Vol 5, Iss 1 (2019)
Background Neutrophil elastase (NE) has been linked to lung neutrophil dysfunction in bronchiectasis and cystic fibrosis (CF), making NE inhibition a potential therapeutic target. NE inhibitor trials have given mixed result perhaps because not all pa
Externí odkaz:
https://doaj.org/article/dbb6e0c8f2a74736b2e41d63fdc9a609
Publikováno v:
European Respiratory Review, Vol 28, Iss 151 (2019)
Bronchiectasis is an increasing clinical problem, but multiple recent clinical trials have failed to reach their primary end-point. Difficulties in achieving “positive” bronchiectasis trials is reflected in a lack of agreement from trialists and
Externí odkaz:
https://doaj.org/article/0f18752150744cb89fad90d9a183d483
Autor:
James D Chalmers, Eva Polverino, Megan L Crichton, Felix C Ringshausen, Anthony De Soyza, Montserrat Vendrell, Pierre Régis Burgel, Charles S Haworth, Michael R Loebinger, Katerina Dimakou, Marlene Murris, Robert Wilson, Adam T Hill, Rosario Menendez, Antoni Torres, Tobias Welte, Francesco Blasi, Josje Altenburg, Michal Shteinberg, Wim Boersma, J Stuart Elborn, Pieter C Goeminne, Stefano Aliberti
Publikováno v:
EMBARC Registry Investigators 2023, ' Bronchiectasis in Europe : data on disease characteristics from the European Bronchiectasis registry (EMBARC) ', The Lancet Respiratory Medicine, vol. 11, no. 7, pp. 637-649 . https://doi.org/10.1016/S2213-2600(23)00093-0
Background: Bronchiectasis is a heterogeneous, neglected disease with few multicentre studies exploring the causes, severity, microbiology, and treatment of the disease across Europe. This aim of this study was to describe the clinical characteristic
Autor:
James D. Chalmers, Eva Polverino, Megan L. Crichton, Felix Ringshausen, Anthony De Soyza, Montserrat Vendrell, Pierre-Régis Burgel, Charles Haworth, Michael Loebinger, Katerina Dimakou, Marlene Murris, Robert Wilson, Adam Hill, Rosario Menéndez, Antoni Torres, Tobias Welte, Francesco Blasi, Josje Altenburg, Michal Shteinberg, W.G. Boersma, Stuart Elborn, Pieter Goeminne, Stefano Aliberti, EMBARC Registry Investigators
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b3ed94549a392d3fcf2a51b9c9fabe
https://doi.org/10.2139/ssrn.4325231
https://doi.org/10.2139/ssrn.4325231
Autor:
Raja, Dhar, Sheetu, Singh, Deepak, Talwar, B V, Murali Mohan, Surya Kant, Tripathi, Rajesh, Swarnakar, Sonali, Trivedi, Srinivas, Rajagopala, George, D'Souza, Arjun, Padmanabhan, B, Archana, P A, Mahesh, Babaji, Ghewade, Girija, Nair, Aditya, Jindal, Gayathri Devi H, Jayadevappa, Honney, Sawhney, Kripesh Ranjan, Sarmah, Kaushik, Saha, Suresh, Anantharaj, Arjun, Khanna, Samir, Gami, Arti, Shah, Arpan, Shah, Naveen, Dutt, Himanshu, Garg, Sunil, Vyas, Kummannoor, Venugopal, Rajendra, Prasad, Naveed M, Aleemuddin, Saurabh, Karmakar, Virendra, Singh, S K, Jindal, Shubham, Sharma, Deepak, Prajapat, Sagar, Chandrashekar, Michael, Loebinger, Aditi, Mishra, Francesco, Blasi, Ramanathan Palaniappan, Ramanathan, Pieter C, Goeminne, Preethi, Vasudev, Amelia, Shoemark, B S, Jayaraj, Rahul, Kungwani, Akanksha, Das, Mehneet, Sawhney, Eva, Polverino, Tobias, Welte, Nayan Sri, Gulecha, Michal, Shteinberg, Anshul, Mangala, Palak, Shah, Nishant Kumar, Chauhan, Nikita, Jajodia, Ashutosh, Singhal, Sakshi, Batra, Ashfaq, Hasan, Stefano, Aliberti, Megan L, Crichton, Sneha, Limaye, Sundeep, Salvi, James D, Chalmers
Publikováno v:
European Respiratory Journal. 61:2200611
BackgroundIdentifying risk factors for poor outcomes can help with risk stratification and targeting of treatment. Risk factors for mortality and exacerbations have been identified in bronchiectasis but have been almost exclusively studied in Europea