Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Megan L. Caraway"'
Autor:
Jennifer R. Honda, Sonia C. Flores, Megan L. Caraway, Diane J. Ordway, Edward D. Chan, Shaobin Shang, Randall J. Basaraba, Crystal A. Shanley, Ian M. Orme, Marcela Henao-Tamayo
Publikováno v:
The Open AIDS Journal
Background:Mycobacterium tuberculosisremains among the leading causes of death from an infectious agent in the world and exacerbates disease caused by the human immunodeficiency virus (HIV). HIV infected individuals are prone to lung infections by a
Autor:
Edward D. Chan, Marisa Harton, Gopinath S. Palanisamy, Marcela Henao Tamayo, Diane J. Ordway, Megan L. Caraway, Crystal A. Shanley, Ian M. Orme, Randall J. Basaraba, Shaobin Shang
Publikováno v:
Tuberculosis. 91:378-385
There is increasing evidence that clinical isolates of Mycobacterium tuberculosis that belong to the W-Beijing genotype of newly emerging strains are often of very high virulence when tested in small animal models, including the mouse and guinea pig.
Autor:
Crystal A. Shanley, Colleen Duncan, Andrés Obregón-Henao, Ian M. Orme, Shaobin Shang, Megan L. Caraway, Diane J. Ordway, Randall J. Basaraba
Publikováno v:
Mycobacterial Diseases.
Autor:
Marcela Henao-Tamayo, Diane J. Ordway, Ian M. Orme, David F. Ackart, Eileen A. Orme, Randall J. Basaraba, Shaobin Shang, Laurel Hascall-Dove, Crystal A. Shanley, Megan L. Caraway
Publikováno v:
Vaccine. 30(9)
Bacillus-Calmette-Guerin (BCG), the only human tuberculosis vaccine, primes a partially protective immune response against Mycobacterium tuberculosis infection in humans and animals. In guinea pigs, BCG vaccination slows the progression of disease an
Autor:
Marcela Henao-Tamayo, Ian M. Orme, Diane J. Ordway, Andrés Obregón-Henao, Crystal A. Shanley, Megan L. Caraway, Randall J. Basaraba, Laura Nold, Shaobin Shang, Colleen Duncan
Publikováno v:
Clinical and vaccine immunology : CVI. 18(9)
Despite issues relating to variable efficacy in the past, the Mycobacterium bovis BCG vaccine remains the basis for new-generation recombinant vaccines currently in clinical trials. To date, vaccines have been tested mostly against laboratory strains
Autor:
David F. Ackart, Diane J. Ordway, Anne J. Lenaerts, Marcela Henao-Tamayo, Ian M. Orme, Randall J. Basaraba, Megan L. Caraway, Eileen A. Orme, Laurel Hascall-Dove, Crystal A. Shanley, Shaobin Shang
The experimental compound TMC207 is showing promise against infections caused by Mycobacterium tuberculosis both in a variety of animal studies and in the field. In this study, we used the guinea pig model, a species that shows several similarities t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530f9cca3a721b35f527a0b12c343563
https://europepmc.org/articles/PMC3019667/
https://europepmc.org/articles/PMC3019667/
Autor:
David F. Ackart, Laurel Hascall-Dove, Crystal A. Shanley, Marcela Henao-Tamayo, Anne J. Lenaerts, Megan L. Caraway, Susan L. Kraft, Diane J. Ordway, Shaobin Shang, Ian M. Orme, Marisa Harton, Eileen A. Orme, Daniel S. Bucy, Randall J. Basaraba
Publikováno v:
Antimicrobial agents and chemotherapy. 54(5)
The purpose of this study was 2-fold. First, we evaluated standard chemotherapy in the guinea pig model of tuberculosis to determine if this animal species could productively be used for this purpose. Second, given the similarities of the pathology o
Autor:
Anne J. Lenaerts, Ian M. Orme, Gavin J. Ryan, Charles A. Peloquin, Randall J. Basaraba, Emily R. Driver, Megan L. Caraway, Elizabeth J. Brooks, Donald R. Hoff
Publikováno v:
Antimicrobial agents and chemotherapy. 52(11)
Metronidazole, which is used for the treatment of infections caused by anaerobic organisms, was evaluated in Mycobacterium tuberculosis -infected guinea pigs. M. tuberculosis can adapt to hypoxia, which is present in the primary lesions of infected g