Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Megan L Finch"'
Autor:
Katharine J Goodall, Megan L Finch-Edmondson, Joanne van Vuuren, George C Yeoh, Ian E Gentle, James E Vince, Paul G Ekert, David L Vaux, Bernard A Callus
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164003 (2016)
Apoptosis mediated by Bax or Bak is usually thought to be triggered by BH3-only members of the Bcl-2 protein family. BH3-only proteins can directly bind to and activate Bax or Bak, or indirectly activate them by binding to anti-apoptotic Bcl-2 family
Externí odkaz:
https://doaj.org/article/10cbdea384e44e65aaebf41fbee23257
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0114813 (2015)
The Yes-associated protein (YAP) is a potent transcriptional co-activator that functions as a nuclear effector of the Hippo signaling pathway. YAP is oncogenic and its activity is linked to its cellular abundance and nuclear localisation. Activation
Externí odkaz:
https://doaj.org/article/a18ed646f0b24c7bb5871055161104fd
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 54:288-303
Since their discovery more than a decade ago microRNAs have been demonstrated to have profound effects on almost every aspect of biology. Numerous studies in recent years have shown that microRNAs have important roles in development and in the etiolo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0114813 (2015)
PLoS ONE, Vol 10, Iss 2, p e0114813 (2015)
The Yes-associated protein (YAP) is a potent transcriptional co-activator that functions as a nuclear effector of the Hippo signaling pathway. YAP is oncogenic and its activity is linked to its cellular abundance and nuclear localisation. Activation
Autor:
Adam M. Passman, Robyn P. Strauss, Sarah B. McSpadden, Megan L. Finch-Edmondson, Ken H. Woo, Luke A. Diepeveen, Roslyn London, Bernard A. Callus, George C. Yeoh
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 12, Pp 1635-1641 (2015)
The choline-deficient, ethionine-supplemented (CDE) dietary model induces chronic liver damage, and stimulates liver progenitor cell (LPC)-mediated repair. Long-term CDE administration leads to hepatocellular carcinoma in rodents and lineage-tracing
Externí odkaz:
https://doaj.org/article/590a223ebd954ff28931048224c8ef47