Výsledky vyhledávání - "Megan L Falsetta"

Akademický článek

α-Mangostin disrupts the development of Streptococcus mutans biofilms and facilitates its mechanical removal.

Autor: Phuong Thi Mai Nguyen, Megan L Falsetta, Geelsu Hwang, Mireya Gonzalez-Begne, Hyun Koo

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111312 (2014)

α-Mangostin (αMG) has been reported to be an effective antimicrobial agent against planktonic cells of Streptococcus mutans, a biofilm-forming and acid-producing cariogenic organism. However, its anti-biofilm activity remains to be determined. We e

Externí odkaz: https://doaj.org/article/ecfc625146fb4bffb99dffe06c088c6f

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Akademický článek

The exopolysaccharide matrix modulates the interaction between 3D architecture and virulence of a mixed-species oral biofilm.

Autor: Jin Xiao, Marlise I Klein, Megan L Falsetta, Bingwen Lu, Claire M Delahunty, John R Yates, Arne Heydorn, Hyun Koo

Publikováno v: PLoS Pathogens, Vol 8, Iss 4, p e1002623 (2012)

Virulent biofilms are responsible for a range of infections, including oral diseases. All biofilms harbor a microbial-derived extracellular-matrix. The exopolysaccharides (EPS) formed on tooth-pellicle and bacterial surfaces provide binding sites for

Externí odkaz: https://doaj.org/article/8700aee9ca064b438a6977e7beb5a281

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Akademický článek

Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outermembrane proteins.

Autor: Nancy J Phillips, Christopher T Steichen, Birgit Schilling, Deborah M B Post, Richard K Niles, Thomas B Bair, Megan L Falsetta, Michael A Apicella, Bradford W Gibson

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38303 (2012)

Neisseria gonorrhoeae, the causative agent of gonorrhea, can form biofilms in vitro and in vivo. In biofilms, the organism is more resistant to antibiotic treatment and can serve as a reservoir for chronic infection. We have used stable isotope label

Externí odkaz: https://doaj.org/article/9d77ecd841c54724a4b1467a7f76f86a

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Akademický článek

The Composition and Metabolic Phenotype of Neisseria gonorrhoeae Biofilms

Autor: Michael A Apicella, Christopher T Steichen, Alastair G McEwan, Christine eCho, Megan L Falsetta, Margaret eKetterer, Jianqiang eShao, Jason eHunt, Michael P Jennings

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)

N. gonorrhoeae has been shown to form biofilms during cervical infection. Thus, biofilm formation may play an important role in the infection of women. The ability of N. gonorrhoeae to form membrane blebs is crucial to biofilm formation. Blebs contai

Externí odkaz: https://doaj.org/article/372f3b7c8da041cf96ca3a75276d83b7

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Akademický článek

Phasevarions mediate random switching of gene expression in pathogenic Neisseria.

Autor: Yogitha N Srikhanta, Stefanie J Dowideit, Jennifer L Edwards, Megan L Falsetta, Hsing-Ju Wu, Odile B Harrison, Kate L Fox, Kate L Seib, Tina L Maguire, Andrew H-J Wang, Martin C Maiden, Sean M Grimmond, Michael A Apicella, Michael P Jennings

Publikováno v: PLoS Pathogens, Vol 5, Iss 4, p e1000400 (2009)

Many host-adapted bacterial pathogens contain DNA methyltransferases (mod genes) that are subject to phase-variable expression (high-frequency reversible ON/OFF switching of gene expression). In Haemophilus influenzae, the random switching of the mod

Externí odkaz: https://doaj.org/article/08072cebc5074ae19882428ccdcc5b0b

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